country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-P992543

Copy Link Print Information

IBI3011

IBI3011 is a humanized anti-IL1RAP monoclonal antibody. IBI3011 inhibits inflammatory pathways driven by IL1, IL33, and IL36. IBI3011 can be used in research related to inflammatory and immune diseases, such as gout and arthritis.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

IBI3011 Chemical Structure

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- In Vivo
- Target
- Conjugated
- Anwendung
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Species Reactivity

Human

IC₅₀ & Target

^[1]

IL-1

IL33

IL36

Alle Interleukin Related Isoform-spezifische Produkte anzeigen :

In Vitro

Innate Immunity

IBI3011 exhibits high affinity for human and cynomolgus monkey IL1RAP proteins at both the protein and cellular levels, but shows no affinity for mouse IL1RAP protein^[1].
IBI3011 inhibits the secretion of inflammatory cytokines TNFα and IFNγ by peripheral blood mononuclear cells (PBMCs) stimulated with IL1α/β, IL33, and IL36α/β/γ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Target

IL-1RAP

Conjugated

Unconjugated

Anwendung

ELISA, FACS, Functional assay

Chemical Information

SMILES

[IBI3011]
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Inhibitory Antibodies User Guide (603 KB)

Verweise

[1]. Tian H, et al. IBI3011, a Humanized anti-IL1RAP Monoclonal Antibody, Inhibits IL1, IL33, IL36-driven Inflammation Pathway, and Attenuates Inflammation in Preclinical Inflammatory Disease Model [abstract]. Arthritis Rheumatol. 2025; 77 (suppl 9).

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen