HPH-15
Based on 1 Customer Validation
HPH-15 is an anti-migration compound that inhibits cell migration by binding to hnRNP U or suppressing TGF-β signaling. In addition, HPH-15 can also inhibit epithelial-mesenchymal transition (EMT). HPH-15 holds promise for research in the fields of anti-tumor metastasis and anti-fibrosis.
For research use only. We do not sell to patients.
- Purity: 99%
- CAS No.: 1009838-93-0
- Formula: C19H31N3S4
- Molecular Weight:429.73
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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All DNA/RNA Synthesis Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | CC50 |
37 μM
Compound: 4, HPH-8
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Cytotoxicity against african green monkey Vero cells after 69 hrs by Alamar blue assay
Cytotoxicity against african green monkey Vero cells after 69 hrs by Alamar blue assay
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[PMID: 17981031] |
| Vero | EC50 |
15 μM
Compound: 4, HPH-8
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Antiviral activity against HSV1 KOS in african green monkey Vero cells by plaque reduction assay
Antiviral activity against HSV1 KOS in african green monkey Vero cells by plaque reduction assay
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[PMID: 17981031] |
Chemical Information
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CAS No. 1009838-93-0
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Appearance Solid
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Molecular Weight 429.73
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Formula C19H31N3S4
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Color Light yellow to yellow
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SMILES
S=C(C1=CC=CC(C(NCCSC(C)(C)C)=S)=N1)NCCSC(C)(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (232.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (264 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3270 mL | 11.6352 mL | 23.2704 mL | 58.1761 mL |
| 5 mM | 0.4654 mL | 2.3270 mL | 4.6541 mL | 11.6352 mL | |
| 10 mM | 0.2327 mL | 1.1635 mL | 2.3270 mL | 5.8176 mL | |
| 15 mM | 0.1551 mL | 0.7757 mL | 1.5514 mL | 3.8784 mL | |
| 20 mM | 0.1164 mL | 0.5818 mL | 1.1635 mL | 2.9088 mL | |
| 25 mM | 0.0931 mL | 0.4654 mL | 0.9308 mL | 2.3270 mL | |
| 30 mM | 0.0776 mL | 0.3878 mL | 0.7757 mL | 1.9392 mL | |
| 40 mM | 0.0582 mL | 0.2909 mL | 0.5818 mL | 1.4544 mL | |
| 50 mM | 0.0465 mL | 0.2327 mL | 0.4654 mL | 1.1635 mL | |
| 60 mM | 0.0388 mL | 0.1939 mL | 0.3878 mL | 0.9696 mL | |
| 80 mM | 0.0291 mL | 0.1454 mL | 0.2909 mL | 0.7272 mL | |
| 100 mM | 0.0233 mL | 0.1164 mL | 0.2327 mL | 0.5818 mL |
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