-
Cathepsin Related Products (183)
Related Products (183)
-
Z-Val-Val-Arg-AMC
0 ImagesZ-Val-Val-Arg-AMC is a fluorescent peptide substrate that can be used to test the activity of cathepsins.
-
Cathepsin C-IN-5
0 ImagesCat. No.: HY-146584CAS No.: 2825567-97-1Cathepsin C-IN-5 (compound SF38) is a potent, selective and orally active Cathepsin C inhibitor with IC50s of 59.9 nM, 4.26 µM, >5 µM, >5 µM, >5 µM for Cat C, Cat L, Cat S, Cat B, Cat K, respectively. Cathepsin C-IN-5 inhibits the Cat C activity in bone marrow and blood. Cathepsin C-IN-5 decreases the activation of NSPs (neutrophil serine proteases). Cathepsin C-IN-5 shows anti-inflammatory activity.
-
Olgotrelvir sodium
0 ImagesCat. No.: HY-156655ACAS No.: 2763596-72-9Synonyms: STI-1558 sodiumOlgotrelvir (STI-1558) sodium is an orally active dual inhibitor of coronavirus main protease (Mpro) and human cell cathepsin (Cathepsin L). Olgotrelvir sodium is readily converted to its active form, AC1115, in full blood and/or plasma. Olgotrelvir sodium can effectively inhibit both SARS-CoV-2 replication and entry into host cells.
-
Z-Nle-Lys-Arg-AMC acetate
0 ImagesCat. No.: HY-155667APurity: 99.69%Z-Nle-Lys-Arg-AMC acetate is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range.
-
L-Arginine-7-amido-4-methylcoumarin hydrochloride
0 ImagesSynonyms: Arginine 4-methyl-7-coumarylamide hydrochlorideL-Arginine-7-amido-4-methylcoumarin (Arginine 4-methyl-7-coumarylamide) hydrochloride is a specific substrate of cathepsin H but not for cathepsins L and B.
-
L-Homocysteine (Standard)
0 ImagesL-Homocysteine (Standard) is the analytical standard of L-Homocysteine. This product is intended for research and analytical applications. L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia[1][2].
-
Cathepsin D and E FRET Substrate acetate
0 ImagesCat. No.: HY-P2498APurity: 99.75%Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D.
-
Z-Phe-Ala-diazomethylketone
0 ImagesSynonyms: PADKZ-Phe-Ala-diazomethylketone binds directly to Aβ42 monomers and small oligomers. Z-Phe-Ala-diazomethylketone inhibits the formation of Aβ42 dodecamers and inhibits Aβ42 fibril formation in the solution. Z-Phe-Ala-diazomethylketone has the potential for neurodegenerative disorders research.
-
N-CBZ-Phe-Arg-AMC hydrochloride
0 ImagesSynonyms: Z-FR-AMC hydrochloride
-
N-CBZ-Phe-Arg-AMC
0 ImagesSynonyms: Z-FR-AMCN-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes.
-
CatD-IN-1
0 ImagesCatD-IN-1 (Compound 5) is a Cathepsin D inhibitor with an IC50 of 0.44 μM. CatD-IN-1 holds potential for research in the field of osteoarthritis .
-
GB111-NH2 hydrochloride
0 ImagesCat. No.: HY-115454APurity: 98.41%
-
PTPσ Inhibitor, ISP
0 ImagesCat. No.: HY-P5982PTPσ Inhibitor, ISP is a PTPσ intracellular wedge domain mimetic peptide containing a TAT cell-penetrating domain, which acts as a PTPσ inhibitor. PTPσ Inhibitor, ISP binds to and inhibits PTPσ, thereby relieving CSPG-mediated axonal growth inhibition. PTPσ Inhibitor, ISP enhances CSPG degradation by promoting the secretion of Cathepsin B or MMP-2, and promotes DRG axonal growth, OPC migration and remyelination. PTPσ Inhibitor, ISP promotes nerve regeneration and improves sensory, motor and urinary functions in animal models of spinal cord injury, dorsal root injury and multiple sclerosis. PTPσ Inhibitor, ISP also increases the phosphorylation of ERK and AKT in colorectal cancer cells. PTPσ Inhibitor, ISP can be used in studies related to PTPσ/CSPG signaling, nerve regeneration, demyelinating diseases and RAS/ERK signaling.
-
Bz-FVR-AMC
0 ImagesBz-FVR-AMC is a fluorogenic substrate for procathepsin with a kcat/Km value of 1070 mM-1s-1. The high concentration of BZ-FVR-AMC inhibits the substrate.
