2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. EAAT
  5. EAAT2 Isoform
  6. EAAT2 Activator

EAAT2 Activator

EAAT2 Activators (3):

Cat. No. Product Name Effect Purity
  • HY-12741
    LDN-212320
    		Activator 98.92%
    LDN-212320 (LDN-0212320) is a glutamate transporter (GLT-1)/excitatory amino acid transporter 2 (EAAT2) activator (at translational level). LDN-212320 (LDN-0212320) prevents nociceptive pain by upregulating astroglial GLT-1 expression in the hippocampus and ACC[1]
  • HY-183588
    HCM-01
    		Activator
    HCM-01 is an Excitatory amino acid transporter 2 (EAAT2) activator with oral effectiveness and blood-brain barrier penetration.HCM-01 binds to the allosteric site of EAAT2, increases EAAT2 expression in astrocytes, enhances glutamate-handling capacity, and modulates glutamate homeostasis.HCM-01 acts as an antioxidant, improves oxidative/antioxidative balance and increases total antioxidant capacity. HCM-01 can be used for the research of Alzheimer's disease.
  • HY-139692
    EAAT2 activator 1
    		Activator 98.91%
    EAAT2 activator 1 is the potent activator of excitatory amino acid transporter 2 (EAAT2). EAAT2 is the major glutamate transporter and functions to remove glutamate from synapses. EAAT2 activator 1 increases EAAT2 protein levels dose-dependently.