Butyrylcarnitine
Based on 1 publication(s) in Google Scholar
Butyrylcarnitine is an endogenous metabolite found in plasma. Elevated levels of Butyrylcarnitine are closely associated with abnormalities in lipid and energy metabolism. Butyrylcarnitine can serve as a diagnostic and prognostic indicator for certain diseases, such as heart failure and head and neck cancer.
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- Reinheit: 99.96%
- CAS. Nr.: 25576-40-3
- Formel: C11H21NO4
- Molecular Weight:231.29
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Publications Citing Use of MedChemExpress (MCE) Butyrylcarnitine
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Biologische Aktivität
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Human Endogenous Metabolite |
Butyrylcarnitine (0-10 mM; 72 h) promotes cell proliferation in a dose-dependent manner within a certain concentration range in the HN30 cell line[2].
Butyrylcarnitine (100 µM; 0-96 h) can enhance the proliferation, migration and invasion abilities of HN30 cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HN30 cells
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Concentration:0, 1 nM, 10 nM, 100 nM, 1 µM, 10 µM, 100 µM, 1 mM, and 10 mM
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Incubation Time:72 h
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Result:Promoted cell proliferation in a dose-dependent manner within a certain concentration range. The cell viability was significantly enhanced at concentrations up to 100 µM, while higher concentration (10 mM) led to a reduction in cell viability.
Chemical Information
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CAS. Nr. 25576-40-3
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Appearance Solid
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Molecular Weight 231.29
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Formel C11H21NO4
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Color White to off-white
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SMILES
CCCC(O[C@H](CC([O-])=O)C[N+](C)(C)C)=O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
Lösungsmittel & Löslichkeit
H2O : ≥ 100 mg/mL (432.36 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (432.36 mM); Clear solution; Need ultrasonic
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
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- Italian - IT (251 KB)
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- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Cheng ML, et al. Metabolic disturbances identified in plasma are associated with outcomes in patients with heart failure: diagnostic and prognostic value of metabolomics. J Am Coll Cardiol. 2015 Apr 21;65(15):1509-20. [Content Brief]
[2]. Li Y, et al. Causal association between blood metabolites and head and neck cancer: butyrylcarnitine identified as an associated trait for cancer risk and progression. Hereditas. 2025 Mar 14;162(1):36. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.3236 mL | 21.6179 mL | 43.2358 mL | 108.0894 mL |
| 5 mM | 0.8647 mL | 4.3236 mL | 8.6472 mL | 21.6179 mL | |
| 10 mM | 0.4324 mL | 2.1618 mL | 4.3236 mL | 10.8089 mL | |
| 15 mM | 0.2882 mL | 1.4412 mL | 2.8824 mL | 7.2060 mL | |
| 20 mM | 0.2162 mL | 1.0809 mL | 2.1618 mL | 5.4045 mL | |
| 25 mM | 0.1729 mL | 0.8647 mL | 1.7294 mL | 4.3236 mL | |
| 30 mM | 0.1441 mL | 0.7206 mL | 1.4412 mL | 3.6030 mL | |
| 40 mM | 0.1081 mL | 0.5404 mL | 1.0809 mL | 2.7022 mL | |
| 50 mM | 0.0865 mL | 0.4324 mL | 0.8647 mL | 2.1618 mL | |
| 60 mM | 0.0721 mL | 0.3603 mL | 0.7206 mL | 1.8015 mL | |
| 80 mM | 0.0540 mL | 0.2702 mL | 0.5404 mL | 1.3511 mL | |
| 100 mM | 0.0432 mL | 0.2162 mL | 0.4324 mL | 1.0809 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Butyrylcarnitine Related Classifications
HY-113168 Related Classifications
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