RSV
Respiratory syncytial virus
RSV (Respiratory syncytial virus) is a leading cause of acute respiratory infections. RSV can exploit host immunity and cause a strong inflammatory response that leads to lung damage and virus dissemination. There is a single RSV serotype with two major antigenic subgroups, A and B.
RSV is a non-segmented negative-sense single-stranded enveloped RNA virus that belongs to the family of Paramyxoviridae, genus Pneumovirus, subfamily Pneumovirinae. Its 10 genes encode 11 proteins since two overlapping open reading frames in the M2 mRNA yield two distinct matrix proteins, M2-1 and M2-2. The viral envelope contains three proteins, the G glycoprotein, the fusion (F) glycoprotein, and the small hydrophobic (SH) protein. The RSV virus comprises five other structural proteins, the large (L) protein, nucleocapsid (N), phosphoprotein (P), matrix (M), and M2-1, and two non-structural proteins (NS1 and NS2).
All Product Categories
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RSV Related Products (144)
Related Products (144)
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Recombinant Proteins (11)
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Antibodies (1)
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Sisunatovir hydrochloride
0 ImagesSynonyms: RV521 hydrochloride
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GHP-88309
0 ImagesGHP-88309 is a broad-spectrum, orally active antiviral agent targeting paramyxoviruses, that targets the viral polymerase, interupts the viral RNA synthesis, and inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with EC50 of 0.06-1.2 μM. GHP-88309 exhibits anti-infectious efficacy in mouse models.
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Ribavirin (Standard)
0 ImagesSynonyms: Ribasphere (Standard)Ribavirin (Standard) is the analytical standard of Ribavirin. This product is intended for research and analytical applications. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV. Ribavirin also has anti-orthopoxvirus and anti-variola activities.
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Suptavumab
0 ImagesCat. No.: HY-P99586CAS No.: 1629615-23-1Synonyms: REGN2222
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JNJ 2408068
0 ImagesCat. No.: HY-11098CAS No.: 317846-22-3Synonyms: R170591
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MAY0132
0 ImagesMAY0132 is a potent and selective EPAC2 inhibitor with an IC50 of 0.4 μM. MAY0132 significantly inhibits replication of HMPV, AdV and RSV, reduces viral infection-induced cytokine/chemokine production, and inhibits NF-κB activation. MAY0132 has antiviral activity and can be used in the study of respiratory virus infection.
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Asvasiran sodium
0 ImagesCat. No.: HY-158824ACAS No.: 1386946-83-3Synonyms: ALN-RSV01 sodiumAsvasiran sodium is a siRNA that targets the respiratory syncytial virus (RSV) N gene and inhibits viral replication.
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RSM-01
0 ImagesCat. No.: HY-P991492RSM-01 is a monoclonal antibody targeting site Ø of the pre-fusion F glycoprotein (Fusion glycoprotein F0) of respiratory syncytial virus (RSV). RSM-01 can be used in studies related to RSV infection.
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GS-443902
0 ImagesCat. No.: HY-126303CAS No.: 1355149-45-9Synonyms: GS-441524 triphosphate; Remdesivir metabolite
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2-5A pentasodium solution (100 mM)
0 ImagesCat. No.: HY-173189ASynonyms: 2′,5′-ApApA pentasodium; 2′,5′-trioligoadenylate pentasodium; 5'-O-Triphosphoryladenylyl-(2'→5')-adenylyl-(2'→5')-adenosine pentasodium2-5A (2′,5′-ApApA) pentasodium solution 100 mM is a high-affinity (Ka=0.04 nM) RNase L binder. 2-5A pentasodium solution 100 mM activates the nuclease activity of latent RNase L to cleave single-stranded RNA by inducing conformational changes and dimerization of latent RNase L, thereby mediating critical antiviral responses and enhancing interferon effects. 2-5A pentasodium solution 100 mM not only effectively inhibits Rauscher murine leukemia virus replication, reduces viremia and splenomegaly, but also enhances antileukemic efficacy when combined with amphotericin B and exhibits favorable high-dose tolerance. 2-5A pentasodium solution 100 mM is an important tool molecule for investigating the pathological mechanisms of viral infection, hereditary prostate cancer and leukemia.
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(S)-Enzaplatovir
0 ImagesSynonyms: (S)-BTA-C585
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Enzaplatovir
0 ImagesSynonyms: BTA-C585
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RSV-IN-1
0 ImagesRSV-IN-1 is a human respiratory syncytical virus (hRSV) inhibitor, with an IC50 of 0.11 μM.
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3,4-Di-O-caffeoyl quinic acid methyl ester
0 ImagesSynonyms: Macroantoin F
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2-5A
0 ImagesCat. No.: HY-173189CAS No.: 65954-93-0Synonyms: 2′,5′-ApApA; 2′,5′-trioligoadenylate; 5'-O-Triphosphoryladenylyl-(2'→5')-adenylyl-(2'→5')-adenosine2-5A is a RNase L activator, signal mediator and innate immune second messenger. 2-5A induces the expression of interferons and interferon-stimulated genes in recipient cells in a RNase L-dependent manner. 2-5A inhibits tumor growth in mouse models via paracrine RNase L activation derived from cancer cells. 2-5A can be used in studies related to viral infection and cancer.
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Roflumilast-d4
0 ImagesCat. No.: HY-15455SCAS No.: 1398065-69-4Synonyms: APTA-2217-d4; BYK 20869-d4; B9302-107-d4Roflumilast-d4 is the deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells.
