- Signaling Pathways
- Metabolic Enzyme/Protease
- Glycosidase
Glycosidase
Glycosidase
- [1]. Wang X, et al. Metabolites extracted from microorganisms as potential inhibitors of glycosidases (α-glucosidase and α-amylase): A review. Front Microbiol. 2022 Nov 17;13:1050869.
- [2]. Ohtsubo K, et al. Glycosylation in cellular mechanisms of health and disease. Cell. 2006 Sep 8;126(5):855-67. [Content Brief]
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Glycosidase Inhibitors
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Glycosidase Substrates
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Glycosidase Ligands
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Glycosidase Related Products (697)
Related Products (697)
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Antibodies (3)
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α-Amylase/α-Glucosidase-IN-21
0 ImagesCat. No.: HY-175605α-Amylase/α-Glucosidase-IN-21 (Compound 4) is a dual-functional inhibitor of α-Glucosidase and α-Amylase with IC50s of 0.27 and 0.19 µg/mL for α-Glucosidase and α-Amylase, respectively. α-Amylase/α-Glucosidase-IN-21 has an antidiabetic activity.α-Amylase/α-Glucosidase-IN-21 can be used for diabetes mellitus research. -
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Glucoamylase, Rhizopus sp.
0 ImagesGlucoamylase, Rhizopus sp. (Amyloglucosidase, Rhizopus sp.) is a starch-hydrolyzing enzyme with high catalytic efficiency towards soluble starch and raw starch. Glucoamylase, Rhizopus sp. hydrolyzes α-1,4 and α-1,6 glycosidic linkages in starch and similar substrates, and primarily releases β-glucose molecules from the non-reducing ends. Glucoamylase, Rhizopus sp. participates in glycogen metabolism and is associated with type II glycogen storage disease. Glucoamylase, Rhizopus sp. converts starch into glucose, and is applicable to the industrial production of high-fructose syrup, ethanol and other fermented products. -
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- Mortatarin F
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Shimobashiraside D
0 ImagesCat. No.: HY-N20687CAS No.: 1235289-00-5Shimobashiraside D is a dihydrochalcone C-glycoside found in the aerial parts of Keiskea japonica and is inactive against hyaluronidase. -
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- β1-3,6 Galactosidase, Xanthomonas manihotis
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α-Glucosidase-IN-77
0 ImagesCat. No.: HY-169411α-Glucosidase-IN-77 (Compound H7) is a non-competitive inhibitor for α-glucosidase with an IC50 of 1.25 μM. α-Glucosidase-IN-77 lowers blood glucose levels, improves glucose tolerance, regulates intestinal microbiota, and exhibits hepatoprotective effect in mouse type 2 diabetes model. -
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β,β-Trehalose
0 ImagesCat. No.: HY-W721582CAS No.: 499-23-0β,β-Trehalose is a analog of trehalose. β,β-Trehalose can support the growth of shoot tips of Cuscuta. β,β-Trehalose can be cleaved by nonspecific β-glucosidase. -
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α-Glucosidase-IN-93
0 ImagesCat. No.: HY-174839α-Glucosidase-IN-93 (Compound 5b) is a potent α-glucosidase inhibitor with an IC50 value of 49.18 nM. α-Glucosidase-IN-93 is promising for research of type 2 diabetes. -
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α-Galactosidase, Thermus brockianus
0 ImagesCat. No.: HY-P2871Hα-Galactosidase, Thermus brockianus (EC 3.2.1.22) is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. Two recombinant forms of α-Galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN). -
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CHI3L1-IN-7
0 ImagesCat. No.: HY-181783CAS No.: 2248987-74-6CHI3L1-IN-7 is a selective CHI3L1 inhibitor with a Kd of 7.40 μM and an IC50 of 15.4 μM. CHI3L1-IN-7 blocks CHI3L1's interaction with galectin-3, inhibits STAT3 phosphorylation, reduces the viability of multicellular 3D glioblastoma spheroids. CHI3L1-IN-7 can be used for the research of glioblastoma and CHI3L1-mediated tumor immune regulation. -
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PNGase F (MS grade)
0 ImagesCat. No.: HY-P2929DCAS No.: 83534-39-8PNGase F (MS grade), a glycosidase, catalyzes the cleavage of an internal glycoside bond in an oligosaccharide. PNGase F (MS grade) removes nearly all N-linked oligosaccharides from glycoproteins. PNGase F (MS grade) can be used for MS analysis. -
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- α-Glucosidase-IN-65
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O-GlcNAcase, Clostridium perfringens
0 ImagesCat. No.: HY-E71360O-GlcNAcase, Clostridium perfringens is a glycosidase derived from Clostridium perfringens, which functions in bacterial nutrient metabolism, host interaction and virulence regulation. O-GlcNAcase is a core enzyme in the cellular signal regulatory network and serves as a key target for various major and chronic diseases. O-GlcNAcase, Clostridium perfringens can be used for basic research and drug development of O-GlcNAcase due to its high conservation in catalytic mechanism and structure with human-derived enzymes. -
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α-Glucosidase-IN-8
0 ImagesCat. No.: HY-147879CAS No.: 2448345-96-6α-Glucosidase-IN-8 (Compound 4k) is a competitive α-glucosidase inhibitor with an IC50 of 0.18 µg/mL. -
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α-Glucuronidase, Cellvibrio japonicus
0 ImagesCat. No.: HY-E70101Bα-Glucuronidase, Cellvibrio japonicus (EC 3.2.1.139), is a glycosidase that hydrolyzes O- and S-glycosides. Its two substrates are α-D-glucuronide and water, and its two products are an alcohol and D-glucuronic acid. -
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- MPO-IN-7
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ALR2/α-Glucosidase-IN-2
0 ImagesCat. No.: HY-184330ALR2/α-Glucosidase-IN-2 is an inhibitor of α-glucosidase and aldose reductase ALR2. ALR2/α-Glucosidase-IN-2 has a Ki value of 11.68 nM against yeast α-glucosidase and a Ki value of 72.64 nM against ovine ALR2. ALR2/α-Glucosidase-IN-2 inhibits intestinal carbohydrate digestion regulatory enzymes and key enzymes in the polyol pathway. ALR2/α-Glucosidase-IN-2 can be used in diabetes-related research. -
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DNJNAc
0 ImagesSynonyms: 2-Acetamido-1,2-dideoxynojirmycinDNJNAc is an inhibitor of β-N-acetylglucosaminidases with a KiM value of 7 μM. -
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α-Glucosidase-IN-36
0 ImagesCat. No.: HY-149579CAS No.: 3025234-94-7α-Glucosidase-IN-36 (compound 5g) is a potent α-glucosidase inhibitor, with an IC50 of 6.69 ± 0.18 μM, Ki and Kis of 1.65 μM and 4.54 μM, respectively. α-Glucosidase-IN-36 may inhibit α-glucosidase activity by binding with its active site as well as changing the secondary structure of α-glucosidase. α-Glucosidase-IN-36 can be used for type 2 diabetes mellitus (T2DM) research. -
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2,7"-Phloroglucinol-6,6'-bieckol
0 ImagesCat. No.: HY-N11728CAS No.: 1621988-60-02,7"-Phloroglucinol-6,6'-bieckol is an orally active dual α-amylase/α-glucosidase inhibitor with IC50 values of 6.94 μM and 23.35 μM respectively. 2,7"-Phloroglucinol-6, 6'-bieckol alleviates postprandial hyperglycemia in diabetic mice. 2,7"-Phloroglucinol-6,6'-bieckol can be used in diabetes research. -
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