Chitin, from crab carapace (powder),biomedical research grade
Based on 1 Customer Validation
Chitin, from crab carapace (powder),biomedical research grade is a long-chain polymer of N-acetylglucosamine with β-(1-4) linkages. Chitin, from crab carapace (powder),biomedical research grade is found in the exoskeleton of crabs. Chitin, from crab carapace (powder),biomedical research grade inhibits the activation of NF-κB p65, alters the translocation of NF-κB p65 to the nucleus, and interacts with the cell wall of Candida species. Chitin, from crab carapace (powder),biomedical research grade exerts antifungal and anti-inflammatory effects. Chitin, from crab carapace (powder),biomedical research grade can be used in the research of gastric ulcer and candidiasis.
For research use only. We do not sell to patients.
- CAS No.: 1398-61-4
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chitin, from crab carapace (powder),biomedical research grade shows antifungal activity against 20 clinical isolates of Candida spp.[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Wistar rats (10-12 weeks old, 190-210 g) with Ethanol-induced gastric ulcer[2]
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Dosage:150, 300, 600 mg/kg
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Administration:13 days
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Result:Decreased necrotic cells and fat degeneration, and increased normal cells in gastric mucosa.
Chemical Information
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CAS No. 1398-61-4
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Appearance Solid
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Color White to light yellow
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SMILES
[Chitin, from crab carapace (powder),biomedical research grade]
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Initial Source
Holotrichia parallela
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Bernabé P, et al. Chilean crab (Aegla cholchol) as a new source of chitin and chitosan with antifungal properties against Candida spp. Int J Biol Macromol. 2020 Apr 15;149:962-975. [Content Brief]
[2]. Amelia R, et al. Chitin Extracted from the Shell of Blue Swimming Crabs (Portunus pelagicus Linn.) Inhibits NF-kappaB p65 in Ethanol-Induced Gastric Ulcerative Wistar Rats. Mar Drugs. 2023 Sep 12;21(9):488. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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