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Art. -Nr.: HY-N9376

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Kansuinine E

Kansuinine E is a plant-derived nitric oxide inhibitor (IC₅₀=6.3 μM). Kansuinine E belongs to jatrophane-type diterpenoids and is isolated from the roots of E. kansui.

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CAS. Nr.: 672945-84-5
Formel: C₄₁H₄₇NO₁₄
Molecular Weight:777.81

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (278 KB)

Kansuinine E Chemical Structure

CAS. Nr.: 672945-84-5

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Kansuinine E is a plant-derived nitric oxide inhibitor (IC₅₀=6.3 μM). Kansuinine E belongs to jatrophane-type diterpenoids and is isolated from the roots of E. kansui^[1].

IC₅₀ & Target

IC50: 6.3 μM (nitric oxide)^[1].

Alle NO Synthase Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
NIH3T3	ED₅₀	>50 μg/mL Compound: 5, kansuinin E	Survival effect on NGF-dependent mouse NIH/3T3 cells expressing TrkB assessed as cell viability after 2 days by MTT assay Survival effect on NGF-dependent mouse NIH/3T3 cells expressing TrkB assessed as cell viability after 2 days by MTT assay	[PMID: 15387657]
NIH3T3	ED₅₀	0.23 μg/mL Compound: 5, kansuinin E	Survival effect on NGF-dependent mouse NIH/3T3 cells expressing TrkA assessed as cell viability after 2 days by MTT assay Survival effect on NGF-dependent mouse NIH/3T3 cells expressing TrkA assessed as cell viability after 2 days by MTT assay	[PMID: 15387657]

Chemical Information

CAS. Nr. 672945-84-5
Molecular Weight 777.81
Formel C₄₁H₄₇NO₁₄
SMILES

C[C@H]1C[C@@]2(OC(C)=O)[C@@H]([C@@H](OC(C)=O)C([C@H](OC(C)=O)[C@@H](OC(C3=CC=CC=C3)=O)[C@@H](OC(C4=CN=CC=C4)=O)C(C)(C)[C@@H]5[C@H]([C@@H](C)C2=O)O5)=C)[C@H]1OC(C)=O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (278 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Lee JW, et al. Jatrophane and ingenane-type diterpenoids from Euphorbia kansui inhibit the LPS-induced NO production in RAW 264.7 cells. Bioorg Med Chem Lett. 2016;26(14):3351-3354. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
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Kansuinine E

Alle NO Synthase Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Kansuinine E Related Classifications

HY-N9376 Related Classifications