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ABT-325

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Based on 1 Customer Validation

ABT-325 is a humanized antibody expressed in CHO that targets IL-18. ABT-325 has a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 146.28 kDa. The isotype control for ABT-325 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

For research use only. We do not sell to patients.

  • Purity: 99.75%
  • Molecular Weight:146.28 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for ABT-325
  • Experimental Validation Results for ABT-325
  • ABT-325 Chemical Structure
    ABT-325 Chemical Structure
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ABT-325 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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100 mg

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  • 1/16

    Flow Cytometry analysis of A431 cells labelling ABT-325 (red) with ABT-325 Antibody (anti-CD4) (HY-P990312). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃.Human IgG1 kappa isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Immobilized N-His-SUMO-Hu-IL-18 can bind ABT-325. The EC50 for this effect is 108.7 ng/mL.

  • ABT-325 Chemical Structure
    1/16
  • ABT-325
  • Flow Cytometry analysis of A431 cells labelling ABT-325 (red) with ABT-325 Antibody (anti-CD4) (HY-P990312). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃.Human IgG1 kappa isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Immobilized N-His-SUMO-Hu-IL-18 can bind ABT-325. The EC50 for this effect is 108.7 ng/mL.