Atalaphyllidine
Atalaphyllidine is a natural product. Atalaphyllidine can be isolated from the stem bark of Glycosmis chlorosperma. Atalaphyllidine inhibits DYRK1A kinase activity with an IC50 of 2.2 μM. Atalaphyllidine can be used in the research of neurodegenerative diseases.
For research use only. We do not sell to patients.
- CAS No.: 57959-88-3
- Formula: C18H15NO4
- Molecular Weight:309.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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DYRK1A 2.2 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
6.98 μM
Compound: 9
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Antiproliferative activity against human A549 cells after 3 days by alamar blue assay
Antiproliferative activity against human A549 cells after 3 days by alamar blue assay
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[PMID: 10217715] |
Atalaphyllidine (30 min) inhibits DYRK1A kinase activity with an IC50 of 2.2 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 57959-88-3
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Molecular Weight 309.32
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Formula C18H15NO4
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SMILES
O=C1C2=C(NC3=C4C=CC(C)(C)OC4=CC(O)=C13)C(O)=CC=C2
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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