1. JAK/STAT Signaling
    Stem Cell/Wnt
  2. STAT

STAT5-IN-2 

Cat. No.: HY-102048
Handling Instructions

STAT5-IN-2 is a STAT5 inhibitor with EC50s of 9 μM and 5 μM in K562 and KU812 cells, respectively. Potent antileukemic effect.

For research use only. We do not sell to patients.

STAT5-IN-2 Chemical Structure

STAT5-IN-2 Chemical Structure

CAS No. : 2111834-61-6

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  • Biological Activity

  • Technical Information

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  • References

Description

STAT5-IN-2 is a STAT5 inhibitor with EC50s of 9 μM and 5 μM in K562 and KU812 cells, respectively. Potent antileukemic effect[1].

IC50 & Target

EC50: 9 μM (K562 cells), 5 μM (KU812 cells)[1]

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5157 mL 12.5783 mL 25.1566 mL
5 mM 0.5031 mL 2.5157 mL 5.0313 mL
10 mM 0.2516 mL 1.2578 mL 2.5157 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

397.51

Formula

C₂₆H₂₇N₃O

CAS No.

2111834-61-6

SMILES

CC(CCN1CCOC2=CC(C=CN3)=C3C=C2)(C)C4=C1C=CC(C5=CC=CN=C5)=C4

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
STAT5-IN-2
Cat. No.:
HY-102048
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STAT5-IN-2

Cat. No.: HY-102048