iGluR
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iGluR Related Products (457)
Related Products (457)
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D-AP7
0 ImagesCat. No.: HY-107719CAS No.: 81338-23-0D-AP7 is a specific NMDA receptor antagonist with inhibitory activity against epileptiform activity. D-AP7 attenuated neuronal activation in spot activity by reducing the duration and number of exogenously induced bursts. D-AP7 also increased the amplitude of secondary action potentials, which may restore neuronal activity in some epileptiform bursts. D-AP7 showed anxiogenic effects and impaired memory consolidation in passive avoidance learning.
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Bupivacaine (Standard)
0 ImagesBupivacaine (Standard) is the analytical standard of Bupivacaine. This product is intended for research and analytical applications. Bupivacaine is a NMDA receptor inhibitor. Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine can be used for the research of chronic pain.
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rel-GNE 5729
0 ImagesCat. No.: HY-107409ACAS No.: 2088424-87-5
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Ethopropazine hydrochloride (Standard)
0 ImagesSynonyms: Isothazine (Standard)Ethopropazine (hydrochloride) (Standard) is the analytical standard of Ethopropazine (hydrochloride) (HY-107922). This product is intended for research and analytical applications. Ethopropazine (Isothazine) hydrochloride is a potent and selective BChE inhibitor, a poor AChE inhibitor and a non-selective mAChR and NMDA antagonist. Ethopropazine hydrochloride has anticholinergic, antihistamine, antiadrenergic actions and properties. Ethopropazine hydrochloride alleviates thermal hyperalgesia in a dose dependent manner. Ethopropazine hydrochloride can be used for the research of Parkinson’s disease.
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(RS)-AMPA (Standard)
0 ImagesCat. No.: HY-100815BRCAS No.: 77521-29-0Synonyms: (±)-AMPA (Standard)(RS)-AMPA (Standard) is the analytical standard of (RS)-AMPA. This product is intended for research and analytical applications. (RS)-AMPA ((±)-AMPA) is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA does not interfere with binding sites for kainic acid or NMDA receptors.
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CNS-5161 hydrochloride
0 ImagesCat. No.: HY-101809CAS No.: 160756-38-7Synonyms: CNS 5161ACNS-5161 hydrochloride is a novel NMDA ion-channel antagonist that interacts with the NMDA receptor/ion channel site to produce a noncompetitive blockade of the actions of glutamate.
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RPR104632
0 ImagesCat. No.: HY-101600CAS No.: 154106-92-0RPR104632 is a specific antagonist of NMDA receptor, with potent neuroprotective properties.
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Linalool-13C3
0 ImagesCat. No.: HY-N0368S1Linalool-13C3 is 13C labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities.
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Zelquistinel (Standard)
0 ImagesCat. No.: HY-109164RCAS No.: 2151842-64-5Synonyms: AGN-241751 (Standard); GATE-251 (Standard)Zelquistinel (Standard) is the analytical standard of Zelquistinel (HY-109164). This product is intended for research and analytical applications. Zelquistinel (AGN-241751) is the orally active N-methyl-D-aspartate (NMDA) receptor partial agonist used for the research of depression, anxiety and other related psychiatric disorders.
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D-AP5 (Standard)
0 ImagesSynonyms: D-APV (Standard); D-2-Amino-5-phosphonovaleric acid (Standard)D-AP5 (Standard) is the analytical standard of D-AP5 (HY-100714A). This product is intended for research and analytical applications. D-AP5 (D-APV) is a selective and competitive NMDA receptor antagonist with a Kd of 1.4 μM. D-AP5 (D-APV) inhibits the glutamate binding site of NMDA receptors.
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CGP 55802A
0 ImagesCat. No.: HY-123602CAS No.: 152564-63-1CGP 55802A is a novel photoaffinity ligand for in situ labeling of NMDA receptors with high selectivity for the glutamate recognition site.
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Argiotoxin 636
0 ImagesCat. No.: HY-169871CAS No.: 105029-41-2Argiotoxin 636 is a toxin and the non-specific, non-competitive, and potent ionotropic glutamate receptor (iGluR) antagonist. Argiotoxin 636 blocks excitatory synaptic transmission in neurons and has paralysis and muscle relaxation effects. Argiotoxin 636 can be used in the study of nervous system diseases.
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DL-AP5 sodium (Standard)
0 ImagesCat. No.: HY-100714CRCAS No.: 1303993-72-7Synonyms: 2-APV sodium (Standard); DL-2-Amino-5-phosphonovaleric acid sodium (Standard)DL-AP5 (sodium) (Standard) is the analytical standard of DL-AP5 (sodium). This product is intended for research and analytical applications. DL-AP5 (2-APV) sodium is a competitive NMDA (N-methyl-D-aspartate) receptor antagonist. DL-AP5 sodium shows significantly antinociceptive activity. DL-AP5 sodium specifically blocks on channels in the rabbit retina.
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DNQX (Standard)
0 ImagesDNQX (Standard) is the analytical standard of DNQX. This product is intended for research and analytical applications. DNQX (FG 9041), a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively).
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Dizocilpine (Standard)
0 ImagesCat. No.: HY-15084BRCAS No.: 77086-21-6Synonyms: MK-801 (Standard)Dizocilpine (Standard) is the analytical standard of Dizocilpine (HY-15084B). This product is intended for research and analytical applications. Dizocilpine (MK-801), a potent anticonvulsant, is a selective and non-competitive NMDA receptor antagonist, with a Kd of 37.2 nM in rat brain membranes. Dizocilpine acts by binding to a site located within the NMDA associated ion channel and thus prevents Ca2+ flux.
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NBQX disodium (Standard)
0 ImagesCat. No.: HY-15068ARCAS No.: 479347-86-9Synonyms: FG9202 disodium (Standard)NBQX (disodium) (Standard) is the analytical standard of NBQX (disodium). This product is intended for research and analytical applications. NBQX disodium (FG9202 disodium) is a highly selective and competitive AMPA receptor antagonist. NBQX disodium has neuroprotective and anticonvulsant activity.
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Dasolampanel etibutil
0 ImagesCat. No.: HY-123557CAS No.: 503291-52-9Dasolampanel etibutil is an ion-type glutamate receptor 5 (iGluR5) antagonist.
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CX516 (Standard)
0 ImagesCat. No.: HY-10933RCAS No.: 154235-83-3Synonyms: BDP 12 (Standard)CX516 (Standard) is the analytical standard of CX516 (HY-10933). This product is intended for research and analytical applications. CX516 (BDP 12) is an ampaKine and acts as an AMPA receptor positive allosteric modulator for the research of Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).
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SYM 2081 (Standard)
0 ImagesCat. No.: HY-101310RCAS No.: 31137-74-3SYM 2081 (Standard) is the analytical standard of SYM 2081 (HY-101310). This product is intended for research and analytical applications. SYM 2081 is a kainate receptor agonist. SYM 2081 is a substrate of EAAT1 (Km of 54 μM). SYM 2081 inhibits EAAT2-mediated glutamate transport (Kb is 3.4 μM in Xenopus oocytes), modulates Apoptotic signaling pathways (increases Bcl-2 and decreases Bax/caspase-3 expression). SYM 2081 exhibits neuroprotective activity. SYM 2081 can be used in the study of hypoxic-ischemic brain damage and inflammatory or neuropathic pain.
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Memantine lactose adduct
0 ImagesCat. No.: HY-137064CAS No.: 1159637-28-1Memantine lactose adduct is a lactose adduct of Memantine (HY-B0591) and an intermediate in the synthesis of adamantane amine antibiotics.
