1. GPCR/G Protein
    Neuronal Signaling
  2. Dopamine Receptor
  3. A68930

A68930 

Cat. No.: HY-120687
Handling Instructions

A68930, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis.

For research use only. We do not sell to patients.

A68930 Chemical Structure

A68930 Chemical Structure

CAS No. : 130465-45-1

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Description

A68930, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis[1].

IC50 & Target

D1 Receptor

 

In Vitro

A68930 (1 μM; 5-60 minutes; 16HBE14o- or NCI-H292 cells) significantly increases phosphorylation of cAMP response element binding (CREB) protein[1].
A68930 (1 μM; 48 hours; NCI-H292 cells) induces MUC5AC mRNA expression and increases the mRNA data of MUC5AC and MUC5AC protein expression[1].
A68930 (1 μM; 20 minutes; NCI-H292 cells) significantly increases intracellular cAMP levels[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: 16HBE14o- or NCI-H292 cells
Concentration: 1 μM
Incubation Time: 5~60 minutes
Result: Significantly increased phosphorylation of CREB.

RT-PCR[1]

Cell Line: NCI-H292 cells
Concentration: 1 μM
Incubation Time: 48 hours
Result: Induced MUC5AC mRNA expression.

Immunofluorescence[1]

Cell Line: NCI-H292 cells
Concentration: 1 μM
Incubation Time: 48 hours
Result: The mRNA data of MUC5AC, MUC5AC protein expression were increased.
Molecular Weight

271.31

Formula

C₁₆H₁₇NO₃

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
A68930
Cat. No.:
HY-120687
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