Reference Standards
Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.
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Productos relacionados con Reference Standards (11772)
Productos relacionados con (11772)
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Chloroxine (Standard)
0 ImagesChloroxine (Standard) is the analytical standard of Chloroxine. This product is intended for research and analytical applications. Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp.
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Didesmethyl cariprazine (Standard)
0 ImagesDidesmethyl cariprazine (Standard) is the analytical standard of Didesmethyl cariprazine (HY-100658). This product is intended for research and analytical applications. Didesmethyl cariprazine is an orally active, BBB-permeable metabolite of Cariprazine (HY-14763). Didesmethyl cariprazine is a partial agonist at the D2 and D3 receptors, full agonist at the 5-HT1A receptor, and antagonist at the human 5-HT2B receptor (Ki: 1.41 nM (human D2L), 0.056 nM (human D3), 1.7 nM (human 5-HT1A), 0.52 nM (human 5-HT2B)). Didesmethyl cariprazine dose-dependently inhibits the spontaneous activity of rat midbrain dopaminergic neurons.
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AU1235 (Standard)
0 ImagesReferencia número: HY-101867RNo. CAS: 1338780-86-1AU1235 (Standard) is the analytical standard of AU1235 (HY-101867). This product is intended for research and analytical applications. AU1235, an adamantyl urea, is a potent MmpL3 inhibitor. The Mycobacterium tuberculosis protein MmpL3 performs an essential role in cell wall synthesis, since it effects the transport of trehalose monomycolates across the inner membrane.
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IKK 16 (Standard)
0 ImagesIKK 16 (Standard) is the analytical standard of IKK 16. This product is intended for research and analytical applications. IKK 16 hydrochloride is an orally active IKK inhibitor. IKK 16 hydrochloride shows IC50s of 40 nM, 70 nM, 200 nM, and 50 nM for IKK2, IKK complex, IKK1, and LRRK 2, respectively. IKK 16 hydrochloride is also a pan-PKD inhibitor, inhibiting PKD1, PKD2, and PKD3 with IC50s of 153.9, 115, and 99.7 nM, respectively. IKK 16 hydrochloride is also an ABCB1 inhibitor, interfering with the binding of ABCB1 to its substrates. IKK 16 hydrochloride protects against LPS (HY-D1056)-induced multiple organ dysfunction by reducing the acute inflammatory response induced by endotoxin exposure. IKK 16 hydrochloride can restore renal function and alleviate fibrosis in acute kidney injury. IKK 16 hydrochloride attenuates cardiac dysfunction associated with polymicrobial sepsis in mice with type 2 diabetes mellitus (T2DM) by inhibiting the NF-κB pathway.
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NG 52 (Standard)
0 ImagesSynonyms: Compound 52 (Standard)NG 52 (Standard) is the analytical standard of NG 52. This product is intended for research and analytical applications. NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC50s of 7 μM and 2 μM, respectively. NG 52 also inhibits the activity of phosphoglycerate kinase 1 (PGK1) with an IC50 of 2.5 μM. NG 52 is inactive against yeast kinases Kin28p, Srb10, and Cak1p.
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Taniborbactam hydrochloride (Standard)
0 ImagesReferencia número: HY-109124ARNo. CAS: 2244235-49-0Synonyms: VNRX-5133 hydrochloride (Standard)Taniborbactam hydrochloride (Standard) is the analytical standard of Taniborbactam (hydrochloride) (HY-109124A). This product is intended for research and analytical applications. Taniborbactam hydrochloride (VNRX-5133 hydrochloride) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC50s of 8-530 nM. Taniborbactam hydrochloride has IC50s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam hydrochloride is against Gram-negative bacteria.
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Ciforadenant (Standard)
0 ImagesSynonyms: CPI-444 (Standard); V81444 (Standard)Ciforadenant (Standard) is the analytical standard of Ciforadenant (HY-101978). This product is intended for research and analytical applications. Ciforadenant (CPI-444) is a potent, orally active and selective adenosine A2A receptor (A2AR) antagonist, which induces antitumor responses.
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Militarine (Standard)
0 ImagesReferencia número: HY-122308RNo. CAS: 58139-23-4Militarine (Standard) is the analytical standard of Militarine (HY-122308). This product is intended for research and analytical applications. Militarine is a plant growth inhibitor and anti-inflammatory agent. Militarine inhibits the elongation of radicles and hypocotyls in seedlings of lettuce, Italian ryegrass and timothy grass. Militarine alleviates PM2.5-induced inflammatory injury and inhibits cell migration in human alveolar epithelial A549 cells by inhibiting the NF-κB signaling pathway, reducing oxidative stress and the release of inflammatory factors. Militarine can be used in studies related to PM2.5-induced pulmonary diseases.
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Cornuside (Standard)
0 ImagesReferencia número: HY-N0631RNo. CAS: 131189-57-6Cornuside (Standard) is the analytical standard of Cornuside (HY-N0631). This product is intended for research and analytical applications. Cornuside is an iridoid glycoside with anti-allergic, anti-inflammatory, and neuroprotective activities. Cornuside exerts anti-allergic activity by downregulating the p38 MAPK, JNK, and NF-κB signaling pathways, and inhibits IgE-mediated histamine release from mast cells. Cornuside improves cognitive impairment in mice by inhibiting BACE1 activity (IC50 = 55.84 μg/mL) and enhancing ChAT activity. Cornuside inhibits LPS (HY-D1056)-induced inflammatory mediators, including iNOS, COX-2, PGE2, TNF-α, IL-6, and IL-1β, by suppressing NF-κB activation.
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Copper diacetate monohydrate (Standard)
0 ImagesReferencia número: HY-W075783RNo. CAS: 6046-93-1Synonyms: Acetic acid, copper(2+) salt, monohydrate (Standard)Copper(II)acetatemono hydrate (Standard) is the analytical standard of Copper(II)acetatemono hydrate. This product is intended for research and analytical applications.
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TAK-243 (Standard)
0 ImagesReferencia número: HY-100487RNo. CAS: 1450833-55-2Synonyms: MLN7243 (Standard)TAK-243 (Standard) is the analytical standard of TAK-243 (HY-100487). This product is intended for research and analytical applications. TAK-243 (MLN7243) is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor (IC50=1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global protein ubiquitination. TAK-243 (MLN7243) induces endoplasmic reticulum (ER) stress, abrogates NF-κB pathway activation and promotes apoptosis.
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(S)-N-methyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride (Standard)
0 ImagesReferencia número: HY-Z10179RNo. CAS: 157166-71-7(S)-N-methyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride (Standard) is the analytical standard of (S)-N-methyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride. This product is intended for research and analytical applications.
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Mesdopetam hemitartrate (Standard)
0 ImagesReferencia número: HY-109150ARNo. CAS: 2562346-14-7Synonyms: IRL790 hemitartrate (Standard)Mesdopetam hemitartrate (Standard) is the analytical standard of Mesdopetam (hemitartrate) (HY-109150A). This product is intended for research and analytical applications. Mesdopetam (IRL790) hemitartrate is a dopamine D3 receptor antagonist (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor) with psychomotor stabilizing properties. Mesdopetam hemitartrate is used for the research of motor and psychiatric complications in ParKinson disease.
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L-368,899 hydrochloride (Standard)
0 ImagesReferencia número: HY-108677RNo. CAS: 160312-62-9L-368,899 hydrochloride (Standard) is the analytical standard of L-368,899 hydrochloride (HY-108677). This product is intended for research and analytical applications. L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368,899 hydrochloride used as a tocolytic agent.
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680C91 (Standard)
0 ImagesReferencia número: HY-108681RNo. CAS: 163239-22-3680C91 (Standard) is the analytical standard of 680C91 (HY-108681). This product is intended for research and analytical applications. 680C91 is an orally active, selective tryptophan 2,3-dioxygenase (TDO) inhibitor with a Ki of 51 nM. TDO is the key enzyme of tryptophan catabolism. 680C91 can be used for the research of cancer immunotherapy and Alzheimer’s Disease.
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Perospirone hydrochloride (Standard)
0 ImagesReferencia número: HY-B0731RNo. CAS: 129273-38-7Synonyms: SM-9018 (Standard)Perospirone (hydrochloride) (Standard) is the analytical standard of Perospirone (hydrochloride). This product is intended for research and analytical applications. Perospirone hydrochloride (SM-9018) is an orally active antagonist of 5-HT2A receptor (Ki of 0.6 nM) and dopamine D2 receptor (Ki of 1.4 nM). Perospirone hydrochloride is also a partial agonist of 5-HT1A receptor (Ki of 2.9 nM). Perospirone hydrochloride is an atypical antipsychotic agent and has the potential for schizophrenic disease research.
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14,15-Dehydro budesonide (Standard)
0 ImagesReferencia número: HY-Z3488RNo. CAS: 131918-64-4(6aR,6bS,7S,8aS,8bS,11aR,12bR)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10-propyl-6a,6b,7,8,8a,8b,11a,12b-octahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity） (Standard) is the analytical standard of (6aR,6bS,7S,8aS,8bS,11aR,12bR)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10-propyl-6a,6b,7,8,8a,8b,11a,12b-octahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity）. This product is intended for research and analytical applications.
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N-(2-(Diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide (Standard)
0 ImagesReferencia número: HY-W042154RNo. CAS: 356068-86-5N-(2-(Diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide (Standard) is the analytical standard of N-(2-(Diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide (HY-W042154). This product is intended for research and analytical applications.
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Ixazomib (Standard)
0 ImagesSynonyms: MLN2238 (Standard)Ixazomib (Standard) is the analytical standard of Ixazomib. This product is intended for research and analytical applications. Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM).
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4-Hydroxy-5-methoxyisophthalaldehyde (Standard)
0 ImagesReferencia número: HY-W112784RNo. CAS: 2931-90-0
