GABPB1 - GA binding protein transcription factor subunit beta 1 Gene
Also Known as E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; GABPB-1; E4TF1-47; E4TF1-53
Species: Homo sapiens
About GABPB1
This gene has 11 transcripts (splice variants), 152 orthologues and 2 paralogues. Ubiquitous expression in bone marrow (RPKM 6.9), lymph node (RPKM 6.8) and 25 other tissues.
Summary
This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
GABPB1 Products (7)
| mRNA | Protein | Name |
|---|---|---|
| NM_001320910.2 | NP_001307839.1 | GA-binding protein subunit beta-1 isoform beta 1 |
| NM_001320915.2 | NP_001307844.1 | GA-binding protein subunit beta-1 isoform 5 |
| NM_002041.5 | NP_002032.2 | GA-binding protein subunit beta-1 isoform gamma 1 |
| NM_005254.6 | NP_005245.2 | GA-binding protein subunit beta-1 isoform beta 1 |
| NM_016654.5 | NP_057738.1 | GA-binding protein subunit beta-1 isoform beta 2 |
| NM_016655.5 | NP_057739.1 | GA-binding protein subunit beta-1 isoform gamma 2 |
| NM_181427.4 | NP_852092.1 | GA-binding protein subunit beta-1 isoform gamma 2 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
GA-binding protein subunit beta-1 |
|
GABPB1 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Verweise |
|---|---|---|---|---|---|---|---|
|
Intra
|
GABPB1 | Q06547 | SNRPB2 | Homo sapiens | P08579 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | POGZ | Homo sapiens | Q7Z3K3 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | POGZ | Homo sapiens | Q7Z3K3 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | IL16 | Homo sapiens | Q14005-2 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | IL16 | Homo sapiens | Q14005-2 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | IL16 | Homo sapiens | Q14005-2 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | LMO4 | Homo sapiens | P61968 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | TRAF2 | Homo sapiens | Q12933 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | TRAF2 | Homo sapiens | Q12933 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | TRAF2 | Homo sapiens | Q12933 | 21516116 | |
|
Intra
|
GABPB1 | Q06547 | TRAF2 | Homo sapiens | Q12933 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | TRAF2 | Homo sapiens | Q12933 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | MED20 | Homo sapiens | Q9H944 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | MED20 | Homo sapiens | Q9H944 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | MED20 | Homo sapiens | Q9H944 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | HCFC1 | Homo sapiens | P51610 | 10675337 | |
|
Intra
|
GABPB1 | Q06547 | SNRPA | Homo sapiens | P09012 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | SNRPA | Homo sapiens | P09012 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | TDRD7 | Homo sapiens | Q8NHU6 | 33961781 | |
|
Intra
|
GABPB1 | Q06547 | TDRD7 | Homo sapiens | Q8NHU6 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | TDRD7 | Homo sapiens | Q8NHU6 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | TDRD7 | Homo sapiens | Q8NHU6 | 16189514 | |
|
Intra
|
GABPB1 | Q06547 | SNW1 | Homo sapiens | Q13573 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | SNW1 | Homo sapiens | Q13573 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | SNW1 | Homo sapiens | Q13573 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | GABPA | Homo sapiens | Q06546 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | GABPA | Homo sapiens | Q06546 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | GABPA | Homo sapiens | Q06546 | 33961781 | |
|
Intra
|
GABPB1 | Q06547 | FAM90A1 | Homo sapiens | Q86YD7 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | AGR2 | Homo sapiens | O95994 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | AGR2 | Homo sapiens | O95994 | 32296183 | |
|
Intra
|
GABPB1 | Q06547 | RBM11 | Homo sapiens | P57052 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | RBM11 | Homo sapiens | P57052 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | RBM11 | Homo sapiens | P57052 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | MAGEB18 | Homo sapiens | Q96M61 | 19060904 | |
|
Intra
|
GABPB1 | Q06547 | MAGEB18 | Homo sapiens | Q96M61 | 16189514 | |
|
Intra
|
GABPB1 | Q06547 | MAGEB18 | Homo sapiens | Q96M61 | 19060904 | |
|
Intra
|
GABPB1 | Q06547 | RSPH14 | Homo sapiens | Q9UHP6 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | RSPH14 | Homo sapiens | Q9UHP6 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | RSPH14 | Homo sapiens | Q9UHP6 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | LMO1 | Homo sapiens | P25800 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | LMO1 | Homo sapiens | P25800 | 25416956 | |
|
Intra
|
GABPB1 | Q06547 | LMO1 | Homo sapiens | P25800 | 25416956 |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | GABPB1 | RGD | RGD:1560391 |
| Bos taurus | GABPB1 | VGNC | VGNC:106750 |
| Felis catus | GABPB1 | VGNC | VGNC:80968 |
| Canis familiaris | GABPB1 | VGNC | VGNC:41051 |
| Mus musculus | GABPB1 | MGD | MGI:95611 |
| Macaca mulatta | GABPB1 | VGNC | VGNC:72845 |
| Others | GABPB1 | NCBI |