Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2438 Results for "
decrease
" in MedChemExpress (MCE) Product Catalog:
Products (2438)
2438 Results for "decrease" in MCE Product Catalog:
Cat. No.: HY-180127
CAS No.: 2728747-80-4
Target:
Research Areas:
UR238 is a proteasome inhibitor. UR238 reduces levels of the immunomodulator HE4. UR238 decreases PDL1 expression on cells. UR238 exhibits anticancer activity against epithelial ovarian cancer .
Cat. No.: HY-N2858
CAS No.: 86989-18-6
Category:
Leguminosae/Fabaceae Extract Plant Coumarins Phenylpropanoids Millettia thonningii (Schumach. & Thonn.) Baker Extract
Target:
Cat. No.: HY-P10305
CAS No.: 2641081-54-9
Synonyms: PB-119
Target:
Research Areas:
Cat. No.: HY-W111168
CAS No.: 3270-25-5
Cat. No.: HY-16164
CAS No.: 57404-51-0
Target:
Research Areas:
DA-11004 is an orally active NADP-dependent isocitrate dehydrogenase (IDPc) inhibitor with an IC50 of 1.49 μM. DA-11004 reduces NADPH production, decreases plasma NADPH levels and plasma free fatty acid levels. DA-11004 lowers plasma glucose levels, inhibits fatty acid synthesis in adipose tissue, reduces weight gain and decreases epididymal and retroperitoneal fat content. DA-11004 exerts antidiabetic effects in mice fed a high-fat and high-sugar diet. DA-11004 can be used for research on obesity and type 2 diabetes .
Cat. No.: HY-B1839R
CAS No.: 79622-59-6
Research Areas:
Fluazinam (Standard) is the analytical standard of Fluazinam (HY-B1839). This product is intended for research and analytical applications. Fluazinam is a broad spectrum pyridinamine fungal inhibitor. Fluazinam is an orally active dinitroaniline fungicide. Fluazinam induces phosphorylation of JNK, activates p38 pathway, decreases Bcl-2, activates caspase-3, decreases complex I activity, increases Autophagy and Apoptosis. Fluazinam has strong antifungal activity against F. fujikuroi and B. maydis. Fluazinam has a negative impact on Brachydanio rerio and worker bees .
Synonyms: meso-Nordihydroguaiaretic acid; meso-NDGA
Category:
Plant Metabolic Disease Phenols Polyphenols Other Families Extract Disease Research Fields
Target:
Synonyms: 20:3 (8Z,11Z,14Z) CE; 20:3 n-6 CE; 20:3 (8Z,11Z,14Z) Cholesterol Ester
Target:
Research Areas:
Cholesteryl homo-γ-linolenate is a cholesterol ester. It accumulates in the adrenal gland of rabbits fed a diet high in linolenic acid.1 Levels of cholesteryl homo-γ-linolenate are decreased and positively correlate with cognitive decline in HIV-infected humans.
Synonyms: NO-1886
Target:
Research Areas:
Ibrolipim (NO-1886) is an orally active lipoprotein lipase (LPL)-promoting agent. Ibrolipim decreases plasma triglycerides, increases high-density lipoprotein cholesterol levels. Ibrolipim has renoprotective and hypolipidemic effects .
Cat. No.: HY-120069
CAS No.: 1415030-15-7
APX2009 is a specific APE1/REF-1 redox inhibitor with anticancer activities which decreases the proliferative, migratory, and invasive properties of breast cancer cell and induces apoptosis in breast cancer cell .
Category:
Plant Lignans Schisandra chinensis (Turcz.) Baill. Extract Phenylpropanoids Schisandraceae Extract Disease Research Fields Inflammation/Immunology
Target:
Research Areas:
Jasmonic acid-d5 is deuterium labeled (±)-Jasmonic acid. (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.
Z-AEVD-FMK is a caspase-10 inhibitor. Z-AEVD-FMK can inhibit the activation of Bid and the release of apoptosis-inducing factor (AIF) in mitochondria in cells, resulting in a significant decrease in the number of apoptotic cells .
TMBIM6 antagonist-1, a potential TMBIM6 antagonist, prevents TMBIM6 binding to mTORC2, decreases mTORC2 activity, and also regulates TMBIM6-leaky Ca 2+ .
Target:
Research Areas:
Etimizol(Ethymisole; Antiffine; Ethylnorantifein) was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain). Etimizol can decrease the K- + permeability of neurons' membrane during action potential.
Cat. No.: HY-15405R
CAS No.: 163451-81-8
Synonyms: A77 1726 (Standard)
Target:
Research Areas:
Teriflunomide (Standard) is the analytical standard of Teriflunomide. This product is intended for research and analytical applications. Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation.
Cat. No.: HY-155415
CAS No.: 2929219-77-0
Target:
Research Areas:
PCSK9-IN-20 (Compound 3i) is a PCSK9 inhibitor with an IC50 of 3.96 µM. PCSK9-IN-20 decreases PCSK9 and increases LDLR protein expression in vitro .
Cat. No.: HY-169334
Target:
Research Areas:
BDK-IN-1 (compound (-)-43) is a BDK inhibitor with the IC50 of 0.23 μM and the max inhibition of 90%. BDK-IN-1 decreases the level of phospho-E1 and can be used for study of cardiometabolic diseases .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
