R18

(Synonyms: PHCVPRDLSWLDLEANMCLP)

R18 is a peptide antagonists of 14-3-3, with a KD of 70-90 nM. R18 efficiently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1.

For research use only. We do not sell to patients.

  • CAS No.: 211364-78-2
  • Formula: C101H157N27O29S3
  • Molecular Weight:2309.69
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All Raf Isoforms

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