VU0431316
VU0431316 is a potent and selective non-competitive antagonist of mGlu5 with an IC50 value of 24 nM.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1620203-63-5
- Formel: C14H9ClN6O2
- Molecular Weight:328.71
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293-A | IC50 |
62.4 nM
Compound: 68, VU0431316
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Negative allosteric modulator activity at rat mGlu5 expressed in HEK293A cells assessed as reduction in glutamate-induced calcium mobilization
Negative allosteric modulator activity at rat mGlu5 expressed in HEK293A cells assessed as reduction in glutamate-induced calcium mobilization
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[PMID: 24969015] |
Chemical Information
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CAS. Nr. 1620203-63-5
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Molecular Weight 328.71
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Formel C14H9ClN6O2
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SMILES
O=C(C1=NC=CC(Cl)=C1)NC2=NC(OC3=CN=CN=C3)=CN=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
VU0431316 Related Classifications
HY-12371 Related Classifications
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