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N-Desmethyl clomipramine-d3 hydrochloride
0 ImagesSynonyms: Desmethylclomipramine-d3 hydrochloride;Norclomipramine-d3 hydrochlorideN-Desmethyl clomipramine-d3 hydrochloride (Desmethylclomipramine-d3 hydrochloride; Norclomipramine-d3 hydrochloride) is the deuterated-labeled N-Desmethyl clomipramine hydrochloride (HY-12388A). N-Desmethyl clomipramine hydrochloride is the orally active major active metabolite of the tricyclic antidepressant Clomipramine (HY-B0457A), possessing multiple activities including anti-inflammatory, antioxidant, antibacterial, and antiparasitic effects. N-Desmethyl clomipramine hydrochloride blocks autophagosome-lysosome fusion, leading to the accumulation of LC3-II, p62, ATG7, WIPI2, and ATG5-12, reactivates the p53/p21 pathway, induces apoptosis through C-PARP and C-CAS3, and inhibits the proliferation, migration, and invasion of renal cancer cells. N-Desmethyl clomipramine hydrochloride inhibits LdTOPIA, inducing R-loop accumulation in the nucleus of Leishmania, ultimately causing parasite death. N-Desmethyl clomipramine hydrochloride can be used for research on depression, metastatic renal cell carcinoma, and leishmaniasis. -
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Ethyl acetoacetate-d3
0 ImagesCat. No.: HY-Y1093S4CAS No.: 1565868-21-4Ethyl acetoacetate-d3 is the deuterium labeled Ethyl acetoacetate. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds. Ethyl acetoacetate is an inhibitor of bacterial biofilm. -
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- PNU-101603
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- Ecabet sodium
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Xanthohumol C
0 ImagesXanthohumol C is a prenylchalcone, that can be isolated from the hops of Humulus lupulus. -
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2-Hydroxy-1-methoxyanthraquinone
0 Images2-Hydroxy-1-methoxyanthraquinone could be isolated from the stem bark of Morinda lucida Benth. (Rubiaceae) and possesses antibacterial activity. -
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- Ethyl Orsellinate
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Pinocembrin (Standard)
0 ImagesSynonyms: (+)-Pinocoembrin (Standard); Dihydrochrysin (Standard); Galangin flavanone (Standard)Pinocembrin (Standard) is the analytical standard of Pinocembrin. This product is intended for research and analytical applications. Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties. -
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4-Hydroxybenzoic acid-13C
0 ImagesSynonyms: p-Hydroxybenzoic acid-13C; PHBA-13C4-Hydroxybenzoic acid-13C is the 13C labeled 4-Hydroxybenzoic acid. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL. -
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Antimicrobial agent-8
0 ImagesCat. No.: HY-151402CAS No.: 2978694-22-1Antimicrobial agent-8 (Compound 15) is a potent antimicrobial agent, and shows potent antimicrobial activity with an MIC range of 2-8 μg/mL against Gram-negative and Gram-positive bacteria. Antimicrobial agent-8 shows anti-inflammatory activity against lipopolysaccharide-induced inflammation. -
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Erythromycin-13C2
0 ImagesCat. No.: HY-B0220S3CAS No.: 202114-52-1Erythromycin-13C2 is a macrolide antibiotic that can be used to treat respiratory infections, skin infections, and chlamydia infections. -
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Monascorubrin
0 ImagesMonascorubrin is a compound that can be isolated from Monascus mycelia. Monascorubrin has activities such as anti-inflammatory, anti-tumor, antibacterial, and immunomodulatory. Monascorubrin also has certain embryotoxicity, with an ED50 of 4.3 μg for chicken embryos. Monascorubrin can be used for the research of tumors and inflammatory diseases. -
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16-O-Deacetyl fusidic acid lactone
0 Images16-O-Deacetyl fusidic acid lactone (16-Deacetylfusidic acid γ-lactone) (FA-9) is a Fusidic acid (HY-B1350) (FA) lactone derivative with antibacterial effects. 16-O-Deacetyl fusidic acid lactone is effective against Gram-positive bacteria, but has no inhibitory effect on Gram-negative bacteria. -
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Doxycycline-d3 (hyclate) (major)
0 ImagesCat. No.: HY-N0565S1Doxycycline-d3 hyclate (major) is the deuterium labeled Doxycycline hyclate (HY-N0565B). Doxycycline hyclate is an orally active highly lipophilic, tissue-permeable MMP inhibitor with broad-spectrum antibacterial activity. Doxycycline hyclate is also a semi-synthetic antibiotic with chelating properties, which blocks bacterial protein synthesis and inhibits extracellular matrix degradation through interactions with zinc and calcium atoms. Doxycycline hyclate also inhibits mitochondrial biogenesis, translation, and the expression of respiratory chain proteins. Doxycycline hyclate induces apoptosis, inhibits autophagy and EMT, downregulates stem cell markers, and activates the PI3K-AKT pathway, thereby effectively inhibiting the viability and proliferation of cancer cells such as breast cancer cells. Doxycycline hyclate also promotes the survival and self-renewal of embryonic stem cells and neural stem cells, and reduces the frequency of medium changes in culture. Doxycycline hyclate has been applied in studies related to breast cancer, prostate cancer, bladder cancer, and other cancers. -
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Chloroorienticin A (Standard)
0 ImagesSynonyms: A82846B (Standard); LY 264826 (Standard); PA 45052A (Standard)Chloroorienticin A (Standard) is the analytical standard of Chloroorienticin A (HY-100997). This product is intended for research and analytical applications. Chloroorienticin A (A82846B) is a glycopeptide antibiotic. Chloroorienticin A exhibits excellent activity against staphylococci and streptococci. -
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Pivmecillinam hydrochloride (Standard)
0 ImagesSynonyms: FL-1039 hydrochloride (Standard)Pivmecillinam (hydrochloride) (Standard) is the analytical standard of Pivmecillinam (hydrochloride). This product is intended for research and analytical applications. Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic. -
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EcMetAP1-IN-1
0 ImagesEcMetAP1-IN-1 (compound 4) is an inhibitor of Escherichia coli methionine aminopeptidase MetAP1. -
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A-54556A
0 ImagesA-54556A (ADEP 1) is an acyldepsipeptide (ADEP) antibiotic. A-54556A shows antibacterial activity against a broad range of Gram-positive bacteria. -
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Bromochloro-5,5-dimethylhydantoin
0 ImagesCat. No.: HY-W077245CAS No.: 16079-88-2Synonyms: BCDMHBromochloro-5,5-dimethylhydantoin (BCDMH) is a fungicide. Bromochloro-5,5-dimethylhydantoin disrupts bacterial cell membranes, alters membrane structure and permeability, and induces leakage of soluble proteins and ions. Bromochloro-5,5-dimethylhydantoin is applicable to studies related to bacterial infections. -
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Resazurin sodium (Standard)
0 ImagesSynonyms: Diazoresorcinol sodium (Standard)Resazurin (sodium) (Standard) is the analytical standard of Resazurin (sodium). This product is intended for research and analytical applications. Resazurin sodium (Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin. -
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