2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-163486
    Antituberculosis agent-10
    		Inhibitor
    Antituberculosis agent-10 (Compound 9) has excellent antibacterial activity against Mycobacterium tuberculosis (MIC = 0.3 μM). Antituberculosis agent-10 inhibits protein synthesis by targeting the 50S ribosomal subunit of the bacterium, thus exerting its antibacterial effect. Antituberculosis agent-10 is orally active.
    Antituberculosis agent-10
  • HY-13588A
    Cefsulodin
    		Inhibitor
    Cefsulodin (SCE-129) showed potent activity against Pseudomonas aeruginosa and strains susceptible to penicillin and gentamicin, with effectiveness comparable to that of gentamicin and debendazole. However, its effectiveness was diminished against penicillin-resistant strains of P. aeruginosa, particularly strains that were also resistant to gentamicin. For P. aeruginosa maltofila, SCE-129 showed similar minimum inhibitory concentrations to penicillin, gentamicin, and debendazole. Pseudomonas cepacia strains generally showed moderate resistance to SCE-129 and penicillin, and high resistance to gentamicin and debendazole.
    Cefsulodin
  • HY-174273
    Antibacterial agent 280
    		Inhibitor
    Antibacterial agent 280 (Compound 7af) is an antibacterial agent targeting methicillin-resistant and vancomycin-resistant Staphylococcus aureus (MRSA, VRSA). Antibacterial agent 280 is promising for research of is promising for research of S. aureus infections.
    Antibacterial agent 280
  • HY-B1828AR
    Spectinomycin dihydrochloride pentahydrate (Standard)
    		Inhibitor
    Spectinomycin (dihydrochloride pentahydrate) (Standard) is the analytical standard of Spectinomycin (dihydrochloride pentahydrate). This product is intended for research and analytical applications. Spectinomycin dihydrochloride pentahydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride pentahydrate acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride pentahydrate is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM-.
    Spectinomycin dihydrochloride pentahydrate (Standard)
  • HY-P11064
    G(IIKK)3I-NH2
    		Inhibitor
    G(IIKK)3I-NH2 is an antimicrobial peptide. G(IIKK)3I-NH2 exhibits potent antibacterial activity against both Gram-negative and Gram-positive bacteria. G(IIKK)3I-NH2 has low toxicity to primary cells and mice, and G(IIKK)3I-NH2 is not easy to induce bacterial resistance. G(IIKK)3I-NH2 can be used in the research of anti-infection agents.
    G(IIKK)3I-NH2
  • HY-153429
    FA-2
    		Inhibitor
    FA-2, a hydrogenated derivative of WU-FA-00, is an antibacterial agent that exhibits high levels of antibacterial activity against Gram-positive strains and also has some anti-inflammatory activity.
    FA-2
  • HY-133683R
    N-(3-Oxotetradecanoyl)-DL-homoserine lactone (Standard)
    N-(3-Oxotetradecanoyl)-DL-homoserine lactone (Standard) is the analytical standard of N-(3-Oxotetradecanoyl)-DL-homoserine lactone. This product is intended for research and analytical applications. N-(3-Oxotetradecanoyl)-DL-homoserine lactone, a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, is a quorum sensing (QS) signaling molecule[1][2].
    N-(3-Oxotetradecanoyl)-DL-homoserine lactone (Standard)
  • HY-137898
    Avilamycin A
    Avilamycin A is an oral active antibiotic. Avilamycin A is active against veterinary isolates of C. perfringens (MICs ≤ 0.06-0.5 mg/L) and B. hyodysenteriae (MICs = 12.5-100 μg/ml).
    Avilamycin A
  • HY-N3612
    Communic acid
    Communic acid ((+)-Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC50 of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging.
    Communic acid
  • HY-161860
    Antibacterial agent 233
    		Inhibitor
    Antibacterial agent 233 (Compound 7c) exhibits inhibitory efficacy against Helicobacter pylori with MIC of 0.4-1.6 μg/mL. Antibacterial agent 233 inhibits jack bean urease (IC50 is 0.27 μg/mL), changes the permeability of H. pylori cell membrane, causes the leakage of cellular contents. Antibacterial agent 233 exhibits metabolic stability in whole blood and artificial gastric fluid. Antibacterial agent 233 exhibits antitumor efficacy against U2OS in mice.
    Antibacterial agent 233
  • HY-184156
    WSL017
    		Inhibitor
    WSL017 is a cytochrome bd oxidase inhibitor with antibacterial activity against Mycobacterium tuberculosis. WSL017 can be used for the research of tuberculosis.
    WSL017
  • HY-147882
    Anti-MRSA agent 6
    		Inhibitor
    Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent. Anti-MRSA agent 6 shows low cytoxicity for MCF-7, A549 cells.
    Anti-MRSA agent 6
  • HY-P10556
    (KFF)3K
    		Inhibitor
    (KFF)3K is a cell penetrating peptide that can promote the absorption of other antibiotics by disrupting the outer membrane of bacteria. (KFF)3K can be introduced into a hydrocarbon scaffold to induce its antibacterial properties, making it an effective antimicrobial peptide. (KFF)3K can be used in the development of new antimicrobial agents.
    (KFF)3K
  • HY-N2564
    Isomagnolol
    		Inhibitor
    Isomagnolol is a lignan with antimicrobial activity. Isomagnolol can be isolated from the root of tea plant.
    Isomagnolol
  • HY-161922
    Antibacterial agent 235
    		Inhibitor
    Antibacterial agent 235 (compound thy2I) shows antibacterial activity with minimum inhibitory concentration (MIC) values ranging from 0.5 μg/mL to 8 μg/mL. Antibacterial agent 235 could kill both gram-positive and gram-negative bacteria via a membrane-targeting mechanism of action with a low frequency of resistance.
    Antibacterial agent 235
  • HY-108050
    4-Hydroxyoxyphenbutazone
    		Inhibitor
    4-Hydroxyoxyphenbutazone kills both replicating and nonreplicating (NR) Mycobacterium tuberculosis (Mtb), including Mtb resistant to standard agents. 4-Hydroxyoxyphenbutazone is a potent inhibitor of cytokine production. 4-Hydroxyoxyphenbutazone is an immunosuppressive agent and has the potential for rheumatoid arthritis research.
    4-Hydroxyoxyphenbutazone
  • HY-135873
    Germacrene B
    Germacrene B is a central intermediate in sesquiterpene biosynthesis. Germacrene B has been ascribed a warm, sweet, woody-spicy, geranium-like odour and is an important flavour constituent of lime peel oil. Germacrene B is also one of the main constituents of the essential oils from different plants that have antibacterial activity.
    Germacrene B
  • HY-N10585
    Malacidin B
    		Inhibitor
    Malacidin B is a macrocyclic lipopeptide antibiotic that shows antibacterial activity in a calcium-dependent manner.
    Malacidin B
  • HY-P5205
    Garvicin KS, GakA
    		Inhibitor
    Garvicin KS, GakA is a peptide at sizes of 34 amino acids to form bacteriocin garvicin KS (GarKS), with other 2 peptides, GakB, and GakC. Garvicin KS, GakA inhibits fibroblast viability and proliferation. Garvicin KS, GakA with GakB, is a potent combination with good peptide stability, antimicrobial efficacy, and fibroblast viability/proliferation effects. Garvicin KS peptides inhibit MSSA with MIC values in the order GakB >GakC >GakA.
    Garvicin KS, GakA
  • HY-139770
    Antibacterial agent 53
    		Inhibitor
    Antibacterial agent 53 (example 19) is a antibacterial agent (extracted from patent WO2013030735A1).
    Antibacterial agent 53
Cat. No. Product Name / Synonyms Application Reactivity