1. Autophagy
    Metabolic Enzyme/Protease
  2. Autophagy
    Cathepsin
  3. Asperphenamate

Asperphenamate 

Cat. No.: HY-129578
Handling Instructions

Asperphenamate, a fungal metabolite of Aspergillus flatiipes with anti-cancer effect, exhibits IC50 values of 92.3 μM, 96.5 μM and 97.9 μM in T47D, MDA-MB-231 and HL-60 cells, respectively.

For research use only. We do not sell to patients.

Asperphenamate Chemical Structure

Asperphenamate Chemical Structure

CAS No. : 63631-36-7

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Description

Asperphenamate, a fungal metabolite of Aspergillus flatiipes with anti-cancer effect, exhibits IC50 values of 92.3 μM, 96.5 μM and 97.9 μM in T47D, MDA-MB-231 and HL-60 cells, respectively[1][2].

In Vitro

Asperphenamate can inhibit cancer cell proliferation by fully inducing autophagy. asperphenamate showed inhibition effects against cathepsin L. At the same time, it also displayed weak inhibitory ability against cathepsin S.

Molecular Weight

506.59

Formula

C₃₂H₃₀N₂O₄

CAS No.

63631-36-7

SMILES

O=C(OC[[email protected]@H](NC(C1=CC=CC=C1)=O)CC2=CC=CC=C2)[[email protected]](CC3=CC=CC=C3)NC(C4=CC=CC=C4)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

AsperphenamateAutophagyCathepsinbreastcancerInhibitorinhibitorinhibit

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