AS601245 (Standard)

AS601245 (Standard) is the analytical standard of AS601245 (HY-11010). This product is intended for research and analytical applications. AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein Kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein Kinases. Neuroprotective properties.

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  • CAS No.: 345987-15-7
  • Formule: C20H16N6S
  • Masse moléculaire:372.45
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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