2. Protein Tyrosine Kinase/RTK
  3. DYRK
  4. Atalaphyllidine

Atalaphyllidine is a natural product. Atalaphyllidine can be isolated from the stem bark of Glycosmis chlorosperma. Atalaphyllidine inhibits DYRK1A kinase activity with an IC50 of 2.2 μM. Atalaphyllidine can be used in the research of neurodegenerative diseases.

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Atalaphyllidine

Atalaphyllidine Chemical Structure

CAS No. : 57959-88-3

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Atalaphyllidine Related Antibodies

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DYRK1 DYRK2 DYRK3 DYRK4 HIPK PRP4

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Description

Atalaphyllidine is a natural product. Atalaphyllidine can be isolated from the stem bark of Glycosmis chlorosperma. Atalaphyllidine inhibits DYRK1A kinase activity with an IC50 of 2.2 μM. Atalaphyllidine can be used in the research of neurodegenerative diseases[1].

IC50 & Target[1]

DYRK1A

2.2 μM (IC50)

In Vitro

Atalaphyllidine (30 min) inhibits DYRK1A kinase activity with an IC50 of 2.2 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Atalaphyllidine Related Antibodies
Molecular Weight

309.32

Formula

C18H15NO4
CAS No.
SMILES

O=C1C2=C(NC3=C4C=CC(C)(C)OC4=CC(O)=C13)C(O)=CC=C2
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Atalaphyllidine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Atalaphyllidine57959-88-3DYRKDual specificity tyrosine phosphorylation regulated kinaseDual specificity tyrosine regulated kinasemouse CLK1down syndromehuman DYRK1AGlu239ATP binding domainratneurodegenerative diseasesLeu241Ile165DYRK1AInhibitorinhibitorinhibit

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