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Nebratamig

(Synonyms: GNC-035)
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Based on 1 Customer Validation

Nebratamig (GNC-035) is an anti-ROR1/anti-CD3/anti-PD-L1/anti-4-1BB tetra-specific antibody with potential immunostimulatory and antineoplastic activities.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 97.34%
  • CAS. Nr.: 2694723-68-5
  • Molecular Weight:302.32 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Nebratamig
  • Experimental Validation Results for Nebratamig
  • Experimental Validation Results for Nebratamig
  • Experimental Validation Results for Nebratamig
  • Experimental Validation Results for Nebratamig
  • Experimental Validation Results for Nebratamig
  • Nebratamig Chemical Structure
    Nebratamig Chemical Structure
CAS. Nr.: 2694723-68-5
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    scFv-G1K-scFv-scFv_kappa

  • 1/16

    Immobilized ROR1 Protein, Human (HEK293, His, HY-P70317) can bind Nebratamig. The EC50 for this effect is 8.808 ng/mL.

  • 1/16

    Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Nebratamig. The EC50 for this effect is 25.92 ng/mL.

  • 1/16

    Immobilized 4-1BB/TNFRSF9 Protein, Human (HEK293, His, HY-P70678) can bind Nebratamig. The EC50 for this effect is 8.016 ng/mL.

  • 1/16

    Immobilized PD-L1 Protein, Human (HEK293, HY-P73361) can bind Nebratamig. The EC50 for this effect is 14.78 ng/mL.

  • 1/16

    Flow cytometric analysis of 1×106 Jurkat cells labelling CD3 (red) with Nebratamig (HY-P991209). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Nebratamig Chemical Structure
    1/16
  • Nebratamig
  • Immobilized ROR1 Protein, Human (HEK293, His, HY-P70317) can bind Nebratamig. The EC50 for this effect is 8.808 ng/mL.
  • Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Nebratamig. The EC50 for this effect is 25.92 ng/mL.
  • Immobilized 4-1BB/TNFRSF9 Protein, Human (HEK293, His, HY-P70678) can bind Nebratamig. The EC50 for this effect is 8.016 ng/mL.
  • Immobilized PD-L1 Protein, Human (HEK293, HY-P73361) can bind Nebratamig. The EC50 for this effect is 14.78 ng/mL.
  • Flow cytometric analysis of 1×106 Jurkat cells labelling CD3 (red) with Nebratamig (HY-P991209). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • scFv-G1K-scFv-scFv_kappa