Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11126)
Related Products (11126)
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Sodium-dodecyl sulfate-d25
0 ImagesSynonyms: Sodium lauryl sulfate-d25; Laurylsulfuric acid-d25 sodium saltSodium-dodecyl sulfate-d25 is a deuterium labeled Sodium dodecyl sulfate. Sodium dodecyl sulfate is the most widely used of the anionic alkyl sulfate surfactants.
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Perylene-d12
0 ImagesSynonyms: Peri-dinaphthalene-d12Perylene-d12 is the deuterium labeled Perylene.
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1-Methylnicotinamide-13C,d3 iodide
0 ImagesCat. No.: HY-W009418SPurity: 98.63%1-Methylnicotinamide-13C,d3 (iodide) is the 13C- and deuterium labeled 3-Carbamoyl-1-methylpyridin-1-ium iodide.
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2-Bromonaphthalene-d7
0 Images2-Bromonaphthalene-d7 is the deuterium labeled 2-Bromonaphthalene.
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Adipic acid-13C6
0 ImagesSynonyms: Hexanedioic acid-13C6Adipic acid-13C6 (Hexanedioic acid-13C6) is the 13C labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc.
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L-Threonine-13C4,15N
0 ImagesL-Threonine-13C4,15N is the 13C- and 15N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed.
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Spermidine-d6 trihydrochloride
0 ImagesCat. No.: HY-W709575Purity: 98.0%Spermidine-d6 trihydrochloride is the deuterium labeled Spermidine-d6 (trihydrochloride) (HY-W709575).
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TMA chloride-d12 chloride
0 ImagesSynonyms: Tetramethylammonium chloride-d12 chlorideTetramethylammonium-d12 (chloride) is the deuterium labeled Tetramethylammonium chloride.
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Sodium propionate-13C3
0 ImagesSodium propionate-13C-3 is the 13C-labeled Propionate sodium (HY-B1773A). Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease.
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Rapamycin-d3
0 ImagesCat. No.: HY-10219SCAS No.: 392711-19-2Synonyms: Sirolimus-d3; AY-22989-d3; NSC 226080-d3Rapamycin-d3 (Sirolimus-d3; AY-22989-d3; NSC 226080-d3) is the deuterated-labeled Rapamycin (HY-10219). Rapamycin (Sirolimus; AY 22989) is a potent and specific blood-brain barrier-transmissible mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin is a molecular glue that binds FKBP12 and mTOR proteins together, thereby inhibiting mTOR kinase activity. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.
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6-Hydroxy Melatonin-d4
0 ImagesCat. No.: HY-132425SCAS No.: 69533-61-56-Hydroxy Melatonin-d4 is the deuterium labeled 6-Hydroxy Melatonin.
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LysoPC(14:0/0:0)-d7
0 ImagesCat. No.: HY-113123S1Synonyms: 14:0 Lyso PC-d7; 1-myristoyl-sn-glycero-3-phosphatidylcholine-d7LysoPC(14:0/0:0)-d7 (14:0 Lyso PC-d7) is deuterium labeled LysoPC(14:0/0:0). LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect.
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Darolutamide-d4
0 ImagesSynonyms: ODM-201-d4; BAY-1841788-d4Darolutamide-d4 (ODM-201-d4) is deuterium labeled Darolutamide (HY-16985). Darolutamide (ODM-201) is an orally active competitive androgen receptor (AR) antagonist, with a Ki of 11 nM for rat wild-type AR (wtAR) and an IC50 of 26 nM for human wild-type AR (hAR)-mediated transcriptional activation. Darolutamide inhibits testosterone-induced AR nuclear translocation and transcriptional activation. Darolutamide exerts selective effects on AR-positive cells by inhibiting AR-dependent signaling pathways, and its active metabolite retains full antagonistic activity against AR mutants. Darolutamide can be used for the research of prostate cancer, including androgen receptor-dependent prostate cancer.
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Tizanidine-d4
0 ImagesTizanidine-d4 is the deuterium labeled Tizanidine (HY-B0194). Tizanidine, a skeletal muscle relaxant, is an orally effective central α2-adrenoceptor agonist (IC50 = 6.9 nmol). Tizanidine primarily exerts muscle relaxation effects by inhibiting the release of excitatory amino acids (glutamate and aspartate) from the presynaptic terminals of spinal cord interneurons. Tizanidine has anti-injury activity and can inhibit gastrointestinal (GI) transport. Tizanidine can inhibit the proliferation, migration, and invasion of lung cancer cells and induce cell apoptosis by upregulating Nischarin and inhibiting the AKT and Wnt3a/β-catenin signaling pathways. Tizanidine can be used to treat spasticity caused by diseases such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI).
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Mycophenolate Mofetil-d4
0 ImagesMycophenolate Mofetil-d4 is the deuterium labeled Mycophenolate Mofetil. Mycophenolate mofetil (RS 61443; TM-MMF) hydrochloride is an orally active antimetabolic immunosuppressant with antiproliferative and anti-inflammatory properties. Mycophenolate mofetil hydrochloride significantly inhibits the production of B, T lymphocytes and the proliferation of smooth muscle cells by selectively blocking the de novo purine synthesis pathway. Mycophenolate mofetil hydrochloride effectively reduces adventitial inflammation, medial necrosis and intimal thickening in rat aortic allografts, and decreases the number of lymphocytes expressing the IL-2 receptor, thereby delaying xenograft rejection. Mycophenolate mofetil hydrochloride shows certain toxicity in a hamster-to-rat limb xenotransplantation model when used in combination with FK506 (HY-13756). Mycophenolate mofetil hydrochloride is widely used in studies related to allograft arteriosclerosis (chronic rejection).
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Calcifediol-d3
0 ImagesSynonyms: 25-Hydroxy Vitamin D3-d3Calcifediol-d3 is a deuterium labeled Calcifediol. Calcifediol, is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels.
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Diclofenac-d4
0 ImagesDiclofenac-d4 is the deuterium labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.
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Oxaloacetic acid-13C4
0 ImagesSynonyms: 2-Oxosuccinic acid-13C4Oxaloacetic acid-13C4 is the 13C-labeled Oxaloacetic acid. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis.
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L-Carnitine-d9 chloride
0 ImagesSynonyms: (R)-Carnitine-d9 chloride; Levocarnitine-d9 chlorideL-Carnitine-d9 (chloride)e is the deuterium labeled L-Carnitine chloride. L-Carnitine chloride, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine chloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine chloride is an antioxidant. L-Carnitine chloride can ameliorate metabolic imbalances in many inborn errors of metabolism.
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Abscisic acid-d6
0 ImagesSynonyms: (S)-(+)-Abscisic acid-d6; ABA-d6Abscisic acid-d6 is deuterium labeled Abscisic acid. Abscisic acid inhibits proton pump (H+-ATPase).
