AS601245 (Standard)
AS601245 (Standard) is the analytical standard of AS601245 (HY-11010). This product is intended for research and analytical applications. AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein Kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein Kinases. Neuroprotective properties.
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- CAS No.: 345987-15-7
- Formule: C20H16N6S
- Masse moléculaire:372.45
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 345987-15-7
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Masse moléculaire 372.45
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Formule C20H16N6S
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SMILES
N#CC(C1=CC=NC(NCCC2=CC=CN=C2)=N1)C3=NC4=CC=CC=C4S3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)