STA-2842
STA-2842 is an inhibitor of heat shock protein HSP90 with potential to inhibit autosomal dominant polycystic kidney disease (ADPKD). ADPKD is caused by inherited mutations in the PKD1 or PKD2 genes that abnormally activate multiple signaling proteins and pathways that regulate cell proliferation. STA-2842 can significantly reduce initial renal cyst formation and kidney growth in mice, and slow disease progression in mice with existing cysts.
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- CAS. Nr.: 1046490-67-8
- Formel: C29H38N6O5
- Molecular Weight:550.65
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 1046490-67-8
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Molecular Weight 550.65
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Formel C29H38N6O5
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SMILES
O=C(C1=NN=C(N1C2=CC=C(CN3CCOCC3)C=C2)C4=C(O)C=C(O)C(C(C)C)=C4)NCCN5CCOCC5
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)