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D-Arabinose-d2
0 ImagesCat. No.: HY-N0059S4CAS No.: 2419933-20-1D-Arabinose-d2 is the deuterated-labeled D-Arabinose (HY-N0059). D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-Arabinose (HY-N7082). -
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Thio-TEPA-d12
0 ImagesCat. No.: HY-W701673CAS No.: 1276372-62-3 -
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Undecanoic acid (Standard)
0 ImagesSynonyms: Undecanoate (Standard); Hendecanoic acid (Standard)Undecanoic acid (Standard) (Undecanoate (Standard)) is the analytical standard of Undecanoic acid (HY-W004282). This product is intended for research and analytical applications. Undecanoic acid is a monocarboxylic acid with antifungal property. Undecanoic acid inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum. -
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WK2
0 ImagesCat. No.: HY-P11616WK2 is an antibacterial agent. WK2 reduces serum TNF-α production induced by Bacterial infection. WK2 reduces wound size and promotes tissue repair in a skin wound infection model. WK2 exerts anti-inflammatory effects in a pneumonia model. WK2 can be used for research on infectious diseases such as pneumonia caused by bacterial infection. -
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Antituberculosis agent-6
0 ImagesCat. No.: HY-152136CAS No.: 2874263-72-4Antituberculosis agent-6 (compound 9g) is a potent antimycobacterial agent. Antituberculosis agent-6 shows significant activity against M. tuberculosis, with a MIC of 3.49 μM. Antituberculosis agent-6 also shows good antifungal activity against A. niger, with a MIC of 62.50 μM. Antituberculosis agent-6 shows high GI absorption. -
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Cephalexin-d5 monohydrate
0 ImagesCat. No.: HY-B0200BSSynonyms: Cefalexin hydrate-d5; Cephacillin hydrate-d5Cephalexin-d5 (monohydrate) is the deuterium labeled Cephalexin monohydrate. Cephalexin monohydrate is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin monohydrate kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al. -
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Zoledronic acid monohydrate (Standard)
0 ImagesCat. No.: HY-13777ARCAS No.: 165800-06-6Synonyms: Zoledronate monohydrate (Standard); CGP 42446 monohydrate (Standard); CGP42446A monohydrate (Standard); ZOL 446 monohydrate (Standard)Zoledronic acid (monohydrate) (Standard) is the analytical standard of Zoledronic acid (monohydrate). This product is intended for research and analytical applications. Zoledronic acid monohydrate (Zoledronate monohydrate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic acid monohydrate inhibits the differentiation and apoptosis of osteoclasts. Zoledronic acid monohydrate also has anti-cancer effects. -
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LasR-IN-1
0 ImagesCat. No.: HY-151160CAS No.: 3033530-75-2LasR-IN-1 (compound 9g) is a potent LasR inhibitor. LasR-IN-1 has good efficacy toward E. coli. LasR-IN-1 shows anti-bacterial activity, with a MIC of 28.13 μM against P. aeruginosa. -
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CHNQD-01748
0 ImagesCat. No.: HY-189347CAS No.: 3096111-98-4CHNQD-01748 is an Antibacterial agent. CHNQD-01748 disrupts mature biofilms and bacterial membranes, leading to bacterial lysis. CHNQD-01748 exhibits selective antibacterial activity against S. aureus and MRSA, with negligible activity against other Gram-positive bacteria, Gram-negative bacteria, and fungi. CHNQD-01748 can be used for research on MRSA infections. -
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Herbacetin-8-O-glucoside
0 ImagesCat. No.: HY-N20680CAS No.: 11021-22-0Herbacetin-8-O-glucoside (Compound 6) is a flavonoid glucoside, with no activity against Escherichia coli, Staphylococcus aureus Rosenbach, and Bacillus subtilis, and no cytotoxicity against cancer cells. -
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Antibacterial agent 244
0 ImagesCat. No.: HY-162923Antibacterial agent 244 is an orally active compound with broad-spectrum antibacterial activity, primarily targeting Gram-positive bacteria, with a MIC value of 1–4 μg/mL and low hemolytic toxicity (HC50 of 111.6 μg/mL). Antibacterial agent 244 disrupts bacterial transmembrane potential, increases membrane permeability, leading to leakage of cellular contents such as DNA and proteins, ultimately causing bacterial death. Antibacterial agent 244 can be used in research related to Gram-positive bacterial infections. -
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Abimufloxacin
0 ImagesCat. No.: HY-187837CAS No.: 1426216-93-4Synonyms: OPS-2071Abimufloxacin (OPS-2071) is a broad-spectrum quinolone antibacterial agent. Abimufloxacin inhibits the supercoiling activity of DNA gyrase, the decatenation activity of topoisomerase IV, the activation and proliferation of T cells, macrophage activity, as well as the production of TNF-α and IFN-γ. Abimufloxacin exhibits activity against enteropathogenic Gram-positive bacteria, Gram-negative bacteria, quinolone-resistant bacteria, and Crohn's disease-associated bacteria (including Clostridioides difficile and Campylobacter jejuni). Abimufloxacin alleviates colonic inflammation in a mouse model of T cell-mediated colitis. Abimufloxacin can be used in research related to diseases such as intestinal infections and Crohn's disease. -
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Ferrioxamine B
0 ImagesCat. No.: HY-185180CAS No.: 14836-73-8Ferrioxamine B is a bacterial desferrioxamine siderophore produced by actinomycetes. Ferrioxamine B acts as a ligand for FpvB and FoxA, and is transported into Pseudomonas aeruginosa via the FpvB and FoxA transporters. Ferrioxamine B competitively binds to FpvB, thereby antagonizing the uptake of thiostrepton into Pseudomonas aeruginosa. Ferrioxamine B can provide an iron source to support the growth of Pseudomonas aeruginosa under iron-limiting conditions. -
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Antibacterial agent 61
0 ImagesCat. No.: HY-139778CAS No.: 1426572-69-1Antibacterial agent 61 (example 27) is a antibacterial agent (extracted from patent WO2013030735A1). -
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Nemonoxacin-13C,d3
0 ImagesCat. No.: HY-14956S3Synonyms: TG-873870-13C,d3Nemonoxacin-13C,d3 (TG-873870-13C,d3) is the deuterium and 13C-labeled Nemonoxacin (HY-14956). Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae, and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia. -
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Carbendazim mixture with flusilazole
0 ImagesCat. No.: HY-135752CAS No.: 99827-19-7Carbendazim mixture with flusilazole is a fungicide used to control sooty mold caused by Botrytis narcissicola. The disease is the most common foliar disease of daffodils (Narcissus cultivars) in the UK and causes significant losses in bulb and flower production. Carbendazim mixture with flusilazole was found to be effective in reducing lesion size and significantly reducing symptoms of secondary sooty mold after spraying when used in combination with several other fungicides. In field trials in Cambridgeshire and Lincolnshire, a spraying program using this fungicide mixture was effective in controlling sooty mold. In addition, alternating four to six sprays using two or three fungicides with different modes of action not only reduced disease damage but also increased bulb production. The study discusses the selection of appropriate fungicides and control methods that may reduce the number of spraying applications. -
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Veratryl alcohol-13C
0 ImagesCat. No.: HY-W738271CAS No.: 91384-88-2Synonyms: 3,4-Dimethoxybenzyl alcohol-13CVeratryl alcohol-13C (3,4-Dimethoxybenzyl alcohol-13C) is the 13C-labeled Veratryl alcohol (HY-107858). Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy. -
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LeuRS-IN-1
0 ImagesCat. No.: HY-139987CAS No.: 1364914-72-6LeuRS-IN-1 is a potent, orally active M. tuberculosis leucyl-tRNA synthetase (M.tb LeuRS) inhibitor. LeuRS-IN-1 has IC50 and Kd values of 0.06 μM, 0.075 μM for M.tb LeuRS, respectively. LeuRS-IN-1 inhibits human cytoplasmic LeuRS (IC50=38.8 μM), and HepG2 protein synthesis (EC50=19.6 μM). -
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Cefotetan disodium
0 ImagesCat. No.: HY-108879CAS No.: 74356-00-6Cefotetan disodium is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis. -
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Angustifoline hydrochloride
0 ImagesCat. No.: HY-N10087ACAS No.: 133398-34-2Angustifoline hydrochloride, an alkaloid, can be isolated from Lupinus angustifolius L. alkaloid extract. Angustifoline hydrochloride exhibits antimicrobial activity. Angustifoline hydrochloride could have bacteriostatic effects against S. aureus, B. subtilis, E. coli, P. aeruginosa and B. thuringiensis. -
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