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Drug Isomer

Drug Isomer

Drug isomers are compounds with the same molecular formula but different atomic arrangements or spatial configurations. They are divided into structural isomers and stereoisomers, and have different biological activities, safety and metabolic characteristics. Drug isomers can be used as drug improvement groups or drug efficacy control groups. For example, Carvedilol has higher bioavailability and better safety than (R)-Carvedilol.

Drug Isomer 관련 제품 (445):

Cat. No. 상품명 효과 Purity Chemical Structure
  • HY-W007140
    2-Hydroxymethyl-5-hydroxypyridine
    		99.67%
    2-Hydroxymethyl-5-hydroxypyridine is isolated from the the matured, ripened and dried seeds of S. lychnophora.
    2-Hydroxymethyl-5-hydroxypyridine
  • HY-W048449
    L-Biotin
    		99.71%
    L-Biotin is the unnatural enantiomer of Biotin (HY-B0511).
    L-Biotin
  • HY-N7199
    (Rac)-Hydnocarpin
    		Control
    (Rac)-Hydnocarpin is a flavonoid isolated from Hydnocarpus anthelminthica, and exhibits moderate cytotoxic on cancer cells.
    (Rac)-Hydnocarpin
  • HY-N1459A
    (S)-Campesterol
    		99.89%
    (S)-Campesterol (5-Ergosten-3β-ol) is a phytosterol (terpenoid) found in the leaves of Plumeria rubra L., form acutifolia (Ait) Woodson.
    (S)-Campesterol
  • HY-17388
    (±)-Huperzine A
    		98.73%
    (±)-Huperzine A is the racemate of (-)-Huperzine A (HY-17387). (-)-Huperzine A is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease.
    (±)-Huperzine A
  • HY-N1765
    L-Praziquanamine
    		99.85%
    L-Praziquanamine is a natural product.
    L-Praziquanamine
  • HY-14307A
    (R)-Necrocide 1
    		99.13%
    (R)-Necrocide 1 (compound (R)-38) a potent anticancer agent. (R)-Necrocide 1 has antiproliferative activity.
    (R)-Necrocide 1
  • HY-15676A
    Idasanutlin (enantiomer)
    		99.18%
    Idasanutlin enantiomer is the isomer of Idasanutlin (HY-15676), and can be used as an experimental control. Idasanutlin (RG7388) is a potent and selective MDM2 antagonist, inhibiting p53-MDM2 binding, with an IC50 of 6 nM.
    Idasanutlin (enantiomer)
  • HY-100741C
    (R,R)-S63845
    		99.32%
    (R,R)-S63845 is the isomer of S63845 (HY-100741), and can be used as an experimental control. S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a Kd of 0.19 nM for human MCL1.
    (R,R)-S63845
  • HY-A0036B
    Bazedoxifene acetate-B
    Bazedoxifene (acetate)-B (TSE-424 (acetate)-B) is the B-crystal form compound of Bazedoxifene acetate (HY-A0036).
    Bazedoxifene acetate-B
  • HY-110258B
    (R,S,R)-ML334
    		Control 98.57%
    (R,S,R)-ML334 is the isomer of ML334 (HY-110258), and can be used as an experimental control. ML334 is a potent, cell permeable activator of NRF2 by inhibition of Keap1-NRF2 protein-protein interaction. ML334 binds to Keap1 Kelch domain with a Kd of 1 μM. ML334 stimulates NRF2 expression and nuclear translocation and induces antioxidant response elements (ARE) activity.
    (R,S,R)-ML334
  • HY-153100
    (R)-mchm5U
    		99.37%
    (R)-mchm5U is a diastereomer of (S)-mchm5U (HY-153100A).
    (R)-mchm5U
  • HY-105559A
    Viquidil hydrochloride
    		99.93%
    Viquidil hydrochloride (Quinotoxine hydrochloride), an isomer of Quinidine, is a cerebral vasodilator agent. Viquidil hydrochloride shows antithrombotic activity.
    Viquidil hydrochloride
  • HY-110155A
    (Rac)-LM11A-31 dihydrochloride
    		99.41%
    (Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a non-peptide p75NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist.
    (Rac)-LM11A-31 dihydrochloride
  • HY-18706
    trans-Tranilast
    		99.63%
    trans-Tranilast (trans-MK-341) is an isomer of Tranilast (HY-B0195), and an anti-allergy agent used in studies of bronchial asthma, allergic rhinitis, and atopic dermatitis.
    trans-Tranilast
  • HY-19489
    (±)-Levomepromazine
    		99.88%
    (±)-Levomepromazine ((±)-Methotrimeprazine) is the racemate of Levomepromazine (HY-B1693).
    (±)-Levomepromazine
  • HY-W236273
    (E)-Ethyl cinnamate
    		98.46%
    (E)-Ethyl cinnamate can be isolated from davana oil.
    (E)-Ethyl cinnamate
  • HY-111772A
    (R)-Elexacaftor
    		99.44%
    (R)-Elexacaftor ((R)-VX-445) is the enantiomer of Elexacaftor (HY-111772). Elexacaftor is an orally active CFTR modulator that targets nucleotide-binding domain 1. Elexacaftor stabilizes misfolded F508del-CFTR protein, enhances its trafficking to the plasma membrane, and significantly improves metabolic stability, thermal stability and ion conductivity. Elexacaftor not only restores chloride transport function in nasal epithelial cells and rescues multiple CFTR mutation subtypes, but also exerts multiplicative synergistic effects with Ivacaftor (HY-13017), and is often used in a triple combination therapy with Tezacaftor (HY-15448). Elexacaftor is widely used in basic and clinical translational research on cystic fibrosis.
    (R)-Elexacaftor
  • HY-W353914
    4α-Hydroxycholesterol
    		99.64%
    4α-Hydroxycholesterol is an isomer of 4β-Hydroxycholesterol (HY-124265). 4α-Hydroxycholesterol has a slight effect on the integrity of lysosomal membranes in mouse primary oligodendrocyte cultures.
    4α-Hydroxycholesterol
  • HY-113336A
    15(R)-HETE
    		99.0%
    15(R)-HETE is an isomer of 15-HETE. 15-HETE is a lipid mediator derived from arachidonic acid and can be used for the study of asthma.
    15(R)-HETE