Recibokibart
Based on 1 Customer Validation
Recibokibart is a humanized anti-IL-36R IgG1 monoclonal antibody with a KD of 0.104 nM. Recibokibart binds to IL-36R with high affinity, thereby blocking excessive activation of the IL-36 pathway and inhibiting the secretion of the downstream inflammatory cytokine IL-6. Recibokibart can be used for research on generalized pustular psoriasis and hidradenitis suppurativa.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99%
- CAS. Nr.: 2744274-17-5
- Molecular Weight:145.56 kDa
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Speicherung:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
[3]|
IL-36R 0.104 nM (Kd) |
IL-6 0.338 nM (IC50) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Gene ID
Accession
Conjugated
Unconjugated
Reconstitution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-kappa
Anwendung
ELISA, FACS, Functional assay
Verified Bioactivity
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Loaded Recibokibart on AHC2 biosensor, can bind IL-1RL2 Protein, Human (HEK293, His-Avi, HY-P78462) with an affinity constant of 2.879E-09 M as determined in BLI assay.
Chemical Information
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CAS. Nr. 2744274-17-5
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Appearance Liquid
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Molecular Weight 145.56 kDa
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Color Colorless to light yellow
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SMILES
[Recibokibart]
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Versand
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Recibokibart Related Classifications
HY-P991019 Related Classifications
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