Influenza Virus
Influenza virus belongs to the Orthomyxoviridae group, which are enveloped, segmented, single-stranded negative sense RNA viruses. The group includes three types of influenza viruses, A, B and C. Type B and C viruses only infect humans, but the type A viruses infect humans, horses, swine, other mammals, and a wide variety of domesticated and wild birds. Human influenza A and B viruses cause seasonal epidemics of disease almost every winter in the United States. The emergence of a new and very different influenza virus to infect people can cause an influenza pandemic. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.
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Influenza Virus Related Products (728)
Related Products (728)
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Recombinant Proteins (585)
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Antibodies (1)
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Cyanidin 3-sambubioside chloride (Standard)
0 ImagesCat. No.: HY-N2533RCAS No.: 33012-73-6Synonyms: Cyanidin-3-O-sambubioside chloride (Standard)Cyanidin 3-sambubioside (chloride) (Standard) is the analytical standard of Cyanidin 3-sambubioside (chloride). This product is intended for research and analytical applications. Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride), a major anthocyanin, a natural colorant, and is a potent NO inhibitor. Cyanidin 3-sambubioside chloride is a H274Y mutation inhibitor, and inhibits influenza neuraminidase activity with an IC50 of 72 μM. Cyanidin 3-sambubioside chloride inhibits angiotensin-converting enzyme (ACE) activity and has antioxidant, anti-angiogenic and antiviral properties.
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BCX-1898
0 ImagesCat. No.: HY-105395CAS No.: 345267-14-3BCX-1898, a cyclopentane derivative, is an orally active and selective influenza virus neuraminidase inhibitor. BCX-1898 has antiviral activity with EC50s of <0.01-21 μM on influenza A (H1N1, H3N2, and H5N1) and influenza B viruses replication in MDCK cells. BCX-1898 shows protection against the mouse influenza model.
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PAN endonuclease-IN-1
0 ImagesCat. No.: HY-163147CAS No.: 2378640-67-4PAN endonuclease-IN-1 (Compound 23) is a potent PAN endonuclease inhibitor, with Kd values of 277 μM, 384 μM and 328 μM for WT, I38T and E23K PAN endonucleases, respectively. The RNA-dependent RNA polymerase acidic N-terminal (PAN) endonuclease, a critical component of influenza viral replication machinery, is an antiviral target.
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Antiviral agent 80
0 ImagesCat. No.: HY-181885CAS No.: 3110745-57-5Antiviral agent 80 is a conjugate of Zanamivir (HY-13210) and Amantadine (HY-13317), acting as a dual inhibitor of influenza virus M2 ion channel/neuraminidase (NA). Antiviral agent 80 exhibits potent inhibitory activity against both wild-type and drug-resistant influenza neuraminidase mutants, with an IC50 value range of 1.50 nM to 120.4 nM. Antiviral agent 80 can be used in influenza-related research.
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Influenza virus-IN-2
0 ImagesCat. No.: HY-143493CAS No.: 2411584-06-8Influenza virus-IN-2 (compound 19) is a potent influenza virus inhibitor with an EC50 of 2.58 µM and CC50 of 150.85 µM. Influenza virus-IN-2 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 489.39 nM. Influenza virus-IN-2 shows shows anti-influenza A virus activities.
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CYP2C19-IN-1
0 ImagesCat. No.: HY-151254CAS No.: 3010895-53-8CYP2C19-IN-1 (compound 20d) is a potent CYP2C19 inhibitor, possessing no hepatotoxicity and ames toxicity. CYP2C19-IN-1 inhibits RNA-dependent RNA polymerase (RdRP) with a Ki value of 6.16 µM. CYP2C19-IN-1 can be used in study of anti-ZIKV.
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Colletodiol
0 ImagesCat. No.: HY-135766CAS No.: 21142-67-6Synonyms: (+)-ColletodiolColletodiol is a fungal metabolite that has been found in D. grovesii and has immunosuppressant and antiviral activities. It inhibits concanavalin A- or LPS-induced proliferation of isolated mouse splenocytes (IC50s=12 and 5 μg/mL, respectively).1 Colletodiol inhibits influenza A viral replication in HeLa-IAV-Luc cells.
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Favipiravir sodium
0 ImagesCat. No.: HY-14768ACAS No.: 1366418-99-6Synonyms: T-705 sodiumFavipiravir (T-705) sodium is an inhibitor of viral RNA polymerase (RNA polymerase), which is converted into its active form Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the activity of influenza virus RNA-dependent RNA polymerase (RdRP) with an IC50 of 341 nM.
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IAV-IN-5
0 ImagesCat. No.: HY-183313CAS No.: 3038861-11-6IAV-IN-5 is an orally active inhibitor of influenza A virus (IAV). IAV-IN-5 inhibits viral replication, blocks virus-induced apoptosis, oxidative stress and cytokine storm, and regulates host immune signaling pathways. IAV-IN-5 reduces viral load and inflammatory cytokine levels in lung tissues of IAV-infected mouse models, alleviates body weight loss and pulmonary pathological damage. IAV-IN-5 can be used in studies related to influenza A virus infection.
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Trifluoperazine-d3 dihydrochloride
0 ImagesCat. No.: HY-B0532ASCAS No.: 1432064-02-2Trifluoperazine-d3 (dihydrochloride) is deuterium labeled Trifluoperazine (dihydrochloride). Trifluoperazine dihydrochloride, an antipsychotic agent, acts by blocking central dopamine receptors. Trifluoperazine dihydrochloride is a potent α1-adrenergic receptor antagonist. Trifluoperazine dihydrochloride is a potent NUPR1 inhibitor exerting anticancer activity. Trifluoperazine dihydrochloride is a calmodulin inhibitor, and also inhibits P-glycoprotein. Trifluoperazine dihydrochloride can be used for the research of schizophrenia. Trifluoperazine dihydrochloride acts as a reversible inhibitor of influenza virus morphogenesis.
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Actiphenol
0 ImagesCat. No.: HY-W399940CAS No.: 526-02-3Actiphenol is an antibiotic against coxsackievirus B3 and influenza A virus (IC50s = 14.37 and 34.4 µg/mL, respectively). Actiphenol is also an aromatic ketone that exhibits weak eukaryotic translation inhibiton activity, which is found in Streptomyces species. Actiphenol can be used as a key intermediate to synthesize Cycloheximide (HY-12320).
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Ganoderic acid T-N
0 ImagesCat. No.: HY-129152CAS No.: 112430-64-5Ganoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and 42 μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4 μM).
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N-Acetylneuraminic acid-13C-1
0 ImagesCat. No.: HY-I0400S1CAS No.: 1032998-24-5Synonyms: NANA-13C-1; Lactaminic acid-13C-1N-Acetylneuraminic acid-13C-1 is the 13C labeled N-Acetylneuraminic acid.
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Nylidrin hydrochloride (Standard)
0 ImagesNylidrin (hydrochloride) (Standard) is the analytical standard of Nylidrin hydrochloride (HY-B1404). This product is intended for research and analytical applications. Nylidrin hydrochloride (Buphenine hydrochloride) is an orally active β-adrenergic agonist. Nylidrin hydrochloride antagonizes NR1A/2B NMDA receptors (IC50 = 0.18 μM in Xenopus oocytes). Nylidrin hydrochloride reduces the levels of NP, HA, and M1. Nylidrin hydrochloride has antiviral activity against multiple H1N1 subtype influenza A viruses. Nylidrin hydrochloride improves hemorrhagic shock and anti-allergic effects.
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Herquline A
0 ImagesCat. No.: HY-125705CAS No.: 71812-08-3Synonyms: Herqueline AHerquline A (Herqueline A) is a fungal piperazine alkaloid. Herquline A is a fungal metabolite that inhibits platelet aggregation and replication of the influenza virus.
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Influenza HA (529-537)
0 ImagesCat. No.: HY-P11145CAS No.: 216876-10-7Influenza HA (529-537) is the amino acid sequence (IYATVAGSL) at positions 529-537 of the hemagglutinin (HA) of the influenza A virus. Influenza HA (529-537) can be recognized by three different specificities (H1-specific, H2-specific, H1/H2 cross-reactive) of CD8+ cytotoxic T-lymphocyte (CTL) clones. Influenza HA (529-537) can be used to understand T-cell immune specificity and to design new vaccines.
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Tirfipiravir
0 ImagesCat. No.: HY-156656CAS No.: 2759996-93-3Tirfipiravir is a nucleoside compound and antiviral agent, against the novel coronavirus or influenza virus.
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Influenza A virus-IN-4
0 ImagesCat. No.: HY-146004CAS No.: 2390067-58-8Influenza A virus-IN-4 (compound 23b), an Oseltamivir derivative, is a potent inhibitor of neuraminidase. Influenza A virus-IN-4 exerts powerful inhibitions on influenza viruses.
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GLFGAIAGFIENGWEGMIDG
0 ImagesCat. No.: HY-P12139CAS No.: 117138-20-2GLFGAIAGFIENGWEGMIDG is an influenza hemagglutinin fusion peptide and membrane disruptor composed of 20 amino acids. GLFGAIAGFIENGWEGMIDG transiently adopts an activated double-helix conformation under low pH conditions; meanwhile, it self-assembles into oligomers with a stable trimeric core, which further form pentamers and hexamers capable of inducing membrane bending, thinning and long-range disruption. GLFGAIAGFIENGWEGMIDG promotes the protrusion of lipid tails and the penetration of polar heads in phospholipid membranes, and is widely used in influenza-related studies.
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Indomethacin sodium hydrate (Standard)
0 ImagesSynonyms: Indometacin sodium hydrate (Standard)Dimethenamide-P (Standard) is the analytical standard of Dimethenamide-P. This product is intended for research and analytical applications. Dimethenamide-P is an amide herbicide effective for the pre-emergence management of annual grasses, small-seeded broadleaf weeds, and sedges in ornamental plants, functioning by inhibiting the synthesis of long-chain fatty acids.
