Reference Standards
Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.
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Reference Standards Related Products (11771)
Related Products (11771)
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JGB1741 (Standard)
0 ImagesCat. No.: HY-111329RCAS No.: 1256375-38-8Synonyms: ILS-JGB-1741 (Standard)JGB1741 (Standard) is the analytical standard of JGB1741 (HY-111329). This product is intended for research and analytical applications. JGB1741 (ILS-JGB-1741) is a potent and specific SIRT1 activity inhibitor with an IC50 of ～15 μM. JGB1741 is a weak SIRT2 and SIRT3 inhibitor with an all IC50>100 μM. JGB1741 increases the acetylated p53 levels leading to p53-mediated apoptosis with modulation of Bax/Bcl2 ratio, cytochrome c release and PARP cleavage. JGB1741 has the potential for breast cancer research.
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Dinaciclib (Standard)
0 ImagesSynonyms: SCH 727965 (Standard)Dinaciclib (Standard) is the analytical standard of Dinaciclib (HY-10492). This product is intended for research and analytical applications. Dinaciclib (SCH 727965) is a potent inhibitor of CDK, with IC50s of 1 nM, 1 nM, 3 nM, and 4 nM for CDK2, CDK5, CDK1, and CDK9, respectively.
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MRT68921 dihydrochloride (Standard)
0 ImagesMRT68921 (dihydrochloride) (Standard) is the analytical standard of MRT68921 (dihydrochloride) (HY-100006A). This product is intended for research and analytical applications. MRT68921 dihydrochloride is a potent NUAK1/ULK1 dual inhibitor. MRT68921 dihydrochloride inhibits ULK1 and ULK2 with IC50 values of 2.9 nM and 1.1 nM, respectively. MRT68921 dihydrochloride can block cells autophagy and kill tumor cells by breaking the balance of oxidative stress signals. MRT68921 dihydrochloride can inhibit cell proliferation and induce ROS production and apoptosis. MRT68921 dihydrochloride can be used for the research of cancer, such as breast cancer.
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Rhein 8-O-β-D-Glucopyranoside (Standard)
0 ImagesCat. No.: HY-N6082RCAS No.: 34298-86-7Rhein 8-O-β-D-Glucopyranoside (Standard) is the analytical standard of Rhein 8-O-β-D-Glucopyranoside (HY-N6083). This product is intended for research and analytical applications. Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection.
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4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide (Standard)
0 Images4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide (Standard) is the analytical standard of 4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide. This product is intended for research and analytical applications.
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Almorexant (Standard)
0 ImagesCat. No.: HY-10805RCAS No.: 871224-64-5Synonyms: ACT 078573 (Standard)Almorexant (Standard) is the analytical standard of Almorexant. This product is intended for research and analytical applications. Almorexant (ACT 078573) is an orally active, potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM (OX1) and 0.17 nM (OX2), respectively. Almorexant reversibly blocks signaling of orexin-A and orexin-B peptides. Almorexant totally blocked the intracellular Ca2+ signal pathway. Almorexant stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis .
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Ethyl β-D-glucopyranoside (Standard)
0 ImagesEthyl β-D-glucopyranoside (compound 10) is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS-
TM5441 (Standard)
0 ImagesTM5441 (Standard) is the analytical standard of TM5441 (HY-101761). This product is intended for research and analytical applications. TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM and induces intrinsic apoptosis in several human cancer cell lines. TM5441 attenuates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence.
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Morpholine-4-carbaldehyde (Standard)
0 ImagesCat. No.: HY-W015887RCAS No.: 4394-85-8Synonyms: N-Formylmorpholine (Standard)Morpholine-4-carbaldehyde (Standard) is the analytical standard of Morpholine-4-carbaldehyde. This product is intended for research and analytical applications.
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Paliperidone (Standard)
0 ImagesSynonyms: 9-Hydroxyrisperidone (Standard)Paliperidone (Standard) is the analytical standard of Paliperidone. This product is intended for research and analytical applications. Paliperidone (9-Hydroxyrisperidone), the major active metabolite of Risperidone, is a dopamine D2 antagonist and 5-HT2A antagonist. Paliperidone is also active as an antagonist at α1 and α2 adrenergic receptors and H1-histaminergic receptors. Paliperidone, a antipsychotic agent, shows efficacy against schizophrenia.
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Indoramin (Standard)
0 ImagesCat. No.: HY-12760RCAS No.: 26844-12-2Synonyms: Indoramine (Standard); Wy 21901 (Standard)Indoramin (Standard) is the analytical standard of Indoramin. This product is intended for research and analytical applications. Indoramin is an orally active antihypertensive agent. Indoramin is also selective for the α1A-adrenoceptor.
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Medetomidine hydrochloride (Standard)
0 ImagesSynonyms: MPV785 (Standard)Medetomidine (hydrochloride) (Standard) is the analytical standard of Medetomidine (hydrochloride). This product is intended for research and analytical applications. Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels.
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Nimorazole (Standard)
0 ImagesNimorazole (Standard) is the analytical standard of Nimorazole. This product is intended for research and analytical applications. Nimorazole (K-1900), a 2-nitroimidazole, is a hypoxic cell-radiation sensitizer. Nimorazole has anti-infective and anti-protozoal against trichomoniasis. Nimorazole has the potential for head and neck cancer.
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1,3-Dimethyladamantane (Standard)
0 ImagesCat. No.: HY-W100063RCAS No.: 702-79-41,3-Dimethyladamantane (Standard) is the analytical standard of 1,3-Dimethyladamantane. This product is intended for research and analytical applications.
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Benfotiamine (Standard)
0 ImagesSynonyms: S-Benzoylthiamine O-monophosphate (Standard)Benfotiamine (Standard) is the analytical standard of Benfotiamine. This product is intended for research and analytical applications. Benfotiamine (S-Benzoylthiamine O-monophosphate) is a vitamin B1 derivative that exhihibits potent antioxidative and anti-inflammatory activity. Benfotiamine can be used for the research of various secondary diabetic complications. Benfotiamine also can be used in infectious diseases such as HIV and COVID-19.
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GATA4-NKX2-5-IN-1 (Standard)
0 ImagesCat. No.: HY-103484RCAS No.: 544681-96-1GATA4-NKX2-5-IN-1 (Standard) is the analytical standard of GATA4-NKX2-5-IN-1 (HY-103484). This product is intended for research and analytical applications. GATA4-NKX2-5-IN-1 (Compound 3) dose-dependently inhibits the GATA4–NKX2-5 transcriptional synergy with an IC50 of 3 μM. GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression.
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2-Methoxyphenothiazine (Standard)
0 ImagesSynonyms: 2-Methoxy-10H-phenothiazine (Standard)2-Methoxyphenothiazine (2-Methoxy-10H-phenothiazine) is a biochemical reagent that can be used in research fields such as life sciences or organic chemistry.
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sec-Butyl 4-methylbenzenesulfonate (Standard)
0 ImagesCat. No.: HY-W017654RCAS No.: 715-11-7sec-Butyl 4-methylbenzenesulfonate (Standard) is the analytical standard of sec-Butyl 4-methylbenzenesulfonate. This product is intended for research and analytical applications.
