RS-56812
RS-56812 is a partial agonist of the 5-HT3 receptor. RS-56812 significantly enhances the propulsive peristalsis of the colon. RS-56812 indirectly enhances cholinergic neurotransmission and improves the working memory performance of non-human primates. RS-56812 is used in research on diarrhea/colon peristalsis and cognitive disorders (such as Alzheimer's disease).
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- CAS. Nr.: 143137-35-3
- Formel: C18H21N3O2
- Molecular Weight:311.38
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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5-HT3 Receptor |
Chemical Information
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CAS. Nr. 143137-35-3
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Molecular Weight 311.38
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Formel C18H21N3O2
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SMILES
O=C(NC1CN2CCC1CC2)C(C3=CN(C)C4=C3C=CC=C4)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Terry AV Jr, et al. The 5-HT3 receptor antagonist, RS-56812, enhances delayed matching performance in monkeys. Neuroreport. 1996 Dec 20;8(1):49-54. [Content Brief]
[2]. Boakye PA, et al. 5-HT(3) and 5-HT(4) receptors contribute to the anti-motility effects of Garcinia buchananii bark extract in the guinea-pig distal colon. Neurogastroenterol Motil. 2012 Jan;24(1):e27-40. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
RS-56812 Related Classifications
HY-135493 Related Classifications
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