2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P991498
    CAL-203 98%
    CAL-203 is a human monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. CAL-203 can be used in respiratory tract infections research.
    CAL-203
  • HY-P991499
    EVO-46120 98%
    EVO-46120 is a human monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. EVO-46120 can be used in respiratory syncytial virus (RSV) and metapneumovirus infections research.
    EVO-46120
  • HY-P991500
    EVO-46135 98%
    EVO-46135 is a human monoclonal antibody (mAb) targeting F/Fusion glycoprotein F0. EVO-46135 can be used in Respiratory syncytial virus infections and Metapneumovirus infections research.
    EVO-46135
  • HY-P991541
    HGS101 98%
    HGS101 is a fully human CCR5 monoclonal antibody with high affinity to CCR5. HGS101 binds to the 2nd extracellular loop (ECL-2) and acts as a signal antagonist. HGS101 restores Maraviroc (HY-13004) inhibition of Maraviroc-resistant HIV-1 infection of PBMCs. HGS101 shows anti-HIV activity by inhibiting CCR5 signaling in simian immunodeficiency virus-uninfected RMs models.
    HGS101
  • HY-P991606
    TRX585 98%
    TRX585 is a humanised anti-immunoglobulin-like transcript 5 (ILT5) monoclonal antibody. TRX585 has a potent immunoregulatory activity. TRX585 significantly activates human T cells and upregulates NKG2D and Fas ligand, followed by enhancing antitumor activity with potent cytotoxicity. TRX585 can be used for viral infections and malignancies research.
    TRX585
  • HY-P991653
    HGS004 98%
    HGS004 is a humanized IgG4 monoclonal antibody inhibitor targeting CCR5. HGS004 has potent antivival activity against a diverse panel of CCR5-tropic HIV-1 and durg (such as Maraviroc (HY-13004))-resistant strains. HGS004 can be used for HIV-1 infections research.
    HGS004
  • HY-P991655
    AGS-009 98%
    AGS-009 is a humanized monoclonal neutralising antibody targeting IFN-α. AGS-009 significantly reduces activated lymphocytes, such as CD4+ and CD8+ T cells as well as B cells in SIV infection rhesus macaque models. AGS-009 can be used for autoimmune diseases like systemic lupus erythematosus (SLE) and HIV infections research.
    AGS-009
  • HY-P991659
    SCH708980 98%
    SCH708980 is a humanized monoclonal antibody inhibitor targeting IL-10. SCH708980 has anti-immunosuppressive activity. SCH708980 can be used for visceral leishmaniasis, sepsis-associated kidney injury (SAKI) and osteoporosis research.
    SCH708980
  • HY-P991767
    Anti-Powassan virus E protein Antibody (POWV-63) 98%
    Anti-Powassan virus E protein Antibody (POWV-63) reacts with the envelope (E) protein of Powassan virus (POWV). Anti-Powassan virus E protein Antibody (POWV-63) shows significant protection against POWV-SPO, TBFVs, and Langat virus (LGTV) in vivo. Recommend Isotype Controls: Mouse IgG2c kappa, Isotype Control (HY-P99981).
    Anti-Powassan virus E protein Antibody (POWV-63)
  • HY-P991768
    Anti-Eastern equine encephalitis virus E2 protein Antibody (EEEV-3) 98%
    Anti-Eastern equine encephalitis virus E2 protein Antibody (EEEV-3) reacts with the B domain of the E2 glycoprotein on the eastern equine encephalitis virus (EEEV). Anti-Eastern equine encephalitis virus E2 protein Antibody (EEEV-3) exhibits a modest inhibition of viral attachment to the plasma membrane of the cells. Recommend Isotype Controls: Mouse IgG2c kappa, Isotype Control (HY-P99981).
    Anti-Eastern equine encephalitis virus E2 protein Antibody (EEEV-3)
  • HY-P991772
    Anti-WNV E protein DIII-LR Antibody (E16) 98%
    Anti-WNV E protein DIII-LR Antibody (E16) reacts with the domain III lateral ridge (DIII-LR) of the envelope (E) protein of West Nile Virus (WNV). Anti-Mouse CD11b Antibody (5C6) protects mice from WNV infection. Recommend Isotype Controls: Mouse IgG2b kappa, Isotype Control (HY-P99982).
    Anti-WNV E protein DIII-LR Antibody (E16)
  • HY-P991774
    Anti-West Nile virus NS1 Antibody (10NS1) 98%
    Anti-West Nile virus NS1 Antibody (10NS1) reacts with non-structural protein 1 (NS1) of West Nile virus (WNV). Anti-West Nile virus NS1 Antibody (10NS1) offers significant protection against flaviviral infections in vivo. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978).
    Anti-West Nile virus NS1 Antibody (10NS1)
  • HY-P991872
    Anti-ASGR1 Antibody 98%
    Anti-ASGR1 Antibody is an antibody against human ASGR1. Recommend Isotype Controls:?Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-ASGR1 Antibody
  • HY-P992076
    Anti-Candida auris β-1, 3 glucans Antibody (2G8) 98%
    Anti-Candida auris β-1,3-glucans Antibody (2G8) is an antibody targeting Candida auris β-1,3-glucans, and also acts as an inhibitor of AChE and TGF-β receptor 2. Anti-Candida auris β-1,3-glucans Antibody (2G8) also targets fungal cell wall components, effectively inhibits fungal growth and interferes with capsule formation, thereby significantly reducing the fungal load in mouse tissues. Anti-Candida auris β-1,3-glucans Antibody (2G8) not only blocks TGF-β receptor binding to inhibit the Smad signaling pathway, reduces fibroblast activation and collagen deposition, but also induces epithelial differentiation of tumor cells and reduces pancreatic tumor metastasis. Anti-Candida auris β-1,3-glucans Antibody (2G8) specifically binds to the conserved N-linked glycoepitope on AChE to inhibit its activity without interfering with BChE, and can be used in studies of cryptococcosis and related tumor mechanisms.The isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-Candida auris β-1, 3 glucans Antibody (2G8)
  • HY-P992077
    Anti-E8L Antibody (NL_A151) 98%
    Anti-E8L Antibody (NL_A151) is a recombinant monoclonal antibody specific for the E8L protein of monkeypox virus.
    Anti-E8L Antibody (NL_A151)
  • HY-P992079
    Anti-Flu A (H3N2) HA/Hemagglutinin Antibody (CR8043) 98%
    Anti-Flu A (H3N2) HA/Hemagglutinin Antibody (CR8043) is an antibody targeting influenza virus hemagglutinin (HA) that specifically neutralizes group 2 influenza viruses. Anti-Flu A (H3N2) HA/Hemagglutinin Antibody (CR8043) is applicable to research related to influenza virus infection.
    Anti-Flu A (H3N2) HA/Hemagglutinin Antibody (CR8043)
  • HY-P992080
    Anti-Flu A (H7N9) HA/Hemagglutinin Antibody (m826) 98%
    Anti-Flu A (H7N9) HA/Hemagglutinin Antibody (m826) is a humanized monoclonal antibody targeting H7N9. Anti-Flu A (H7N9) HA/Hemagglutinin Antibody (m826) induces antibody-dependent cellular cytotoxicity (ADCC) against cells expressing H7N9 HA. Anti-Flu A (H7N9) HA/Hemagglutinin Antibody (m826) is applicable to studies related to H7N9 avian influenza virus infection.
    Anti-Flu A (H7N9) HA/Hemagglutinin Antibody (m826)
  • HY-P992081
    Anti-H3L Antibody (NAL_A185) 98%
    Anti-H3L Antibody (NAL_A185) is a neutralizing antibody targeting the H3L envelope protein of vaccinia virus (CV) belonging to the genus Orthopoxvirus. By binding to the H3L protein of intracellular mature virions, Anti-H3L Antibody (NAL_A185) blocks the binding of the virus to host cells, thereby neutralizing viral infectivity. Anti-H3L Antibody (NAL_A185) not only protects BALB/c mice from intranasal challenge with the lethal vaccinia virus WR strain, reducing weight loss and mortality, but also exhibits complement-dependent neutralizing activity against monkeypox virus. Among these properties, NAL_A185 is an immune target induced by the smallpox vaccine Dryvax; it elicits a robust recall antibody response and induces high-titer neutralizing antibodies in mice. Anti-H3L Antibody (NAL_A185) can be used for studies related to vaccinia virus infection, monkeypox and monkeypox disease.
    Anti-H3L Antibody (NAL_A185)
  • HY-P992083
    Anti-Influenza HA Antibody (CR9114) 98%
    Anti-Influenza HA Antibody (CR9114) is an antibody against influenza virus hemagglutinin. Anti-Influenza HA Antibody (CR9114) binds to the conserved hemagglutinin (HA) stalk region of influenza A and B viruses, and mediates cross-subtype neutralization. Anti-Influenza HA Antibody (CR9114) is applicable for influenza-related research.
    Anti-Influenza HA Antibody (CR9114)
  • HY-P992097
    Fanolesomab 98%
    Fanolesomab is an anti-human CD15-targeting monoclonal antibody. Fanolesomab binds to the CD15 epitope on white blood cells to enable imaging of white blood cell distribution, migration, and infection sites. Fanolesomab can be used for the research of infection.
    Fanolesomab
Cat. No. Product Name / Synonyms Application Reactivity