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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3823):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W288375
    (R)-3-Hydroxytetradecanoic acid
    		≥98.0%
    (R)-3-Hydroxytetradecanoic acid is an ester product.
    (R)-3-Hydroxytetradecanoic acid
  • HY-171702
    8PPD-Q
    		99.88%
    8PPD-Q, a para-phenylenediamine quinonec, is a rubber antioxidant. 8PPD-Q has superior antioxidant and anti-ozone activities but is toxic to the aquatic species, especially salmonids. 8PPD-Q can be used for environmental pollution research.
    8PPD-Q
  • HY-114591
    Spiromesifen
    		99.42%
    Spiromesifen (BSN 2060) is a broad-spectrum tetrachloro acid derivative acaricide. Spiromesifen reduces lipid biosynthesis via inhibition of acetyl-CoA carboxylase, and has no cross-resistance to any resistant mite or whitefly populations.
    Spiromesifen
  • HY-W006833
    1-Phenylindole
    		99.78%
    1-Phenylindole (Compound 8) is a 1-Phenylbenzimidazole analogue. 1-Phenylindole shows IC50 values of >50 μM and >50 μM for PDGFR and FGFR, respectively. 1-Phenylbenzimidazole is a selective PDGFR inhibitor.
    1-Phenylindole
  • HY-N7065
    Dihydralazine sulfate
    		98.0%
    Dihydralazine sulfate is an antihypertensive hydrazine derivative and also a low-potency genotoxic agent. Dihydralazine sulfate is a direct-acting mutagen with a mixed gene mutation mechanism, which induces DNA fragmentation in the lung, kidney and spleen of mice, and induces sister chromatid exchange in mouse bone marrow cells. Dihydralazine sulfate specifically kills DNA repair-deficient bacteria. Dihydralazine sulfate is a vasodilator and antihypertensive agent that reduces systemic vascular resistance, increases cardiac output and heart rate, thereby lowering blood pressure. Dihydralazine sulfate can be used in research related to hypertension and severe early-onset preeclampsia.
    Dihydralazine sulfate
  • HY-W105739
    18-Hydroxyoctadecanoic acid
    		99.69%
    18-Hydroxyoctadecanoic acid (Octadecanoic acid, 18-hydroxy) is an ester product.
    18-Hydroxyoctadecanoic acid
  • HY-147240
    Acloproxalap
    		99.92%
    Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, organ diseases, and viral infection-related syndromes.
    Acloproxalap
  • HY-133860
    Chrysoobtusin
    		99.45%
    Chrysoobtusin is an anthraquinone derivative isolated from Semen Cassiae. Semen Cassiae has long been used to protect liver, brighten eyes, and relieve constipation.
    Chrysoobtusin
  • HY-P4047
    Cyclo(RGDfK(Mal))
    		99.30%
    Cyclo(RGDfK(Mal)) is a pentapeptide. Cyclo(RGDfK(Mal)) improves the attachment and infiltration of human pluripotent stem cells. Cyclo(RGDfK(Mal)) can be used for 3D stem cell culture and expansion.
    Cyclo(RGDfK(Mal))
  • HY-105270A
    Tallimustine hydrochloride
    		98.23%
    Tallimustine hydrochloride, a distamycin-A derivative, is an anticancer agent.
    Tallimustine hydrochloride
  • HY-B1149A
    Bacampicillin (hydrochloride)
    		99.94%
    Bacampicillin hydrochloride is an orally active semi-synthetic aminopenicillin derivative, prodrug and bactericide that is readily inactivated by β-lactamases. Bacampicillin hydrochloride is hydrolyzed by carboxylester hydrolases and non-specific esterases in the gastrointestinal wall and plasma to form Ampicillin (HY-B0522), and produces higher levels of Ampicillin in rodents in vivo. Bacampicillin hydrochloride exhibits bactericidal activity against Gram-positive and Gram-negative bacteria. Bacampicillin hydrochloride can be used in studies related to bacterial infections.
    Bacampicillin (hydrochloride)
  • HY-15830
    25,26-Dihydroxyvitamin D3
    25,26-Dihydroxyvitamin D3 (25,26-Dihydroxycholecalciferol) is a dihydroxylated derivative and metabolite of Vitamin D3 (HY-15398). 25,26-Dihydroxyvitamin D3 moderately increases serum calcium levels when the initial serum calcium level is low. 25,26-Dihydroxyvitamin D3 promotes intestinal calcium absorption in vitamin D-deficient rats fed a low-calcium diet. 25,26-Dihydroxyvitamin D3 is applicable to research related to osteomalacia.
    25,26-Dihydroxyvitamin D3
  • HY-N6964
    Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside
    		99.36%
    Quercetin 3-O-β-D-(6''-p-coumaroyl) glucopyranosyl (1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is a flavonoid glycoside present in Ginkgo biloba leaves, with antioxidant activity. Quercetin 3-O-β-D-(6''-p-coumaroyl) glucopyranosyl (1→2)-α-L-rhamnopyranoside serves as the major antioxidant component in Shuxuening Injection.
    Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside
  • HY-131116
    Dihydrojasmonic acid
    		99.92%
    Dihydrojasmonic acid is a plant growth regulator.
    Dihydrojasmonic acid
  • HY-P2023
    Hirugen
    		98.07%
    Hirugen is a derivative of hirudin, an anticoagulant protein found in leeches.
    Hirugen
  • HY-Z16070
    Hydronopol
    		98.09%
    Hydronopol is a saturated alcohol terpene derivative. Hydronopol shows central inhibitory, anticonvulsant, analgesic, anticholinergic and antihypertensive activities. Hydronopol can be used for the researches of neurological and cardiovascular disease.
    Hydronopol
  • HY-146748
    Sorbicillin
    		99.69%
    Sorbicillin, a sorbicillinoid analogue, acts as a potent anti-inflammation agent.
    Sorbicillin
  • HY-W096159
    D-Biotinol
    D-Biotinol is an orally active alcohol analogue of D-Biotin (HY-B0511). D-Biotinol can replace D-Biotin to restore the biotin deficiency induced by egg whites in rats. D-Biotinol can be used for the study of biotin deficiency disorders.
    D-Biotinol
  • HY-78144
    4-Methylsalicylic acid
    		99.97%
    4-Methylsalicylic acid is a methyl derivative of Salicylic acid (HY-B0167). 4-Methylsalicylic acid derivatives inhibit the activity of alkaline phosphatases such as TNAP and IAP. 4-Methylsalicylic acid derivatives exhibit immunosuppressive activity.
    4-Methylsalicylic acid
  • HY-N7138
    2-(Phosphonooxy)benzoic acid
    2-(Phosphonooxy)benzoic acid is a non-acetylated salicylic acid derivative which has the potential for inflammatory disease as well as in analgesic therapy.
    2-(Phosphonooxy)benzoic acid