CD12681
CD12681 (compound 14) is a potent and selective RORγ inverse agonist with IC50 of 19 nM and 10 nM for RORγ GAL4 and CD4-IL-17 cells, respectively. CD12681 decreases the IL-17 inflammatory cell recruitment. CD12681 has the potential for the research of psoriasis.
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- CAS. Nr.: 1952239-59-6
- Formel: C25H33N3O4S
- Molecular Weight:471.61
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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RORγ |
CD12681 (compound 14) shows inhibition with IC50s of 44, >25, 9 µM for CYP 3A4, CYP 2D6, hERG, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1952239-59-6
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Molecular Weight 471.61
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Formel C25H33N3O4S
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SMILES
O=S(C1=CC(NC(N2CC3CCOCC3)=O)=C2C=C1)(N(C4=CC=C(C)C=C4C)CC(C)C)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CD12681 Related Classifications
HY-111366 Related Classifications
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