Atelopidtoxin
Atelopidtoxin (zetekitoxin) is a toxin (LD50=0.016 mg/kg for mice), which can be isolated from Panamanian frog Atelopus zeteki. Atelopidtoxin causes hypotension and ventricular fibrillation in rabbits. Atelopidtoxin an inhibitor for sodium channel.
For research use only. We do not sell to patients.
- CAS No.: 9061-57-8
- Formula: C16H24N8O12S
- Molecular Weight:552.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 9061-57-8
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Molecular Weight 552.47
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Formula C16H24N8O12S
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SMILES
OC1([C@@]23[C@@]4([H])N(CN(C([C@@]4([H])N=C(N3C[C@]15C[C@](N(C(O5)=O)O)([H])[C@@H](CO)COS(=O)(O)=O)N)=O)O)C(N)=N2)O
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Structure Classification
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Initial Source
Panamanian frog, Atelopus zeteki
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yotsu-Yamashita M, et al. The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki: a potent sodium-channel blocker. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4346-51. [Content Brief]
[2]. Shindelman J, et al., Atelopidtoxin from the Panamanian frog, Atelopus zeteki. Toxicon. 1969 Dec;7(4):315-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)