2. Cytoskeleton
  3. Integrin
  4. Anti-CD11a/LFA-1α Antibody (R7-1)

Anti-CD11a/LFA-1α Antibody (R7-1) is a kind of mouse IgG1 chimeric antibody inhibitor, targeting to human CD11a/LFA-1α. Anti-CD11a/LFA-1α Antibody (R7-1) can neutralize LFA-1α (lymphocyte function-associated antigen 1 alpha) also known as integrin alpha L chain and CD11a. Anti-CD11a/LFA-1α Antibody (R7-1) can be used for the research of inflammation.

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Anti-CD11a/LFA-1α Antibody (R7-1)

Anti-CD11a/LFA-1α Antibody (R7-1) Estructura química

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Anti-CD11a/LFA-1α Antibody (R7-1) Related Antibodies

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Descripciòn

Anti-CD11a/LFA-1α Antibody (R7-1) is a kind of mouse IgG1 chimeric antibody inhibitor, targeting to human CD11a/LFA-1α. Anti-CD11a/LFA-1α Antibody (R7-1) can neutralize LFA-1α (lymphocyte function-associated antigen 1 alpha) also known as integrin alpha L chain and CD11a. Anti-CD11a/LFA-1α Antibody (R7-1) can be used for the research of inflammation[1].

Isotype

Mouse IgG1 kappa
Recommend Isotype Controls
Species Reactivity

Human
IC50 & Target

CD11a/LFA-1α
In Vivo

Anti-CD11a/LFA-1α Antibody (R7-1) (1 mg/kg, i.v., 0.5 h before thioglycollate) increases blood neutrophil in the adult rabbits 6 h after instillation of thioglycollate[1].
Anti-CD11a/LFA-1α Antibody (R7-1) (1 mg/kg, i.v., 0.5 h before thioglycollate) reduces peritoneal accumulation of leukocytes in adult and neonatal rabbits 6 h after instillation of thioglycollate[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult and neonatal 6 h after instillation of thioglycollate[1]
Dosage: 1 mg/kg
Administration: Intravenously injection, 0.5 h before thioglycollate
Result: Increased blood neutrophili in adult rabbits.
Reduced peritoneal accumulation of leukocytes.
Gene ID

3683  [NCBI]

Accession
Application

Functional assays; Flow cytometry
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Peso molecular

150 kDa

SMILES

[Anti-CD11a/LFA-1aAntibody (R7-1)]
Formulation

Please refer to the lot-specific COA for specific buffer information.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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Anti-CD11a/LFA-1α Antibody (R7-1) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-CD11a/LFA-1α Antibody (R7-1)IntegrinCD11aLFA-1αNeutrophilLeukocytesInhibitorinhibitorinhibit

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Nombre del producto:
Anti-CD11a/LFA-1α Antibody (R7-1)
Cat. No.:
HY-P990871
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