AS601245 (Standard)
AS601245 (Standard) is the analytical standard of AS601245 (HY-11010). This product is intended for research and analytical applications. AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein Kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein Kinases. Neuroprotective properties.
For research use only. We do not sell to patients.
- CAS No.: 345987-15-7
- Formula: C20H16N6S
- Molecular Weight:372.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 345987-15-7
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Molecular Weight 372.45
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Formula C20H16N6S
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SMILES
N#CC(C1=CC=NC(NCCC2=CC=CN=C2)=N1)C3=NC4=CC=CC=C4S3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)