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Art. -Nr.: HY-W676876

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Oxynitidine

Oxynitidine is an HBV inhibitor (ID₅₀=30.8 µg/mL), which can effectively inhibit the DNA replication activity of HBV. Oxynitidine can be used in the study of viral infections.

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CAS. Nr.: 548-31-2
Formel: C₂₁H₁₇NO₅
Molecular Weight:363.36

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Oxynitidine Chemical Structure

CAS. Nr.: 548-31-2

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Oxynitidine is an HBV inhibitor (ID₅₀=30.8 µg/mL), which can effectively inhibit the DNA replication activity of HBV. Oxynitidine can be used in the study of viral infections^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	GI₅₀	39 μM Compound: 1	Growth inhibition of human A549 cells incubated for 72 hrs by MTT assay Growth inhibition of human A549 cells incubated for 72 hrs by MTT assay	[PMID: 31176097]
A549	GI₅₀	39.38 μM Compound: 6	Growth inhibition of human A549 cells after 72 hrs by MTT assay Growth inhibition of human A549 cells after 72 hrs by MTT assay	[PMID: 30336023]
CCRF-CEM	GI₅₀	26.52 μM Compound: 6	Growth inhibition of human CCRF-CEM cells after 72 hrs by MTT assay Growth inhibition of human CCRF-CEM cells after 72 hrs by MTT assay	[PMID: 30336023]
DU-145	GI₅₀	64 μM Compound: 1	Growth inhibition of human DU145 cells incubated for 72 hrs by MTT assay Growth inhibition of human DU145 cells incubated for 72 hrs by MTT assay	[PMID: 31176097]
DU-145	GI₅₀	64.23 μM Compound: 6	Growth inhibition of human DU145 cells after 72 hrs by MTT assay Growth inhibition of human DU145 cells after 72 hrs by MTT assay	[PMID: 30336023]
HCT-116	GI₅₀	74 μM Compound: 1	Growth inhibition of human HCT116 cells incubated for 72 hrs by MTT assay Growth inhibition of human HCT116 cells incubated for 72 hrs by MTT assay	[PMID: 31176097]
HCT-116	GI₅₀	74.79 μM Compound: 6	Growth inhibition of human HCT116 cells after 72 hrs by MTT assay Growth inhibition of human HCT116 cells after 72 hrs by MTT assay	[PMID: 30336023]
Huh-7	GI₅₀	>100 μM Compound: 6	Growth inhibition of human HuH7 cells after 72 hrs by MTT assay Growth inhibition of human HuH7 cells after 72 hrs by MTT assay	[PMID: 30336023]
MCF7	GI₅₀	31 μM Compound: 1	Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay	[PMID: 31176097]

Chemical Information

CAS. Nr. 548-31-2
Molecular Weight 363.36
Formel C₂₁H₁₇NO₅
SMILES

O=C1C2=CC(OC)=C(C=C2C3=C(N1C)C4=CC5=C(OCO5)C=C4C=C3)OC
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Chin-Teng Chang, et al. Coumarins and anti-HBV constituents from Zanthoxylum schinifolium.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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