1. GPCR/G Protein
    Neuronal Signaling
  2. Dopamine Receptor
  3. A68930 hydrochloride

A68930 hydrochloride 

Cat. No.: HY-103431
Handling Instructions

A68930 hydrochloride, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis.

For research use only. We do not sell to patients.

A68930 hydrochloride Chemical Structure

A68930 hydrochloride Chemical Structure

CAS No. : 130465-39-3

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Description

A68930 hydrochloride, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis[1].

IC50 & Target[1]

D1 Receptor

 

In Vitro

A68930 hydrochloride (1 μM; 5-60 minutes; 16HBE14o- or NCI-H292 cells) significantly increases phosphorylation of cAMP response element binding (CREB) protein[1].
A68930 hydrochloride (1 μM; 48 hours; NCI-H292 cells) induces MUC5AC mRNA expression and increases the mRNA data of MUC5AC and MUC5AC protein expression[1].
A68930 hydrochloride (1 μM; 20 minutes; NCI-H292 cells) significantly increases intracellular cAMP levels[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: 16HBE14o- or NCI-H292 cells
Concentration: 1 μM
Incubation Time: 5~60 minutes
Result: Significantly increased phosphorylation of CREB.

RT-PCR[1]

Cell Line: NCI-H292 cells
Concentration: 1 μM
Incubation Time: 48 hours
Result: Induced MUC5AC mRNA expression.

Immunofluorescence[1]

Cell Line: NCI-H292 cells
Concentration: 1 μM
Incubation Time: 48 hours
Result: The mRNA data of MUC5AC, MUC5AC protein expression were increased.
Molecular Weight

307.77

Formula

C₁₆H₁₈ClNO₃

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
A68930 hydrochloride
Cat. No.:
HY-103431
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