RAR/RXR Modulator
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Oxybenzone
0 ImagesOxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells.
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BMS453
0 ImagesSynonyms: BMS-189453BMS453 (BMS-189453), a synthetic retinoid, is a RARβ agonist and a RARα/RARγ antagonist. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.
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RXR antagonist 1
0 ImagesRXR antagonist 1 (compound 6a) is a retinoid X receptor (RXR) modulator. RXR antagonist 1 shows potent RXR-antagonistic activity, with a pA2 of 8.06. RXR antagonist 1 can be used for type 2 diabetes research.
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Oxybenzone (Standard)
0 ImagesOxybenzone (Standard) is the analytical standard of Oxybenzone. This product is intended for research and analytical applications. Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells.
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LG101506
0 ImagesCat. No.: HY-108524CAS No.: 331248-11-4
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LG100754 (Standard)
0 ImagesCat. No.: HY-108523RCAS No.: 180713-37-5Synonyms: UVI 2112 (Standard)LG100754 (Standard) is the analytical standard of LG100754 (HY-108523). This product is intended for research and analytical applications. LG100754 (UVI 2112) is a RXR dimers modulater. LG100754 acts as a RXR:RXR homodimer antagonist, but functions as a agonist towards RXR:PPARα and RXR:PPARγ heterodimers. LG100754 is an insulin sensitizer that functions through RXR.
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BMS453 (Standard)
0 ImagesCat. No.: HY-100608RCAS No.: 166977-43-1Synonyms: BMS-189453 (Standard)BMS453 (Standard) is the analytical standard of BMS453 (HY-100608). This product is intended for research and analytical applications. BMS453 (BMS-189453), a synthetic retinoid, is a RARβ agonist and a RARα/RARγ antagonist. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.
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11-Hydroxysugiol
0 ImagesCat. No.: HY-107218CAS No.: 88664-08-811-Hydroxysugiol regulates the SUMOylation of intracellular receptors by modulating RARα and vitamin D3 receptor (VDR).
