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Cat. No.: HY-169214

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AV22-149

AV22-149 (compund 22) is an inhibitor of carbonic anhydrase IX.

For research use only. We do not sell to patients.

Formula: C₂₃H₂₈F₃N₃O₆S₂
Molecular Weight:563.61

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

AV22-149 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

AV22-149 (compund 22) is an inhibitor of carbonic anhydrase IX^[1].

IC₅₀ & Target

Carbonic Anhydrase^[1]

All Carbonic Anhydrase Isoforms :

Chemical Information

Molecular Weight 563.61
Formula C₂₃H₂₈F₃N₃O₆S₂
SMILES

NS(=O)(C1=C(F)C(NC2CCCCCCC2)=C(S(CCOC(NC3=CC=CC=C3)=O)(=O)=O)C(F)=C1F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Vaškevičius A, et al. Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX. Elife. 2024 Dec 17;13:RP101401. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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AV22-149

All Carbonic Anhydrase Isoforms