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Cat. No.: HY-189508

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Antimalarial agent-72

Antimalarial agent-72 is a ring-contracted Artemisinin (HY-B0094) derivative. Antimalarial agent-72 can be used to synthesize the hydrophobic tag (Hyt) degrader HDAC6 degrader-6 (HY-189299). Antimalarial agent-72 can be used for research on leukemia and malaria.

For research use only. We do not sell to patients.

CAS No.: 164200-23-1
Formula: C₁₅H₂₂O₆
Molecular Weight:298.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Antimalarial agent-72 Chemical Structure

CAS No.: 164200-23-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 164200-23-1
Molecular Weight 298.33
Formula C₁₅H₂₂O₆
SMILES

OC([C@@]1(C)O[C@]2([H])O[C@@]3(C)CC[C@]4([H])[C@@]2(OO3)[C@@]1([H])CC[C@H]4C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wang C, et al. Artemisinin-derived hydrophobic tags: structural modification and structure-activity relationship exploration of HDAC6/1 targeting degraders with potent antileukemic efficacy. Bioorganic chemistry. 2026 Oct 05;181:110275.

[2]. Venugopalan B, et al. Antimalarial activity of novel ring-contracted artemisinin derivatives. J Med Chem. 1995 May 26;38(11):1922-7.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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