2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-158124
    LasR antagonist 1
    		Antagonist
    LasR antagonist 1 (Compound 7) is an antagonist for LasR with an IC50 of 0.4 μM, that modulates the quorum sensing (QS) in the opportunistic pathogen Pseudomonas aeruginosa.
    LasR antagonist 1
  • HY-N19083
    Tecomella undulata extract
    Tecomella undulata Extract, also known as Rohida extract, is a valuable botanical extract derived from the bark and leaves of the Tecomella undulata plant native to the Indian Thar Desert and is rich in bioactive compounds such as flavonoids, quinones, triterpenoids, and other phytochemicals that contribute to its diverse therapeutic properties. This extract is widely recognized for its hepatoprotective effects demonstrated through its ability to protect against liver damage induced by toxins such as paracetamol and carbon tetrachloride by normalizing elevated liver enzyme levels reducing oxidative stress and improving liver function. Additionally, it exhibits significant anti-inflammatory activity comparable to standard drugs like indomethacin and has been used to treat conditions like ascites and hepatosplenomegaly while also showing immunomodulatory effects by enhancing both humoral and cell-mediated immune responses and possessing antimicrobial properties that make it effective against various pathogens. Recent research suggests that Tecomella undulata may have potential in managing nonalcoholic steatohepatitis (NASH) by reducing body weight insulin resistance and improving liver function markers making it a versatile natural remedy with significant applications in hepatoprotection anti-inflammation and immune support.
    Tecomella undulata extract
  • HY-B0239S1
    DL-threo-Chloramphenicol-d5
    		99.2%
    DL-threo-Chloramphenicol-d5 is a deuterium labeled DL-threo-Chloramphenicol. DL-threo-Chloramphenicol is the racemate of Chloramphenicol.
    DL-threo-Chloramphenicol-d<sub>5</sub>
  • HY-163292
    Antibacterial agent 180
    		Inhibitor
    Antibacterial agent 180 (15g), an appropriate substrate for the type I nitro reductases (TcNTR I), is a promising antitrypanosomatid agent. Antibacterial agent 180 (15g) shows nonmutagenic potential against Salmonella typhimurium strains (TA98, TA100, and TA102).
    Antibacterial agent 180
  • HY-N8336
    IT-143A
    		Inhibitor
    IT-143A is an antibiotic, that exhibits antibacterial and antifungal activity against Micrococcus luteus and Aspergillus fumigatus with MIC of 6.25-25 μg/mL. IT-143A inhibits growth of cancer cell KB with an IC50 of 0.36 ng/mL.
    IT-143A
  • HY-162527
    Antibacterial agent 216
    		Inhibitor
    Antibacterial agent 216 (Compound 2a) is an antibacterial agent that exhibits significant bactericidal effects when combined with INH and RIF. Antibacterial agent 216 has demonstrated remarkable in vitro anti-tuberculosis activity against Mtb H37Rv and MDR clinical isolates and can be used for tuberculosis research.
    Antibacterial agent 216
  • HY-N17440
    2-Methoxyjuglone
    		Inhibitor
    2-Methoxyjuglone, a naphthoquinone, is an apoptosis inducer. 2-Methoxyjuglone activates caspase-9 and caspase-3 via the mitochondrial cytochrome c-dependent intrinsic apoptosis cascade. 2-Methoxyjuglone increases pro-apoptotic Bax levels, decreases anti-apoptotic Bcl-2 levels, and promotes mitochondrial cytochrome c release. 2-Methoxyjuglone induces apoptosis morphological features, early apoptosis, S-phase and G2/M-phase cell cycle arrest, and DNA double-strand breaks. 2-Methoxyjuglone exerts activity against Gram-positive bacteria, pathogenic fungi, and phytopathogenic fungi. 2-Methoxyjuglone can be used for the research of hepatocellular carcinoma, osteosarcoma, colon adenocarcinoma, breast cancer, fungal infection, bacterial infection.
    2-Methoxyjuglone
  • HY-106998
    DC-756
    		Inhibitor
    DC-756 is a fluoroquinolone antibiotic. DC-756 possesses potent activity against Gram-positive and Gram-negative pathogens comparable to Trovafloxacin (HY-A0170), with MIC, against Ofloxacin (HY-B0125)-resistant strains 16-fold better than Trovafloxacin. DC-756 is well absorbed orally in rats and found to have good photostability. DC-756 can be used to study bacterial resistance.
    DC-756
  • HY-P5465
    Lactoferricin H, Lactotransferrin (37-61), human
    		Inhibitor
    Lactoferricin H, Lactotransferrin (37-61), human is a biological active peptide. (This is an antimicrobial peptide derived from human lactotransferrin amino acid residues 37-61.)
    Lactoferricin H, Lactotransferrin (37-61), human
  • HY-170609
    Antimicrobial agent-36
    		Inhibitor
    Antimicrobial agent-36 (Compound 8b) is an antimicrobial agent that significantly inhibits the level of DNA gyrase, with an IC50 value of 4.56 µM. Antimicrobial agent-36 can also be used for the preparation of nanopharmaceutical formulations, for the research and development of novel antibiotics.
    Antimicrobial agent-36
  • HY-101472
    Closthioamide
    		Inhibitor
    Closthioamide is a potent inhibitor of bacterial DNA gyrase and highly active against Ec, MRSA, VRE and Mv), with MICs of 9.00 μM, 0.58 μM, 0.58 μM and 72.03 μM respectively.
    Closthioamide
  • HY-P10402
    BMAP 28 (bovine)
    		Inhibitor
    BMAP 28, bovine is an antibacterial peptide. BMAP 28, bovine exhibits antimicrobial activity against gram-positive and gram-negative bacteria, by increasing cell membrane permeability, and causing leakage of cell contents. BMAP 28, bovine exhibits cytotoxicity to cancer cells and activated human lymphocytes. BMAP 28, bovine induces apoptosis through depolarization of mitochondrial membrane potential.
    BMAP 28 (bovine)
  • HY-B1802B
    Tosufloxacin hydrochloride
    		Inhibitor
    Tosufloxacin (A-61827) hydrochloride is an orally active fluoroquinolone antibiotic. Tosufloxacin hydrochloride shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria.
    Tosufloxacin hydrochloride
  • HY-143290
    Antibacterial agent 118
    		Inhibitor
    Antibacterial agent 118 (compound 20) is an antimycobacterial agent. Antibacterial agent 118 shows antibacterial activity against Mtb H37Ra, M. aurum, M. smegmatis, Mtb H37Rv and M. avium with MIC values of 40.7, 10.2, 163.0, 62.5 and 62.5 μM, respectively. Antibacterial agent 118 can be used for the research of tuberculosis.
    Antibacterial agent 118
  • HY-P3979
    Defensin HNP 4
    		Inhibitor
    Defensin HNP 4 (HNP 4) is a host-defense peptide that has antimicrobial activity against Gram-negative bacteria. Defensin HNP 4 inhibits ACTH stimulated synthesis of Corticosterone (HY-B1618) in rat adrenal cell suspensions.
    Defensin HNP 4
  • HY-N19311
    3,6-Bis(1-methylpropyl)-2(1H)-pyrazinone
    3,6-Bis(1-methylpropyl)-2(1H)-pyrazinone is an alkylated 2(1H)-pyrazinone derivative and cytotoxic agent found in the tunicate-derived actinomycete Streptomyces sp. Did-27.3,6-Bis(1-methylpropyl)-2(1H)-pyrazinone exhibits cytotoxic activity against cancer cells.3,6-Bis(1-methylpropyl)-2(1H)-pyrazinone can be used for the research of colorectal carcinoma, hepatocellular carcinoma, breast cancer.
    3,6-Bis(1-methylpropyl)-2(1H)-pyrazinone
  • HY-N9819
    Jinflexin D
    		Inhibitor
    Jinflexin D is a potential antibacterial agent, without inhibitory activity against methicillin-resistant Staphylococcus aureus (MRSA). Jinflexin D is a dimeric phenanthrene natural product with a unique seven-membered ring system, naturally extracted from the methanol extract of the roots of Juncus inflexus (a plant of the Juncaceae family).
    Jinflexin D
  • HY-112661
    PC-766B
    		Inhibitor
    PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na+, K+-ATPase.
    PC-766B
  • HY-P5664
    Maximin S4
    		Inhibitor
    Maximin S4 is an antimicrobial peptide derived from toad Bombina maxima. Maximin S4 has antibacterial activity against mycoplasma.
    Maximin S4
  • HY-13434AR
    Ionomycin calcium (Standard)
    		Inhibitor
    2-(1-Piperazinyl)pyrimidine (Standard) is the analytical standard of 2-(1-Piperazinyl)pyrimidine. This product is intended for research and analytical applications. 2-(1-Piperazinyl)pyrimidine is the major metabolite of Tandospirone (HY-14558).
    Ionomycin calcium (Standard)
Cat. No. Product Name / Synonyms Application Reactivity