Psma1 - proteasome subunit alpha 1 Gene

Also Known as C2; HC2; Pros-30; alpha-type

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26440

Summary

Enables lipopolysaccharide binding activity. Involved in negative regulation of inflammatory response to antigenic stimulus. Part of Proteasome core complex. Is expressed in several structures, including alimentary system; brain ventricular layer; cranial ganglion; musculoskeletal system; and sensory organ. Orthologous to human PSMA1 (Proteasome 20S subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Psma1 Products (1)

mRNA Protein Name
NM_011965.2 NP_036095.1 proteasome subunit alpha type-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables lipopolysaccharide binding IDA
IDA: Inferred from direct assay
12874245 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16973439 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in negative regulation of inflammatory response to antigenic stimulus IMP
IMP: Inferred from mutant phenotype
12874245 MGI
Cellular Component GO Annotation Evidence Verweise Source
part of proteasome complex IDA
IDA: Inferred from direct assay
16973439 MGI
part of proteasome core complex IDA
IDA: Inferred from direct assay
16857966 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proteasome subunit alpha type-1

  • 20S proteasome subunit C2

  • macropain subunit C2

  • multicatalytic endopeptidase complex subunit C2

  • proteasome (prosome, macropain) subunit, alpha type 1

  • proteasome component C2

  • proteasome nu chain

Psma1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
Psma1 Q9R1P4 Zfand2b Mus musculus Q91X58
Anti Bait CoIP
18467495
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname Wirkung
Reinheit Phase
HY-P10740 CBP-1018 Ligand 99.21% Phase 1
Bioactive MoleculesInhibitory Antibodies (1)
Art. -Nr. Produktname Wirkung
Reinheit Phase
HY-P991708 Olsutamig Inhibitor 99.00% Phase 2

Pre-clinical Phase

Bioactive Molecules (9)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-43869 Vipivotide tetraxetan Ligand-Linker Conjugate 99.89% Unkown
HY-162965 Immunoproteasome activator 1 Activator 99.67% Unkown
HY-P10055 PSMA targeting peptide / Unkown
HY-P10055A PSMA targeting peptide TFA 99.09% Unkown
HY-185167 PSMA-1-DOTA / Unkown
HY-P11310 PSMA-1-SMCC Ligand 98.16% Unkown
HY-P11485 JR11-PEG3-HBED-CC-PSMA-03 / Unkown
HY-P11488 JR11-PEG3-DOTA-PSMA-03 Ligand / Unkown
HY-RS11291 PSMA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (2)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-P991359 Anti-FOLH1/PSMA Antibody (J591) Inhibitor 95.05% Unkown
HY-P991650 MDX1201 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Psma1 NCBI NCBI:5682