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Art. -Nr.: HY-117031

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m-PEG8-MS

Name: m-PEG8-MS
Brand: MedChemExpress
SKU: HY-117031
Price: 76.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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m-PEG8-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

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Reinheit : 99.98%
CAS. Nr.: 1059588-19-0
Formel: C₁₈H₃₈O₁₁S
Molecular Weight:462.55

Speicherung:

Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

m-PEG8-MS Chemical Structure

CAS. Nr.: 1059588-19-0

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
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Calculators
Help & FAQs
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Biologische Aktivität

Beschreibung

m-PEG8-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

^[1]

Cleavable Linker

PEGs

Alle ADC Linkers Isoform-spezifische Produkte anzeigen :

Alle PROTAC Linkers Isoform-spezifische Produkte anzeigen :

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 1059588-19-0
Appearance Liquid
Molecular Weight 462.55
Formel C₁₈H₃₈O₁₁S
Color Colorless to light yellow
SMILES

CS(OCCOCCOCCOCCOCCOCCOCCOCCOC)(=O)=O
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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- In Vitro
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m-PEG8-MS

Alle ADC Linkers Isoform-spezifische Produkte anzeigen

Alle PROTAC Linkers Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Beschreibung

IC50 & Target

In Vitro

Chemical Information

Reinheit & Dokumentation

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Calculators

Help & FAQs

m-PEG8-MS Related Classifications

HY-117031 Related Classifications

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