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Art. -Nr.: HY-125727

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Globosuxanthone A

Globosuxanthone A is a dihydroxanthenone with obvious antifungal activity towards Fusarium graminearum, Fusarium solani, and Botrytis cinerea with MIC values of 4, 8, and 16 μg/mL, respectively. Anticancer activity.

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CAS. Nr.: 917091-74-8
Formel: C₁₅H₁₂O₇
Molecular Weight:304.25

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Globosuxanthone A Chemical Structure

CAS. Nr.: 917091-74-8

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Bioz

Biologische Aktivität

Beschreibung

In Vitro

Globosuxanthone A shows cytotoxicities against NCI-H460, MCF-7, SF-268, PC-3, PC-3M, LNCaP, DU-145 cells (IC₅₀=0.65-3.6 µM)^[1].
Globosuxanthone A impairs cell cycle progression of NCI-H460 and PC-3M cells leading to accumulation in the G2/M and S phases ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 917091-74-8
Molecular Weight 304.25
Formel C₁₅H₁₂O₇
SMILES

O=C([C@@]1(O)C(C2=O)=C(OC3=C2C(O)=CC=C3)C=C[C@H]1O)OC
Structure Classification
- Phenols
- Monophenols
- Phenols
- Xanthones
Initial Source
- Endogenous metabolite
- Human Gut Microbiota Metabolites
- Microorganisms
Microdiplodia sp
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Miao C, et al. Antifungal xanthones produced by the endophytic fungus Paraconionthyrium sp. YM 311593. Folia Microbiol (Praha). 2020;65(3):567-572. [Content Brief]

[2]. Wijeratne EM, et al. A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity. Bioorg Med Chem. 2006;14(23):7917-7923. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Globosuxanthone A

Alisertib

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K858 (Racemic)

Glyceryl 1-monooctanoate

Lydicamycin

A-26771B

Saccharocarcin A

Reveromycin D

β-Defensin-4 (human)

Fumiquinazoline D

Alisertib (Standard)

AKI603

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

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Globosuxanthone A

Alisertib

Sphinganine-C17

K858 (Racemic)

Glyceryl 1-monooctanoate

Lydicamycin

A-26771B

Saccharocarcin A

Reveromycin D

β-Defensin-4 (human)

Fumiquinazoline D

Alisertib (Standard)

AKI603

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Globosuxanthone A Related Classifications

HY-125727 Related Classifications