Roflumilast Impurity E
Based on 1 Customer Validation
Roflumilast Impurity E is the impurity of Roflumilast. Roflumilast(Daliresp) is a agent which acts as a selective and long-acting inhibitor of the enzyme PDE-4 with an IC50 value of 0.8 nM.
For research use only. We do not sell to patients.
- Purity: 98.37%
- CAS No.: 1391052-76-8
- Formula: C13H8Cl2F2N2O3
- Molecular Weight:349.12
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
-
Help & FAQs
-
Immunology/Inflammation Compound Library
HY-L007
-
Metabolism/Protease Compound Library
HY-L012
-
Anti-Alzheimer's Disease Compound Library
HY-L069
-
Neurodegenerative Disease-related Compound Library
HY-L086
-
Anti-Colorectal Cancer Compound Library
HY-L103
-
Protein-protein Interaction Inhibitor Library
HY-L109
-
Heterocyclic Compound Library
HY-L138
-
Metabolic Enzyme Compound Library
HY-L146
-
Highly Selective Inhibitors Library
HY-L158
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Chemical Information
-
CAS No. 1391052-76-8
-
Appearance Solid
-
Molecular Weight 349.12
-
Formula C13H8Cl2F2N2O3
-
Color White to off-white
-
SMILES
O=C(NC1=C(Cl)C=NC=C1Cl)C2=CC=C(OC(F)F)C(O)=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (143.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (243 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8643 mL | 14.3217 mL | 28.6434 mL | 71.6086 mL |
| 5 mM | 0.5729 mL | 2.8643 mL | 5.7287 mL | 14.3217 mL | |
| 10 mM | 0.2864 mL | 1.4322 mL | 2.8643 mL | 7.1609 mL | |
| 15 mM | 0.1910 mL | 0.9548 mL | 1.9096 mL | 4.7739 mL | |
| 20 mM | 0.1432 mL | 0.7161 mL | 1.4322 mL | 3.5804 mL | |
| 25 mM | 0.1146 mL | 0.5729 mL | 1.1457 mL | 2.8643 mL | |
| 30 mM | 0.0955 mL | 0.4774 mL | 0.9548 mL | 2.3870 mL | |
| 40 mM | 0.0716 mL | 0.3580 mL | 0.7161 mL | 1.7902 mL | |
| 50 mM | 0.0573 mL | 0.2864 mL | 0.5729 mL | 1.4322 mL | |
| 60 mM | 0.0477 mL | 0.2387 mL | 0.4774 mL | 1.1935 mL | |
| 80 mM | 0.0358 mL | 0.1790 mL | 0.3580 mL | 0.8951 mL | |
| 100 mM | 0.0286 mL | 0.1432 mL | 0.2864 mL | 0.7161 mL |
Roflumilast Impurity E Related Classifications
HY-100640 Related Classifications
Powered by Bioz