Polyestradiol phosphate
Based on 136 publication(s) in Google Scholar
Polyestradiol phosphate (Polyestrol phosphate) is a polymer of Estradiol (HY-B0141) and Phosphoric acid. Polyestradiol phosphate can be used in the research of prostate cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 28014-46-2
- Formel: (C18H24O2·H3PO4)x
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Polyestradiol phosphate
More- Cell Metab. 2024 Nov 5;36(11):2402-2418.e10. [Abstract]
- Bioact Mater. 2025 Jul 15:53:240-252. [Abstract]
- Cancer Res. 2025 Nov 19. [Abstract]
- Nat Commun. 2025 Aug 22;16(1):7854. [Abstract]
- Bone Res. 2026 Mar 17;14(1):31. [Abstract]
- Nat Chem Biol. 2022 Nov;18(11):1196-1203. [Abstract]
- Neuro Oncol. 2024 Jan 5;26(1):137-152. [Abstract]
- Theranostics. 2020 Aug 29;10(24):10874-10891. [Abstract]
- J Adv Res. 2024 Dec 9:S2090-1232(24)00565-4. [Abstract]
- Engineering. 2025 Aug 27.
- Gut Microbes. 2026 Dec 31;18(1):2657047. [Abstract]
- Biosens Bioelectron. 2026 Sep 1:307:118716. [Abstract]
- Biosens Bioelectron. 2022 Nov 1:215:114548. [Abstract]
- Pharmacol Res. 2022 Mar:177:106050. [Abstract]
- ACS Cent Sci. 2026 Mar 25;12(4):497-523. [Abstract]
- Cell Death Dis. 2020 Oct 6;11(10):831. [Abstract]
- Genome Biol. 2025 May 9;26(1):124. [Abstract]
- Proc Natl Acad Sci U S A. 2025 Aug 19;122(33):e2507571122. [Abstract]
- J Cachexia Sarcopenia Muscle. 2025 Apr;16(2):e13807. [Abstract]
- Proc Natl Acad Sci U S A. 2025 Mar 25;122(12):e2426107122. [Abstract]
- J Cachexia Sarcopenia Muscle. 2025 Feb;16(1):e13693. [Abstract]
- Cell Commun Signal. 2019 Aug 14;17(1):94. [Abstract]
- Int J Biol Macromol. 2026 Mar:352:151224. [Abstract]
- Int J Biol Macromol. 2023 May 1:236:123987. [Abstract]
- Phytomedicine. 2026 Jun 11:159:158427. [Abstract]
- Phytomedicine. 2025 Jun:141:156701. [Abstract]
- Phytomedicine. 2025 Mar:138:156429. [Abstract]
- Phytomedicine. 2024 Jul 25:130:155767. [Abstract]
- Phytomedicine. 2023 Jan:109:154593. [Abstract]
- Free Radic Biol Med. 2023 Feb 1:195:231-244. [Abstract]
- Chemosphere. 2024 Oct:366:143466. [Abstract]
- Sci Total Environ. 2024 Jul 6:947:174543. [Abstract]
- Sci Total Environ. 2024 May 25:173419. [Abstract]
- NPJ Breast Cancer. 2022 Mar 10;8(1):31. [Abstract]
- J Transl Med. 2025 Oct 17;23(1):1128. [Abstract]
- Biomed Pharmacother. 2024 Jun 3:176:116852. [Abstract]
- J Transl Med. 2024 Mar 9;22(1):255. [Abstract]
- Biomed Pharmacother. 2019 Aug:116:109001. [Abstract]
- Environ Pollut. 2022 Jan 1;292(Pt B):118370. [Abstract]
- Environ Pollut. 2021 Feb 1;270:116015. [Abstract]
- Aging Cell. 2026 Apr;25(4):e70463. [Abstract]
- Aging Cell. 2024 Aug 7:e14303. [Abstract]
- J Med Chem. 2026 Jun 11;69(11):13618-13634. [Abstract]
- J Med Chem. 2025 Oct 15. [Abstract]
- J Med Chem. 2025 Jun 12;68(11):11127-11148. [Abstract]
- J Med Chem. 2025 Mar 27;68(6):6127-6148. [Abstract]
- Br J Cancer. 2022 Sep;127(5):927-936. [Abstract]
- J Med Chem. 2022 Mar 10;65(5):3894-3912. [Abstract]
- Anal Chem. 2026 Jun 16;98(23):16962-16970. [Abstract]
- NPJ Regen Med. 2023 May 2;8(1):23. [Abstract]
- J Anim Sci Biotechnol. 2023 Jan 5;14(1):6. [Abstract]
- Mol Med. 2025 Feb 25;31(1):78. [Abstract]
- Phytother Res. 2025 May 8. [Abstract]
- Cell Mol Life Sci. 2024 Dec 27;82(1):17. [Abstract]
- Hum Reprod. 2025 Jul 29:deaf130. [Abstract]
- JCI Insight. 2024 Oct 31:e182418. [Abstract]
- Ecotoxicol Environ Saf. 2024 Jul 2:281:116680. [Abstract]
- Hum Reprod. 2019 May 1;34(5):804-812. [Abstract]
- Biochem Pharmacol. 2026 Jun 12;251(Pt 2):118163. [Abstract]
- Biochem Pharmacol. 2026 May:247:117796. [Abstract]
- Biochem Pharmacol. 2025 Oct 29;243(Pt 1):117481. [Abstract]
- Biochem Pharmacol. 2024 Dec;230(Pt 1):116564. [Abstract]
- Genome Res. 2024 May 15;34(4):539-555. [Abstract]
- Pain. 2021 Jun 1;162(6):1882-1896. [Abstract]
- Chem Biol Interact. 2026 Jul 25:435:112138. [Abstract]
- J Ethnopharmacol. 2025 May 10:119968. [Abstract]
- J Ethnopharmacol. 2021 Jun 28:274:114064. [Abstract]
- Mol Ther Oncolytics. 2022 Aug 5:26:372-386. [Abstract]
- Cells. 2026 Jan 29;15(3):260. [Abstract]
- J Clin Endocrinol Metab. 2021 Apr 23;106(5):1410-1426. [Abstract]
- Inflammation. 2025 Aug 2. [Abstract]
- Int J Mol Sci. 2026 May 14;27(10):4354. [Abstract]
- Biomed Signal Process Control. 2026 Feb 26.
- Int J Mol Sci. 2023 Apr 6;24(7):6826. [Abstract]
- Bioorg Chem. 2026 Jul 15:176:109843. [Abstract]
- Int Immunopharmacol. 2025 Aug 19:164:115392. [Abstract]
- Int Immunopharmacol. 2025 Jan 24:148:114104. [Abstract]
- Int Immunopharmacol. 2024 Nov 2;143(Pt 3):113527. [Abstract]
- Int Immunopharmacol. 2024 Sep 5;142(Pt A):113059. [Abstract]
- Eur J Pharmacol. 2022 May 15;923:174908. [Abstract]
- Int Immunopharmacol. 2020 Jan;78:105937. [Abstract]
- Neuropharmacology. 2024 Sep 5:110138. [Abstract]
- Molecules. 2022 Aug 6;27(15):5000. [Abstract]
- Cell Rep Methods. 2023 Oct 23;3(10):100599. [Abstract]
- Cancers (Basel). 2024 Feb 9;16(4):726. [Abstract]
- Aquat Toxicol. 2026 Jun 2:298:107880. [Abstract]
- Poult Sci. 2026 May 25.
- Poult Sci. 2025 May 3;104(7):105259. [Abstract]
- Biochim Biophys Acta Mol Basis Dis. 2024 Mar;1870(3):167011. [Abstract]
- J Cell Mol Med. 2020 Jan;24(2):1599-1613. [Abstract]
- Sci Rep. 2026 Apr 20;16(1):12890. [Abstract]
- Sci Rep. 2025 May 8;15(1):16053. [Abstract]
- Sci Rep. 2025 Mar 12;15(1):8531. [Abstract]
- Cell Signal. 2025 Sep 8:136:112121. [Abstract]
- Cell Signal. 2024 Aug 13:111346. [Abstract]
- Aquacult Rep. February 2022, 100930.
- Neurobiol Stress. 2020 Oct 14;13:100256. [Abstract]
- Mol Hum Reprod. 2025 Jul 3;31(3):gaaf037. [Abstract]
- Mol Med Rep. 2024 Jul;30(1):123. [Abstract]
- Food Chem Toxicol. 2023 Jun:176:113807. [Abstract]
- BMC Cancer. 2026 May 4;26(1):768. [Abstract]
- Life Metab. 2023 Nov 6;3(1):load041. [Abstract]
- BMC Cancer. 2023 Oct 31;23(1):1047. [Abstract]
- Naunyn Schmiedebergs Arch Pharmacol. 2025 Dec 18. [Abstract]
- Mol Reprod Dev. 2025 May;92(5):e70025. [Abstract]
- Genomics. 2025 Jan 21;117(2):111002. [Abstract]
- Breast Cancer Res Treat. 2023 Dec;202(3):595-606. [Abstract]
- Biol Reprod. 2022 Oct 11;107(4):1026-1034. [Abstract]
- J Pharmacol Sci. 2024 May;155(1):1-13. [Abstract]
- Mar Biotechnol (NY). 2026 Apr 20;28(3):66. [Abstract]
- Genes (Basel). 2023 Jul 19;14(7):1466. [Abstract]
- Front Genet. 2022 Sep 20:13:992444. [Abstract]
- J Assist Reprod Genet. 2024 Nov;41(11):3189-3200. [Abstract]
- PLoS One. 2020 Oct 1;15(10):e0239659. [Abstract]
- J Steroid Biochem Mol Biol. 2025 Jun 2:106800. [Abstract]
- Fishes. 2023 Dec 19, 9(1), 1.
- Gene. 2023 Aug 30:879:147592. [Abstract]
- Fishes. 2022, 7(5), 223.
- Steroids. 2022 Dec:188:109114. [Abstract]
- Biochem Biophys Res Commun. 2025 Jun 14:776:152212. [Abstract]
- Biochem Biophys Res Commun. 2025 May 20:772:152050. [Abstract]
- Physiol Rep. 2024 Sep;12(17):e70047. [Abstract]
- Zygote. 2022 Jun;30(3):330-337. [Abstract]
- Patent. US20250320507A1.
- bioRxiv. 2025 Sep 12.
- SSRN. 2025 Jan 27.
- bioRxiv. 2024 August 04.
- SSRN. 2023 Nov 29.
- Research Square Preprint. 2023 Dec 2.
- bioRxiv. 2023 Nov 2:2023.10.30.564691. [Abstract]
- bioRxiv. 2023 Jul 27.
- Research Square Preprint. 2023 May 8.
- Harvard University. 2023 Mar. 30487357.
- Research Square Preprint. 2022 Jun.
- Research Square Preprint. 2022 Feb.
- Res Sq. 2020 Dec 31:rs.3.rs-100914. [Abstract]
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Biologische Aktivität
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Human Endogenous Metabolite |
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 28014-46-2
-
Formel (C18H24O2·H3PO4)x
-
SMILES
C[C@@]1([C@H]2O)[C@](CC2)([H])[C@@](CCC3=C4C=CC(O)=C3)([H])[C@]4([H])CC1.O=P(O)(O)O.[x]
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Synonyms
Polyestrol phosphate
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (136)
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Journal Impact Factor
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Most Recent
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Cell Metab
Sensing steroid hormone 17α-hydroxypregnenolone by GPR56 enables protection from ferroptosis-induced liver injury. [Abstract]2024 Nov 5;36(11):2402-2418.e10. PMID: 39389061 -
Bioact Mater
2025 Jul 15:53:240-252. PMID: 40697396 -
Cancer Res
Estrogen Production in Pancreatic Cancer Shapes a Tumor Suppressive Stromal Microenvironment. [Abstract]2025 Nov 19. PMID: 41258799 -
Nat Commun
Harnessing artificial intelligence to identify Bufalin as a molecular glue degrader of estrogen receptor alpha. [Abstract]2025 Aug 22;16(1):7854. PMID: 40846852 -
Bone Res
C/EBPβ dictates postmenopausal FSHβ transcription and blockade of AEP/C/EBPβ pathway alleviates osteoporosis. [Abstract]2026 Mar 17;14(1):31. PMID: 41844581 -
Nat Chem Biol
2022 Nov;18(11):1196-1203. PMID: 35982227 -
Neuro Oncol
A disintegrin and metalloproteinase 22 activates integrin β1 through its disintegrin domain to promote the progression of pituitary adenoma. [Abstract]2024 Jan 5;26(1):137-152. PMID: 37555799 -
Theranostics
Dysfunction of estrogen-related receptor alpha-dependent hepatic VLDL secretion contributes to sex disparity in NAFLD/NASH development. [Abstract]2020 Aug 29;10(24):10874-10891. PMID: 33042259
Polyestradiol phosphate purchased from MedChemExpress. Usage Cited in: Theranostics. 2020 Aug 29;10(24):10874-10891. [Abstract]
Estradiol (E2) (100 nM; 36 h) treatment can enhance the expression of ERRα and VLDL-related genes such as Apob, Mttp and Pla2g12b, whereas the induction is blocked with loss of ERRα in primary hepatocytes.
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J Adv Res
Dual regulation of phaseol on osteoclast formation and osteoblast differentiation by targeting TAK1 kinase for osteoporosis treatment. [Abstract]2024 Dec 9:S2090-1232(24)00565-4. PMID: 39662728 -
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Gut Microbes
Gut microbiota signatures in primary aldosteronism and functional identification of an aldosterone-degrading gut bacterium. [Abstract]2026 Dec 31;18(1):2657047. PMID: 41964107 -
Biosens Bioelectron
Highly sensitive detection for endocrine disruptors using human cell biosensors expressing red fluorescence protein mScarlet3. [Abstract]2026 Sep 1:307:118716. PMID: 42070441 -
Biosens Bioelectron
Split aptamer regulated CRISPR/Cas12a biosensor for 17β-estradiol through a gap-enhanced Raman tags based lateral flow strategy. [Abstract]2022 Nov 1:215:114548. PMID: 35870335 -
Pharmacol Res
Potential synthetic lethality for breast cancer: A selective sirtuin 2 inhibitor combined with a multiple kinase inhibitor sorafenib. [Abstract]2022 Mar:177:106050. PMID: 34973468 -
ACS Cent Sci
An Epigenetic Switch for Sex-Specific Brain Resilience in Stroke: Targeting HDAC2 to Amplify Endogenous Oxytocin Signaling. [Abstract]2026 Mar 25;12(4):497-523. PMID: 42038487 -
Cell Death Dis
2020 Oct 6;11(10):831. PMID: 33024087 -
Genome Biol
Endometrial tumorigenesis involves epigenetic plasticity demarcating non-coding somatic mutations and 3D-genome alterations. [Abstract]2025 May 9;26(1):124. PMID: 40346709 -
Proc Natl Acad Sci U S A
2025 Aug 19;122(33):e2507571122. PMID: 40815626 -
J Cachexia Sarcopenia Muscle
Oestrogen Receptor Alpha in Myocyte Maintains Muscle Regeneration in Duchenne Muscular Dystrophy. [Abstract]2025 Apr;16(2):e13807. PMID: 40258782 -
Proc Natl Acad Sci U S A
Androgen receptors in corticotropin-releasing hormone neurons mediate the sexual dimorphism in restraint-induced thymic atrophy. [Abstract]2025 Mar 25;122(12):e2426107122. PMID: 40106355 -
J Cachexia Sarcopenia Muscle
Nicotinamide Phosphoribosyltransferase Acetylation Mediating Muscle Dysfunction Contributes to Sleep Apnoea in Obesity. [Abstract]2025 Feb;16(1):e13693. PMID: 39901373
Polyestradiol phosphate purchased from MedChemExpress. Usage Cited in: J Cachexia Sarcopenia Muscle. 2025 Feb;16(1):e13693. [Abstract]
Estradiol (E2) (10-100 nM) exhibites an increase in the SIRT1 protein level in C2C12 cells, without significantly affecting the mRNA level.
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Cell Commun Signal
Increased HERV-E clone 4-1 expression contributes to DNA hypomethylation and IL-17 release from CD4+ T cells via miR-302d/MBD2 in systemic lupus erythematosus. [Abstract]2019 Aug 14;17(1):94. PMID: 31412880 -
Int J Biol Macromol
Reticuline isomerase AKR1B1 with aldo-keto reductase activity and detoxification function from the insect Blaps rhynchopetera. [Abstract]2026 Mar:352:151224. PMID: 41791543 -
Int J Biol Macromol
Estrogen-mediated oar-miR-485-5p targets PPP1R13B to regulate myoblast proliferation in sheep. [Abstract]2023 May 1:236:123987. PMID: 36906210
Polyestradiol phosphate purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2023 May 1:236:123987. [Abstract]
Estradiol (1-100 nM; 6-72 h) promotes the proliferation of sheep myoblasts.
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Phytomedicine
AI-driven discovery of synergistic combinations from Psoralea corylifolia fruit for treating osteoporosis. [Abstract]2026 Jun 11:159:158427. PMID: 42308991 -
Phytomedicine
Kaempferol targets Src to exert its chemopreventive effects on mammary tumorigenesis via regulation of the PI3K/AKT pathway. [Abstract]2025 Jun:141:156701. PMID: 40220416 -
Phytomedicine
Glycyrol alleviates osteoporosis through dual modulation on osteoclastogenesis and osteogenesis by targeting Syk signaling pathway. [Abstract]2025 Mar:138:156429. PMID: 39939034 -
Phytomedicine
Dihydrotanshinone I targets ESR1 to induce DNA double-strand breaks and proliferation inhibition in hepatocellular carcinoma. [Abstract]2024 Jul 25:130:155767. PMID: 38833789 -
Phytomedicine
Paeonol ameliorates endometrial hyperplasia in mice via inhibiting PI3K/AKT pathway-related ferroptosis. [Abstract]2023 Jan:109:154593. PMID: 36610113 -
Free Radic Biol Med
17β-estradiol plays the anti-osteoporosis role via a novel ESR1-Keap1-Nrf2 axis-mediated stress response activation and Tmem119 upregulation. [Abstract]2023 Feb 1:195:231-244. PMID: 36592659 -
Chemosphere
Early pregnancy exposure to Microcystin-LR compromises endometrial decidualization in mice via the PI3K/AKT/FOXO1 signaling pathway. [Abstract]2024 Oct:366:143466. PMID: 39369752 -
Sci Total Environ
Insights into the role of FoxL2 in tebuconazole-induced male- biased sex differentiation of zebrafish. [Abstract]2024 Jul 6:947:174543. PMID: 38977095
Polyestradiol phosphate purchased from MedChemExpress. Usage Cited in: Sci Total Environ. 2024 Jul 6:947:174543. [Abstract]
Estradiol (E2) (1 μM, 8 h) alone or in combination with TEB (100 μM, 8 h) (TEB + E2) significantly increases the protein expression levels of FoxL2 and pFoxL2 (Ser238) in ZF4 cells.
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Sci Total Environ
Integrated toxicity of secondary, tertiary, wetland effluents on human stem cells triggered by ERα and PPARγ agonists. [Abstract]2024 May 25:173419. PMID: 38802024 -
NPJ Breast Cancer
Estrogen receptor inhibition mediates radiosensitization of ER-positive breast cancer models. [Abstract]2022 Mar 10;8(1):31. PMID: 35273179 -
J Transl Med
Pleiotrophin modulates cell proliferation, prostate smooth muscle contraction and fibrosis in hyperplastic prostate. [Abstract]2025 Oct 17;23(1):1128. PMID: 41107820 -
Biomed Pharmacother
Chemopreventive effects of atractylenolide-III on mammary tumorigenesis via activation of the Nrf2/ARE pathway through autophagic degradation of Keap1. [Abstract]2024 Jun 3:176:116852. PMID: 38834007 -
J Transl Med
Identification and functional activity of Nik related kinase (NRK) in benign hyperplastic prostate. [Abstract]2024 Mar 9;22(1):255. PMID: 38459501 -
Biomed Pharmacother
Coupling the near-infrared fluorescent dye IR-780 with cabazitaxel makes renal cell carcinoma chemotherapy possible. [Abstract]2019 Aug:116:109001. PMID: 31146114 -
Environ Pollut
Benzophenone-1 induced aberrant proliferation and metastasis of ovarian cancer cells via activated ERα and Wnt/β-catenin signaling pathways. [Abstract]2022 Jan 1;292(Pt B):118370. PMID: 34656677 -
Environ Pollut
Screening of potential oestrogen receptor α agonists in pesticides via in silico, in vitro and in vivo methods. [Abstract]2021 Feb 1;270:116015. PMID: 33352482
Polyestradiol phosphate purchased from MedChemExpress. Usage Cited in: Environ Pollut. 2021 Feb 1;270:116015. [Abstract]
Estradiol (1-10 nM; 24 h) significantly induces mRNA expression of both pS2 and NRF1 genes in MCF-7 cells.
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Aging Cell
Senescence-Driven Remodeling Defines an Aggressive and Immunomodulatory Subtype of Endometriosis. [Abstract]2026 Apr;25(4):e70463. PMID: 41891132 -
Aging Cell
2024 Aug 7:e14303. PMID: 39113346
Polyestradiol phosphate purchased from MedChemExpress. Usage Cited in: Aging Cell. 2024 Aug 7:e14303. [Abstract]
Estradiol (3-25 ng/mouse; s.c.; for 7 consecutive days) significantly decreases LAMIN A levels while increasing PROGERIN and PRELAMIN A levels in the uteri of mice injected with 10 ng or 25 ng, compared to those receiving the 3 ng dose.
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J Med Chem
Development of Novel Estradiol-Indole Hybrids Targeting SERT and ERβ as Potential Antidepressants. [Abstract]2026 Jun 11;69(11):13618-13634. PMID: 42154662 -
J Med Chem
Discovery of the First-In-Class HSD17B13/PPAR Multitarget Modulators for the Treatment of Metabolic Dysfunction-Associated Steatohepatitis. [Abstract]2025 Oct 15. PMID: 41088966 -
J Med Chem
Discovery of Highly Potent, Selective, and Liver-Targeting HSD17B13 Inhibitor with Robust In Vivo Anti-MASH Activity. [Abstract]2025 Jun 12;68(11):11127-11148. PMID: 40387207 -
J Med Chem
Discovery of First-in-Class FXR and HSD17B13 Dual Modulator for the Treatment of Metabolic Dysfunction-Associated Fatty Liver Disease. [Abstract]2025 Mar 27;68(6):6127-6148. PMID: 39851255 -
Br J Cancer
Androgen and oestrogen receptor co-expression determines the efficacy of hormone receptor-mediated radiosensitisation in breast cancer. [Abstract]2022 Sep;127(5):927-936. PMID: 35618789 -
J Med Chem
Activators of the Anticipatory Unfolded Protein Response with Enhanced Selectivity for Estrogen Receptor Positive Breast Cancer. [Abstract]2022 Mar 10;65(5):3894-3912. PMID: 35080871 -
Anal Chem
High-Throughput Reactive Desorption Electrospray Ionization Mass Spectrometry for Targeted Derivatization and Analysis of Poorly Ionized Small Molecules. [Abstract]2026 Jun 16;98(23):16962-16970. PMID: 42223360 -
NPJ Regen Med
Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis. [Abstract]2023 May 2;8(1):23. PMID: 37130846 -
J Anim Sci Biotechnol
Cysteine dioxygenase and taurine are essential for embryo implantation by involving in E2-ERα and P4-PR signaling in mouse. [Abstract]2023 Jan 5;14(1):6. PMID: 36604722 -
Mol Med
A novel mechanism of FTO modulating the progression of endometriosis through mediating the m6A methylation of GEF-H1 in a YTHDF1-dependent manner. [Abstract]2025 Feb 25;31(1):78. PMID: 40000966 -
Phytother Res
Identification of Sinigrin as Active Compound of Rape Pollen for Treating Benign Prostatic Hyperplasia Through PI3K/AKT/mTOR Axis. [Abstract]2025 May 8. PMID: 40343383 -
Cell Mol Life Sci
Upregulated YTHDC1 mediates trophoblastic dysfunction inducing preterm birth in ART conceptions through enhanced RPL37 translation. [Abstract]2024 Dec 27;82(1):17. PMID: 39725796 -
Hum Reprod
Harmine inhibits oxidative phosphorylation, thus regulating the polarization of macrophages mediated by extracellular adenosine in endometriosis. [Abstract]2025 Jul 29:deaf130. PMID: 40730246 -
JCI Insight
Dynamic transcriptome analysis of osteal macrophages identifies a distinct subset with senescence features in experimental osteoporosis. [Abstract]2024 Oct 31:e182418. PMID: 39480497 -
Ecotoxicol Environ Saf
Impaired GPX4 activity elicits ferroptosis in alveolar type II cells promoting PHMG-induced pulmonary fibrosis development. [Abstract]2024 Jul 2:281:116680. PMID: 38964057 -
Hum Reprod
2019 May 1;34(5):804-812. PMID: 30989213 -
Biochem Pharmacol
Targeting neuropilin-1 attenuates 4-hydroxytamoxifen-induced stemness and sensitizes ERα-re-expressing TNBC to tamoxifen. [Abstract]2026 Jun 12;251(Pt 2):118163. PMID: 42285368 -
Biochem Pharmacol
Mutant NPM1-regulated estrogen signaling promotes leukemia cell survival by upregulating HGF and represents a therapeutic vulnerability. [Abstract]2026 May:247:117796. PMID: 41679667 -
Biochem Pharmacol
Estradiol alleviated chemotherapy-induced premature ovarian failure by blocking the ferroptosis via activating ESR2/Sirt1/Nrf2 pathway. [Abstract]2025 Oct 29;243(Pt 1):117481. PMID: 41173058 -
Biochem Pharmacol
Sex differences in the metabolic activation of and platelet response to vicagrel in mice: Androgen as a key player. [Abstract]2024 Dec;230(Pt 1):116564. PMID: 39366431 -
Genome Res
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. [Abstract]2024 May 15;34(4):539-555. PMID: 38719469 -
Pain
Difference of pain vulnerability in adult and juvenile rodents: the role of SIRT1-mediated ClC-3 trafficking in sensory neurons. [Abstract]2021 Jun 1;162(6):1882-1896. PMID: 33433144 -
Chem Biol Interact
Autophagy attenuates the secondary senescence of endometrial stromal cells induced by Bisphenol S. [Abstract]2026 Jul 25:435:112138. PMID: 42114668 -
J Ethnopharmacol
Podophyllum hexandrum Royle mitigates perimenopausal symptoms in an OVX rat model by activating the PI3K/AKT/mTOR pathway and enhancing estrogen receptor expression. [Abstract]2025 May 10:119968. PMID: 40354838 -
J Ethnopharmacol
Guizhi Fuling Capsule ameliorates endometrial hyperplasia through promoting p62-Keap1-NRF2-mediated ferroptosis. [Abstract]2021 Jun 28:274:114064. PMID: 33771639 -
Mol Ther Oncolytics
Berberine inhibits carcinogenesis through antagonizing the ATX-LPA-LPAR2-p38-leptin axis in a mouse hepatoma model. [Abstract]2022 Aug 5:26:372-386. PMID: 36090480 -
Cells
Identification of Resistance Genes in Breast Cancer Cells Treated with Fulvestrant and Ribociclib via Retroviral Screening and Integration Site Sequencing. [Abstract]2026 Jan 29;15(3):260. PMID: 41677624 -
J Clin Endocrinol Metab
2021 Apr 23;106(5):1410-1426. PMID: 33524147 -
Inflammation
Large Peritoneal Macrophages Promote the Resolution of Inflammation in Injured Endometrium. [Abstract]2025 Aug 2. PMID: 40751779 -
Int J Mol Sci
2026 May 14;27(10):4354. PMID: 42196334 -
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Int J Mol Sci
Stearoyl-CoA Desaturases1 Accelerates Non-Small Cell Lung Cancer Metastasis by Promoting Aromatase Expression to Improve Estrogen Synthesis. [Abstract]2023 Apr 6;24(7):6826. PMID: 37047797 -
Bioorg Chem
Discovery of the first-in-class highly potent FXR/HSD17B13 dual modulator for the treatment of metabolic dysfunction-associated steatohepatitis. [Abstract]2026 Jul 15:176:109843. PMID: 41962186 -
Int Immunopharmacol
2025 Aug 19:164:115392. PMID: 40834530 -
Int Immunopharmacol
Estrogen deficiency promotes neurodegeneration in female hemi-parkinsonian mice: The role of regulatory T cells. [Abstract]2025 Jan 24:148:114104. PMID: 39862633 -
Int Immunopharmacol
CHS-Ⅳa activates the IGF1R/PI3K signal pathway with inhibited pyroptosis of endometrial stromal cells and progress of endometriosis. [Abstract]2024 Nov 2;143(Pt 3):113527. PMID: 39488924 -
Int Immunopharmacol
Pirfenidone inhibits CCL2-mediated Treg chemotaxis induced by palbociclib and fulvestrant in HR+/HER2- breast cancer. [Abstract]2024 Sep 5;142(Pt A):113059. PMID: 39241517 -
Eur J Pharmacol
Onc201 reduces osteoclastogenesis and prevents ovariectomy-induced bone loss via inhibiting RANKL-induced NFATc1 activation and the integrin signaling pathway. [Abstract]2022 May 15;923:174908. PMID: 35405113 -
Int Immunopharmacol
Estrogen facilitates gastric cancer cell proliferation and invasion through promoting the secretion of interleukin-6 by cancer-associated fibroblasts. [Abstract]2020 Jan;78:105937. PMID: 31753587 -
Neuropharmacology
Dyadic social interaction paradigm reveals selective role of ovarian estrogen in the caring behavior and socially transferred pain in female mice. [Abstract]2024 Sep 5:110138. PMID: 39244013 -
Molecules
Identification of Estradiol Benzoate as an Inhibitor of HBx Using Inducible Stably Transfected HepG2 Cells Expressing HiBiT Tagged HBx. [Abstract]2022 Aug 6;27(15):5000. PMID: 35956950 -
Cell Rep Methods
RECOVER identifies synergistic drug combinations in vitro through sequential model optimization. [Abstract]2023 Oct 23;3(10):100599. PMID: 37797618 -
Cancers (Basel)
2024 Feb 9;16(4):726. PMID: 38398117 -
Aquat Toxicol
2026 Jun 2:298:107880. PMID: 42251851 -
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Poult Sci
Research note: Unveiling the impact of ovotransferrin on chicken primordial germ cells biological processes. [Abstract]2025 May 3;104(7):105259. PMID: 40359719 -
Biochim Biophys Acta Mol Basis Dis
USP46 enhances tamoxifen resistance in breast cancer cells by stabilizing PTBP1 to facilitate glycolysis. [Abstract]2024 Mar;1870(3):167011. PMID: 38176460 -
J Cell Mol Med
Tamoxifen inhibits cell proliferation by impaired glucose metabolism in gallbladder cancer. [Abstract]2020 Jan;24(2):1599-1613. PMID: 31782270 -
Sci Rep
A degrader of HER2 and EGFR abolishes p95HER2 and shows robust antitumor efficacy in HER2-positive breast cancer. [Abstract]2026 Apr 20;16(1):12890. PMID: 42009845 -
Sci Rep
Estrogen regulates duodenal calcium absorption and improves postmenopausal osteoporosis by the effect of ERβ on PMCA1b. [Abstract]2025 May 8;15(1):16053. PMID: 40341576 -
Sci Rep
Comparative analysis of organoid, air-liquid interface, and direct infection models for studying pathogen-host interactions in endometrial tissue. [Abstract]2025 Mar 12;15(1):8531. PMID: 40075187 -
Cell Signal
Estradiol alleviates disease phenotypes caused by m.3635G > a mutations by activating mitochondrial biogenesis and PINK1-Parkin mediated mitophagy in iPSC-derived retinal pigment epithelium cells. [Abstract]2025 Sep 8:136:112121. PMID: 40930474 -
Cell Signal
Inhibitory effects of Eplerenone on angiogenesis via modulating SGK1/TGF-β pathway in contralateral kidney of CKD pregnancy rats. [Abstract]2024 Aug 13:111346. PMID: 39147296 -
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Neurobiol Stress
A sex-dependent delayed maturation of visual plasticity induced by adverse experiences in early childhood. [Abstract]2020 Oct 14;13:100256. PMID: 33344711 -
Mol Hum Reprod
2025 Jul 3;31(3):gaaf037. PMID: 40714816 -
Mol Med Rep
Estrogen inhibits TGF‑β1‑stimulated cardiac fibroblast differentiation and collagen synthesis by promoting Cdc42. [Abstract]2024 Jul;30(1):123. PMID: 38785153 -
Food Chem Toxicol
Gestational cadmium exposure disrupts fetal liver development via repressing estrogen biosynthesis in placental trophoblasts. [Abstract]2023 Jun:176:113807. PMID: 37121429 -
BMC Cancer
PPP4C: a potential molecular marker and therapeutic target in thyroid cancer and triple-negative breast cancer. [Abstract]2026 May 4;26(1):768. PMID: 42082953 -
Life Metab
Intestinal monocarboxylate transporter 1 mediates lactate transport in the gut and regulates metabolic homeostasis of mouse in a sex-dimorphic pattern. [Abstract]2023 Nov 6;3(1):load041. PMID: 39871878 -
BMC Cancer
Immune characteristics analysis and construction of a four-gene prognostic signature for lung adenocarcinoma based on estrogen reactivity. [Abstract]2023 Oct 31;23(1):1047. PMID: 37907850 -
Naunyn Schmiedebergs Arch Pharmacol
Andrographolide blocked the progression of endometriosis by promoting ferroptosis via inhibiting anabolism of serine. [Abstract]2025 Dec 18. PMID: 41408483 -
Mol Reprod Dev
Decreased OGT Attenuates Endometrial Decidualization and Embryo Implantation by Affecting HIF-1α Stability. [Abstract]2025 May;92(5):e70025. PMID: 40342239 -
Genomics
2025 Jan 21;117(2):111002. PMID: 39848478 -
Breast Cancer Res Treat
Monopolar spindle 1 contributes to tamoxifen resistance in breast cancer through phosphorylation of estrogen receptor α. [Abstract]2023 Dec;202(3):595-606. PMID: 37695401 -
Biol Reprod
G protein-coupled estrogen receptor promotes acrosome reaction via regulation of Ca2+ signaling in mouse sperm. [Abstract]2022 Oct 11;107(4):1026-1034. PMID: 35774023 -
J Pharmacol Sci
Gallic acid ameliorates endometrial hyperplasia through the inhibition of the PI3K/AKT pathway and the down-regulation of cyclin D1 expression. [Abstract]2024 May;155(1):1-13. PMID: 38553133 -
Mar Biotechnol (NY)
Reduced Vitellogenin Expression is Associated with Impaired Oogenesis in Female Triploid Pacific Oysters (Crassostrea gigas). [Abstract]2026 Apr 20;28(3):66. PMID: 42008160 -
Genes (Basel)
Effect of Exogenous Hormone on R-Spondin 2 (Rspo2) and R-Spondin 3 (Rspo3) Gene Expression and Embryo Development in Chinese Soft-Shelled Turtle (Pelodiscus sinensis). [Abstract]2023 Jul 19;14(7):1466. PMID: 37510371 -
Front Genet
Genome-wide analysis of the FOXA1 transcriptional regulatory network identifies super enhancer associated LncRNAs in tamoxifen resistance. [Abstract]2022 Sep 20:13:992444. PMID: 36204307 -
J Assist Reprod Genet
High concentration of estrogen resulted by COH may affect the secretion of pro-angiogenic factors in uNK cells by downregulating the expression of IL-11 in decidual stromal cells. [Abstract]2024 Nov;41(11):3189-3200. PMID: 39276273 -
PLoS One
Estrogen protects against liver damage in sepsis through inhibiting oxidative stress mediated activation of pyroptosis signaling pathway. [Abstract]2020 Oct 1;15(10):e0239659. PMID: 33002070 -
J Steroid Biochem Mol Biol
Integrin αVβ3 mediates estrogen to enhance osteoblast proliferation, differentiation, and alleviate OVX-induced postmenopausal osteoporosis. [Abstract]2025 Jun 2:106800. PMID: 40466876 -
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Gene
Sequences analysis and pituitary actions of tachykinins in Chinese sturgeon (Acipenser sinensis). [Abstract]2023 Aug 30:879:147592. PMID: 37356741 -
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Steroids
Exploration of interaction property between nonylphenol and G protein-coupled receptor 30 based on molecular simulation and biological experiments. [Abstract]2022 Dec:188:109114. PMID: 36154832 -
Biochem Biophys Res Commun
Estrogen deficiency impairs double-negative T cell function and activates NF-κB in postmenopausal osteoporosis. [Abstract]2025 Jun 14:776:152212. PMID: 40532308 -
Biochem Biophys Res Commun
Mitochondrial calcium homeostasis mediated by estradiol contributes to atrial fibrillation protection. [Abstract]2025 May 20:772:152050. PMID: 40414005 -
Physiol Rep
Estrogen-dependent gene regulation: Molecular basis of TIMP-1 as a sex-specific biomarker for acute lung injury. [Abstract]2024 Sep;12(17):e70047. PMID: 39267201 -
Zygote
2022 Jun;30(3):330-337. PMID: 34704551 -
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bioRxiv
Breast cancer risk SNPs converge on estrogen receptor binding sites commonly shared between breast tumors to locally alter estrogen signalling output. [Abstract]2023 Nov 2:2023.10.30.564691. PMID: 37961147 -
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Res Sq
Sex differences in viral entry protein expression, host responses to SARS-CoV-2, and in vitro responses to sex steroid hormone treatment in COVID-19. [Abstract]2020 Dec 31:rs.3.rs-100914. PMID: 33173861
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)