2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

Related Products

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1156A
    Cephradine sodium
    		Inhibitor
    Cephradine sodium is a broad-spectrum and orally active cephalosporin. Cephradine sodium is active against both gram-positive and gram-negative pathogens. Cephradine sodium is effective in eradicating most penicillinase-producing organisms. Cephradine sodium has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine sodium blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK.
    Cephradine sodium
  • HY-N12660
    Quorum sensing-IN-4
    		Inhibitor
    Quorum sensing-IN-4 (compound 2) is a quorum sensing inhibitor, and can be isolated from Thailand mangrove-derived Streptomyces strain, OUCMDZ-5511.
    Quorum sensing-IN-4
  • HY-14849
    PTZ601
    		Inhibitor
    PTZ601 (SMP 601) is an antibiotic, which inhibits the gram-positive bacteria, including the Vancomycin (HY-B0671)-resistant Enterococcus faecium (VREF) and Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). PTZ601 exhibits antimicrobial activity in infected mouse models.
    PTZ601
  • HY-168849
    Topoisomerase inhibitor 5
    		Inhibitor
    Topoisomerase inhibitor 5 (compound 158) is a Bacterial Topoisomerase Inhibitor inhibitor with the lowest inhibitory concentration of 0.125 μg/mL. Topoisomerase inhibitor has antituberculous activity.
    Topoisomerase inhibitor 5
  • HY-106338
    Polyketomycin
    		Inhibitor
    Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes. Polyketomycin inhibits growth of Gram-positive bacteria, and its MIC values is less than 0.2 µg/mL. Polyketomycin has antibacterial, anticancer, antimalarial activities.
    Polyketomycin
  • HY-N11719
    Clusin
    Clusin is a lignan that can be found in Hernandia nymphaeifolia. Clusin inhibits growth of the Gram-negative pathogen Neisseria gonorrhoeae. Clusin is inactive against murine lymphocytic leukemia cells and human cancer cells.
    Clusin
  • HY-115884
    PptT-IN-3
    PptT-IN-3 (compound 5p) is a potent inhibitor of with phosphopantetheinyl phosphoryl transferase (PptT) an IC50 of 3.5 μM. Phosphopantetheinyl transferase, an essential enzyme that plays a critical role in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. PptT-IN-3 has the potential for the research of tuberculosis.
    PptT-IN-3
  • HY-133002
    Methyl sterculate
    		Inhibitor
    Sterculic acid methyl ester is an ester form of sterculic acid, which is an inhibitor of Δ9 desaturase. Sterculic acid methyl ester (0.75 mM) inhibits the growth of, and is toxic to, the bacteria R. opacus. It decreases the fatty acid content, increases the ratio of palmitate to other fatty acids, and decreases the levels of stearate and oleate in R. opacus when used at concentrations of 0.25 or 0.5 mM. Sterculic acid methyl ester (50 ppm) has a synergistic effect on increased tumor growth induced by aflatoxin Q1 in rainbow trout.
    Methyl sterculate
  • HY-136440R
    Hydroxymetronidazole (Standard)
    		Inhibitor
    Hydroxymetronidazole (Standard) is the analytical standard of Hydroxymetronidazole. This product is intended for research and analytical applications. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle.
    Hydroxymetronidazole (Standard)
  • HY-182936
    Antibacterial agent 338
    		Inhibitor
    Antibacterial agent 338 (Compound 65) is an antibacterial agent and GyrB inhibitor, with an IC50 of 12.60 nM against GyrB from E. coli. Antibacterial agent 338 binds to the ATP-binding domain of E. coli GyrB, thereby inhibiting the ATPase activity of GyrB. Antibacterial agent 338 exhibits broad-spectrum antibacterial activity against multidrug-resistant Gram-negative bacteria. Antibacterial agent 338 reduces bacterial load in a neutropenic mouse thigh infection model. Antibacterial agent 338 can be used for the research of Acinetobacter baumannii infection.
    Antibacterial agent 338
  • HY-121268A
    Demeclocycline calcium
    		Inhibitor
    Demeclocycline calcium is an orally active tetracycline antibiotic that inhibits the binding of aminoacyl tRNA by binding to the 30S ribosomal subunit, thereby affecting protein synthesis. Demeclocycline calcium exhibits antibacterial activity against a broad spectrum of bacterial infections.
    Demeclocycline calcium
  • HY-106783AR
    Polymyxin B nonapeptide TFA (Standard)
    		Inhibitor
    Polymyxin B nonapeptide (TFA) (Standard) is the analytical standard of Polymyxin B nonapeptide (TFA). This product is intended for research and analytical applications. Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide TFA is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes[1][2][3].
    Polymyxin B nonapeptide TFA (Standard)
  • HY-161685
    Antibiofilm agent-8
    		Inhibitor
    Antibiofilm agent-8 (compound Ru2) enhances antimicrobial activity on visible-light exposure (400-700 nm, 10 J cm-2). Antibiofilm agent-8 generates of oxidative stress via NADH oxidation and ROS generation and compromises bacterial wall.
    Antibiofilm agent-8
  • HY-144735
    Anti-inflammatory agent 14
    		Inhibitor
    Anti-inflammatory agent 14 (compound 28) is an anti-inflammatory agent, with a MIC50 of 2 μM for Mtb H37Rv.
    Anti-inflammatory agent 14
  • HY-130338
    Teicoplanin A2-3
    		Inhibitor
    Teicoplanin A2-3 is an antibiotic active against Gram-positive aerobic and anaerobic bacteria.
    Teicoplanin A2-3
  • HY-B0272S3
    Rifampicin-d11
    		Inhibitor
    Rifampicin-d11 (Rifampin-d11; Rifamycin AMP-d11) is the deuterium labeled Rifampicin (HY-B0272). Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. Rifampicin shows anti-orthopoxvirus activity.
    Rifampicin-d<sub>11</sub>
  • HY-N7788
    cis-2-Dodecenoic acid
    		Inhibitor
    cis-2-Dodecenoic acid, originally discovered in Burkholderia cenocepacia, can interfere with the bacterial quorum sensing system and inhibit bacterial biofilm formation and virulence factor production.
    cis-2-Dodecenoic acid
  • HY-B1916R
    Acetylspiramycin (Standard)
    		Inhibitor
    Acetylspiramycin (Standard) is the analytical standard of Acetylspiramycin. This product is intended for research and analytical applications. Acetylspiramycin (Spiramycin B) is an effective oral macrolide antibiotic produced by Streptomyces, It can inhibit the splenic lymphocyte transformation induced by phytohemagglutinin (PHA), LPS (HY-D1056) and antigen, reduce the procoagulant activity of macrophages, have good antibacterial effect on gram-positive bacteria, and is also an effective antigenic insect agent, which can be used to fight parasitic infection[1][2][3][4].
    Acetylspiramycin (Standard)
  • HY-149875
    T3SS-IN-1
    T3SS-IN-1 (compound B9) is a potent inhibitor of type III secretion system (T3SS) inhibitor. T3SS-IN-1 can also inhibits hpa1 promoter activity and harpin protein expression without affecting bacterial growth.
    T3SS-IN-1
  • HY-149881
    Quorum sensing-IN-2
    		Inhibitor
    Quorum sensing-IN-2 (compound 23e) is a quorum sensing inhibitor, which can reduce the pathogenicity of bacteria without affecting bacterial growth. Quorum sensing-IN-2 inhibits bacterial infections with little hemolytic activity. Quorum sensing-IN-2 shows synergistic effect with Ciprofloxacin (HY-B0356) in the bacteremia model infected with P. aeruginosa PAO1.
    Quorum sensing-IN-2
Cat. No. Product Name / Synonyms Application Reactivity