1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. Early 2 Factor (E2F)
  4. Early 2 Factor (E2F) Inhibitor

Early 2 Factor (E2F) Inhibitor

Early 2 Factor (E2F) Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-16667
    Inhibitor 99.57%
    HLM006474 is a pan E2F inhibitor, which inhibits E2F4 DNA-binding with an IC50 of 29.8 µM in A375 cells.
  • HY-117857
    Inhibitor 99.18%
    MRT00033659 is a potent broad-spectrum kinase inhibitor of CK1 (IC50=0.9 µM for CK1δ) and CHK1 (IC50=0.23 µM). MRT00033659, a pyrazolo-pyridine analogue, induces p53 pathway activation and E2F-1 destabilisation.